about
SH3 binding domains in the dopamine D4 receptorFunctional Selectivity and Classical Concepts of Quantitative PharmacologySNX27 mediates PDZ-directed sorting from endosomes to the plasma membraneSNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors.The ubiquitin-like protein PLIC-2 is a negative regulator of G protein-coupled receptor endocytosis.DISC1 regulates primary cilia that display specific dopamine receptorsUbiquitination regulates proteolytic processing of G protein-coupled receptors after their sorting to lysosomesNeurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neuronsRole of PDZ proteins in regulating trafficking, signaling, and function of GPCRs: means, motif, and opportunityStructure of an Arrestin2-Clathrin Complex Reveals a Novel Clathrin Binding Domain That Modulates Receptor TraffickingEndocytosis promotes rapid dopaminergic signalingDysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomesA simple cell-based assay reveals that diverse neuropsychiatric risk genes converge on primary ciliaMorphine promotes rapid, arrestin-dependent endocytosis of mu-opioid receptors in striatal neurons{Beta}-blocker drugs mediate calcium signaling in native central nervous system neurons by {beta}-arrestin-biased agonismEngineered protein connectivity to actin mimics PDZ-dependent recycling of G protein-coupled receptors but not its regulation by HrsMicrotubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctionsCargo-mediated regulation of a rapid Rab4-dependent recycling pathwaySequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains.The role of ubiquitination in lysosomal trafficking of δ-opioid receptors.Conformational biosensors reveal GPCR signalling from endosomes.Identification of protein interactions by yeast two-hybrid screening and coimmunoprecipitation.Mass spectrometric analysis of agonist effects on posttranslational modifications of the beta-2 adrenoceptor in mammalian cells.Investigating signaling consequences of GPCR trafficking in the endocytic pathway.Functional characterization of vasopressin type 2 receptor substitutions (R137H/C/L) leading to nephrogenic diabetes insipidus and nephrogenic syndrome of inappropriate antidiuresis: implications for treatments.Essential role of Hrs in a recycling mechanism mediating functional resensitization of cell signaling.Association of mu-opioid receptor variants and response to citalopram treatment in major depressive disorderEndocytosis, signaling, and beyondRegulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization.Rapid delivery of internalized signaling receptors to the somatodendritic surface by sequence-specific local insertion.A chemical screen identifies class a g-protein coupled receptors as regulators of cilia.Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosisGPR88 reveals a discrete function of primary cilia as selective insulators of GPCR cross-talkDifferential activation and trafficking of micro-opioid receptors in brain slices.G protein-coupled receptor (GPCR) signaling via heterotrimeric G proteins from endosomes.Regulated endocytosis of opioid receptors: cellular mechanisms and proposed roles in physiological adaptation to opiate drugs.The golgi-associated PDZ domain protein PIST/GOPC stabilizes the β1-adrenergic receptor in intracellular compartments after internalization.Ubiquitination in the first cytoplasmic loop of μ-opioid receptors reveals a hierarchical mechanism of lysosomal down-regulation.Mechanisms regulating membrane trafficking of G protein-coupled receptors in the endocytic pathway.Real-time imaging of discrete exocytic events mediating surface delivery of AMPA receptors.
P50
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P50
name
Mark von Zastrow
@en
type
label
Mark von Zastrow
@en
prefLabel
Mark von Zastrow
@en