THAP1 is a nuclear proapoptotic factor that links prostate-apoptosis-response-4 (Par-4) to PML nuclear bodies - Wikidata - awgldk - TriplyDB

THAP1 is a nuclear proapoptotic factor that links prostate-apoptosis-response-4 (Par-4) to PML nuclear bodies

THAP1 is a nuclear proapoptotic factor that links prostate-apoptosis-response-4 (Par-4) to PML nuclear bodies

http://www.wikidata.org/entity/Q28201432

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THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4 The THAP domain of THAP1 is a large C2CH module with zinc-dependent sequence-specific DNA-binding activity The THAP-zinc finger protein THAP1 associates with coactivator HCF-1 and O-GlcNAc transferase: a link between DYT6 and DYT3 dystonias Structure-function analysis of the THAP zinc finger of THAP1, a large C2CH DNA-binding module linked to Rb/E2F pathways NMR studies of a new family of DNA binding proteins: the THAP proteins Par-4 inhibits Akt and suppresses Ras-induced lung tumorigenesis THAP5 is a human cardiac-specific inhibitor of cell cycle that is cleaved by the proapoptotic Omi/HtrA2 protease during cell death Mutations in the THAP1 gene are responsible for DYT6 primary torsion dystonia Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells THAP11, a novel binding protein of PCBP1, negatively regulates CD44 alternative splicing and cell invasion in a human hepatoma cell line Structure of the C-terminal heme-binding domain of THAP domain containing protein 4 from Homo sapiens Genetic innovation in vertebrates: gypsy integrase genes and other genes derived from transposable elements Cell growth suppression by thanatos-associated protein 11(THAP11) is mediated by transcriptional downregulation of c-Myc Substantia nigra hyperechogenicity in DYT6 dystonia: a pilot study Genotype-phenotype correlations in THAP1 dystonia: molecular foundations and description of new cases.The dystonia gene DYT1 is repressed by the transcription factor THAP1 (DYT6).Human PRKC apoptosis WT1 regulator is a novel PITX2-interacting protein that regulates PITX2 transcriptional activity in ocular cells.Novel THAP1 sequence variants in primary dystonia.Dystonia type 6 gene product Thap1: identification of a 50 kDa DNA-binding species in neuronal nuclear fractions Identification of relevant cancer related-genes in the flat oyster Ostrea edulis affected by disseminated neoplasia.Human THAP7 is a chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressor.THAP5 is a DNA-binding transcriptional repressor that is regulated in melanoma cells during DNA damage-induced cell death Direct interaction between causative genes of DYT1 and DYT6 primary dystonia.Genetic and clinical features of primary torsion dystonia.Inherited isolated dystonia: clinical genetics and gene function.Alternative approaches to modeling hereditary dystonias.Neural expression of the transcription factor THAP1 during development in rat.Lifespan profiles of Alzheimer's disease-associated genes and products in monkeys and mice Phlpp1 facilitates post-traumatic osteoarthritis and is induced by inflammation and promoter demethylation in human osteoarthritis.Identifying the genetic components underlying the pathophysiology of movement disorders.The genetics of dystonias.Mutations in THAP1 (DYT6) in early-onset dystonia: a genetic screening study.Apoptosis and tumor resistance conferred by Par-4 Par-4/THAP1 complex and Notch3 competitively regulated pre-mRNA splicing of CCAR1 and affected inversely the survival of T-cell acute lymphoblastic leukemia cells DYT6 in Brazil: Genetic Assessment and Clinical Characteristics of Patients.Molecular pathways in dystonia.Milestones in dystonia.DYT6 dystonia: review of the literature and creation of the UMD Locus-Specific Database (LSDB) for mutations in the THAP1 gene.Review: genetics and neuropathology of primary pure dystonia.

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THAP1 is a nuclear proapoptotic factor that links prostate-apoptosis-response-4 (Par-4) to PML nuclear bodies

http://www.wikidata.org/entity/Q28201432

description

2003 nî lūn-bûn

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2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2003 թվականի ապրիլին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

THAP1 is a nuclear proapoptoti ...... (Par-4) to PML nuclear bodies

@ast

THAP1 is a nuclear proapoptoti ...... (Par-4) to PML nuclear bodies

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THAP1 is a nuclear proapoptoti ...... (Par-4) to PML nuclear bodies

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type

label

THAP1 is a nuclear proapoptoti ...... (Par-4) to PML nuclear bodies

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THAP1 is a nuclear proapoptoti ...... (Par-4) to PML nuclear bodies

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THAP1 is a nuclear proapoptoti ...... (Par-4) to PML nuclear bodies

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prefLabel

THAP1 is a nuclear proapoptoti ...... (Par-4) to PML nuclear bodies

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THAP1 is a nuclear proapoptoti ...... (Par-4) to PML nuclear bodies

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THAP1 is a nuclear proapoptoti ...... (Par-4) to PML nuclear bodies

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THAP1 is a nuclear proapoptoti ...... (Par-4) to PML nuclear bodies

@en

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Corinne Cayrol

http://www.w3.org/2001/XMLSchema#string

François Amalric

http://www.w3.org/2001/XMLSchema#string

Jean-Philippe Girard

http://www.w3.org/2001/XMLSchema#string

Myriam Roussigne

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Thomas Clouaire

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Molecular cloning and functional analysis of SUT-1, a sulfate transporter from human high endothelial venules

Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1

PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1

Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation

The nuclear dot protein sp100, characterization of domains necessary for dimerization, subcellular localization, and modification by small ubiquitin-like modifiers

pEF-BOS, a powerful mammalian expression vector

Par-4: an emerging pivotal player in neuronal apoptosis and neurodegenerative disorders.

Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body.

Inactivation of the inhibitory kappaB protein kinase/nuclear factor kappaB pathway by Par-4 expression potentiates tumor necrosis factor alpha-induced apoptosis.

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2432-42

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10.1038/SJ.ONC.1206271

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16

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22

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2003-04-24T00:00:00Z

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10785995

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1034863453

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12717420

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apoptotic process