Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7 - Wikidata - awgldk - TriplyDB

Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7

Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7

http://www.wikidata.org/entity/Q24303429

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Identification of residues that confer sugar selectivity to UDP-glycosyltransferase 3A (UGT3A) enzymes Characterization and engineering of the bifunctional N- and O-glucosyltransferase involved in xenobiotic metabolism in plants Structure and Protein-Protein Interactions of Human UDP-Glucuronosyltransferases Glycosyltransferase structural biology and its role in the design of catalysts for glycosylation Anti-cancer drugs elicit re-expression of UDP-glucuronosyltransferases in melanoma cells Transcriptomic and proteomic responses of sweetpotato whitefly, Bemisia tabaci, to thiamethoxam Genetic variations and haplotype diversity of the UGT1 gene cluster in the Chinese population Glucuronidation of dihydrotestosterone and trans-androsterone by recombinant UDP-glucuronosyltransferase (UGT) 1A4: evidence for multiple UGT1A4 aglycone binding sites A High Throughput Assay for Discovery of Bacterial β-Glucuronidase Inhibitors.Potential repurposing of known drugs as potent bacterial β-glucuronidase inhibitors.Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis.Glucuronidation of the steroid enantiomers ent-17β-estradiol, ent-androsterone and ent-etiocholanolone by the human UDP-glucuronosyltransferases.Differences in the glucuronidation of resveratrol and pterostilbene: altered enzyme specificity and potential gender differences Accurate prediction of glucuronidation of structurally diverse phenolics by human UGT1A9 using combined experimental and in silico approaches.First-pass metabolism via UDP-glucuronosyltransferase: a barrier to oral bioavailability of phenolics.Regioselective sulfation and glucuronidation of phenolics: insights into the structural basis.Identification and functional characterization of a novel UDP-glucuronosyltransferase 2A1 splice variant: potential importance in tobacco-related cancer susceptibility.The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis.Mapping the UDP-glucuronic acid binding site in UDP-glucuronosyltransferase-1A10 by homology-based modeling: confirmation with biochemical evidence.Substrate-induced conformational changes in the essential peripheral membrane-associated mannosyltransferase PimA from mycobacteria: implications for catalysis Inter-isoform Hetero-dimerization of Human UDP-Glucuronosyltransferases (UGTs) 1A1, 1A9, and 2B7 and Impacts on Glucuronidation Activity.Structure-function relationships of membrane-associated GT-B glycosyltransferases.Chapter 2: Biogenesis of the cell wall and other glycoconjugates of Mycobacterium tuberculosis.Insights on membrane topology and structure/function of UDP-glucuronosyltransferases.UGT3A: novel UDP-glycosyltransferases of the UGT superfamily.The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families.Substrate inhibition kinetics in drug metabolism reactions.Understanding substrate selectivity of human UDP-glucuronosyltransferases through QSAR modeling and analysis of homologous enzymes.Substrate selectivity of human intestinal UDP-glucuronosyltransferases (UGTs): in silico and in vitro insights.Systematic screening for polymorphisms within the UGT1A6 gene in three Chinese populations and function prediction through structural modeling.Posttranscriptional regulation of uridine diphosphate glucuronosyltransferases.Phenylalanine 93 of the human UGT1A10 plays a major role in the interactions of the enzyme with estrogens.Introduction of an N-Glycosylation Site into UDP-Glucuronosyltransferase 2B3 Alters Its Sensitivity to Cytochrome P450 3A1-Dependent Modulation Effect of UDP-glucuronosyltransferase 2B15 polymorphism on bisphenol A glucuronidation.Identification of UDP glycosyltransferase 3A1 as a UDP N-acetylglucosaminyltransferase.Two Novel Fungal Phenolic UDP Glycosyltransferases from Absidia coerulea and Rhizopus japonicus.Advances in the Understanding of Protein-Protein Interactions in Drug Metabolizing Enzymes through the Use of Biophysical Techniques.Revisiting the Latency of Uridine Diphosphate-Glucuronosyltransferases (UGTs)-How Does the Endoplasmic Reticulum Membrane Influence Their Function?Antennal uridine diphosphate (UDP)-glycosyltransferases in a pest insect: diversity and putative function in odorant and xenobiotics clearance.Single nucleotide polymorphism discovery and functional assessment of variation in the UDP-glucuronosyltransferase 2B7 gene.

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P2860

Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7

http://www.wikidata.org/entity/Q24303429

description

2007 nî lūn-bûn

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2007 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2007 թվականի հունիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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Crystal structure of the cofac ...... DP-glucuronosyltransferase 2B7

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Crystal structure of the cofac ...... DP-glucuronosyltransferase 2B7

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Crystal structure of the cofac ...... DP-glucuronosyltransferase 2B7

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Crystal structure of the cofac ...... DP-glucuronosyltransferase 2B7

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Crystal structure of the cofac ...... DP-glucuronosyltransferase 2B7

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Crystal structure of the cofac ...... DP-glucuronosyltransferase 2B7

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Crystal structure of the cofac ...... DP-glucuronosyltransferase 2B7

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Crystal structure of the cofac ...... DP-glucuronosyltransferase 2B7

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Crystal Structure of the Cofac ...... DP-Glucuronosyltransferase 2B7

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Crystal structure of the cofac ...... DP-glucuronosyltransferase 2B7

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Crystal structure of the cofac ...... DP-glucuronosyltransferase 2B7

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Crystal structure of the cofac ...... DP-glucuronosyltransferase 2B7

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Crystal structure of the cofac ...... DP-glucuronosyltransferase 2B7

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J.JMB.2007.03.066

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Journal of Molecular Biology

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Crystal structure of the cofac ...... DP-glucuronosyltransferase 2B7

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Agnieszka K Zielinska

http://www.w3.org/2001/XMLSchema#string

Anna Radominska-Pandya

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Jeffrey E Keenan

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Michael J Miley

http://www.w3.org/2001/XMLSchema#string

Stacie M Bratton

http://www.w3.org/2001/XMLSchema#string

P2860

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Structure of the UDP-glucosyltransferase GtfB that modifies the heptapeptide aglycone in the biosynthesis of vancomycin group antibiotics

High resolution crystal structures of T4 phage beta-glucosyltransferase: induced fit and effect of substrate and metal binding

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498-511

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scholarly article

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2572247

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10.1016/J.JMB.2007.03.066

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P407

P433

2

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369

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Matthew R Redinbo

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2007-06-01T00:00:00Z

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6386996

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17442341

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cellular glucuronidation

UDP glucuronosyltransferase family 2 member B7

crystal structure

P932

1976284

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