The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families.
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Identification of residues that confer sugar selectivity to UDP-glycosyltransferase 3A (UGT3A) enzymesIn the hunt for genomic markers of metabolic resistance to pyrethroids in the mosquito Aedes aegypti: An integrated next-generation sequencing approachAccurate prediction of glucuronidation of structurally diverse phenolics by human UGT1A9 using combined experimental and in silico approaches.First-pass metabolism via UDP-glucuronosyltransferase: a barrier to oral bioavailability of phenolics.Regioselective sulfation and glucuronidation of phenolics: insights into the structural basis.Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions.Substrate inhibition kinetics in drug metabolism reactions.Understanding substrate selectivity of human UDP-glucuronosyltransferases through QSAR modeling and analysis of homologous enzymes.Substrate selectivity of human intestinal UDP-glucuronosyltransferases (UGTs): in silico and in vitro insights.Glucuronides from metabolites to medicines: a survey of the in vivo generation, chemical synthesis and properties of glucuronides.Posttranscriptional regulation of uridine diphosphate glucuronosyltransferases.Two Novel Fungal Phenolic UDP Glycosyltransferases from Absidia coerulea and Rhizopus japonicus.Characterization of a membrane-bound C-glucosyltransferase responsible for carminic acid biosynthesis in Dactylopius coccus Costa.Posttranscriptional regulation of UGT2B10 hepatic expression and activity by alternative splicing.3D-QSAR studies on UDP-glucuronosyltransferase 2B7 substrates using the pharmacophore and VolSurf approaches.Chiral Inhibition of Rivaroxaban Derivatives Towards UDP-Glucuronosyltransferase (UGT) Isoforms.Glucuronidation: driving factors and their impact on glucuronide disposition
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P2860
The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 2010
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
The crystal structure of human ...... m both the 1A and 2B families.
@en
The crystal structure of human ...... m both the 1A and 2B families.
@nl
type
label
The crystal structure of human ...... m both the 1A and 2B families.
@en
The crystal structure of human ...... m both the 1A and 2B families.
@nl
prefLabel
The crystal structure of human ...... m both the 1A and 2B families.
@en
The crystal structure of human ...... m both the 1A and 2B families.
@nl
P2093
P2860
P1476
The crystal structure of human ...... m both the 1A and 2B families.
@en
P2093
Anna Radominska-Pandya
Michael J Miley
Stacie M Bratton
P2860
P304
P356
10.3109/03602530903209049
P407
P577
2010-02-01T00:00:00Z