The THAP domain of THAP1 is a large C2CH module with zinc-dependent sequence-specific DNA-binding activity
about
THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor groovesThe THAP-zinc finger protein THAP1 associates with coactivator HCF-1 and O-GlcNAc transferase: a link between DYT6 and DYT3 dystoniasStructure-function analysis of the THAP zinc finger of THAP1, a large C2CH DNA-binding module linked to Rb/E2F pathwaysNMR studies of a new family of DNA binding proteins: the THAP proteinsTHAP5 is a human cardiac-specific inhibitor of cell cycle that is cleaved by the proapoptotic Omi/HtrA2 protease during cell deathMutations in the THAP1 gene are responsible for DYT6 primary torsion dystoniaDNA-binding and -bending activities of SAP30L and SAP30 are mediated by a zinc-dependent module and monophosphoinositidesThe structure and NO binding properties of the nitrophorin-like heme-binding protein from Arabidopsis thaliana gene locus At1g79260.1Structural determinants of specific DNA-recognition by the THAP zinc fingerA divergent P element and its associated MITE, BuT5, generate chromosomal inversions and are widespread within the Drosophila repleta species groupGenetic innovation in vertebrates: gypsy integrase genes and other genes derived from transposable elementsCell growth suppression by thanatos-associated protein 11(THAP11) is mediated by transcriptional downregulation of c-MycDNA transposons and the evolution of eukaryotic genomesGenotype-phenotype correlations in THAP1 dystonia: molecular foundations and description of new cases.The Homeobox Genes of Caenorhabditis elegans and Insights into Their Spatio-Temporal Expression Dynamics during Embryogenesis.The dystonia gene DYT1 is repressed by the transcription factor THAP1 (DYT6).Novel THAP1 sequence variants in primary dystonia.THAP1 mutations (DYT6) are an additional cause of early-onset dystonia.Meiotic silencing and the epigenetics of sexDystonia type 6 gene product Thap1: identification of a 50 kDa DNA-binding species in neuronal nuclear fractionsgon-14 functions with class B and class C synthetic multivulva genes to control larval growth in Caenorhabditis elegans.THAP and ATF-2 regulated sterol carrier protein-2 promoter activities in the larval midgut of the yellow fever mosquito, Aedes aegyptiTHAP5 is a DNA-binding transcriptional repressor that is regulated in melanoma cells during DNA damage-induced cell deathDirect interaction between causative genes of DYT1 and DYT6 primary dystonia.lin-8, which antagonizes Caenorhabditis elegans Ras-mediated vulval induction, encodes a novel nuclear protein that interacts with the LIN-35 Rb proteinSILAC-based quantitative proteomic analysis of human lung cell response to copper oxide nanoparticles.The LIN-15A and LIN-56 transcriptional regulators interact to negatively regulate EGF/Ras signaling in Caenorhabditis elegans vulval cell-fate determination.Genetic and clinical features of primary torsion dystonia.The c.-237_236GA>TT THAP1 sequence variant does not increase risk for primary dystonia.Spo11 and the Formation of DNA Double-Strand Breaks in Meiosis.Identification of the MBF1 heat-response regulon of Arabidopsis thalianaInherited isolated dystonia: clinical genetics and gene function.Alternative approaches to modeling hereditary dystonias.The Foldback-like element Galileo belongs to the P superfamily of DNA transposons and is widespread within the Drosophila genus.DNA-binding sequence specificity of DUX4.Abnormalities of motor function, transcription and cerebellar structure in mouse models of THAP1 dystonia.Identifying the genetic components underlying the pathophysiology of movement disorders.The genetics of dystonias.Identification of multiple binding sites for the THAP domain of the Galileo transposase in the long terminal inverted-repeatsPar-4/THAP1 complex and Notch3 competitively regulated pre-mRNA splicing of CCAR1 and affected inversely the survival of T-cell acute lymphoblastic leukemia cells
P2860
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P2860
The THAP domain of THAP1 is a large C2CH module with zinc-dependent sequence-specific DNA-binding activity
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The THAP domain of THAP1 is a ...... -specific DNA-binding activity
@ast
The THAP domain of THAP1 is a ...... -specific DNA-binding activity
@en
The THAP domain of THAP1 is a ...... -specific DNA-binding activity
@en-gb
The THAP domain of THAP1 is a ...... -specific DNA-binding activity
@nl
type
label
The THAP domain of THAP1 is a ...... -specific DNA-binding activity
@ast
The THAP domain of THAP1 is a ...... -specific DNA-binding activity
@en
The THAP domain of THAP1 is a ...... -specific DNA-binding activity
@en-gb
The THAP domain of THAP1 is a ...... -specific DNA-binding activity
@nl
prefLabel
The THAP domain of THAP1 is a ...... -specific DNA-binding activity
@ast
The THAP domain of THAP1 is a ...... -specific DNA-binding activity
@en
The THAP domain of THAP1 is a ...... -specific DNA-binding activity
@en-gb
The THAP domain of THAP1 is a ...... -specific DNA-binding activity
@nl
P2093
P2860
P356
P1476
The THAP domain of THAP1 is a ...... -specific DNA-binding activity
@en
P2093
Catherine Mathe
François Amalric
Jean-Philippe Girard
Myriam Roussigne
Vincent Ecochard
P2860
P304
P356
10.1073/PNAS.0406882102
P407
P577
2005-04-29T00:00:00Z