about
MAPK scaffold IQGAP1 binds the EGF receptor and modulates its activationIQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistanceRaf family kinases: old dogs have learned new tricksIQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration.IQGAP1 integrates Ca2+/calmodulin and B-Raf signalingGet to grips: steering local actin dynamics with IQGAPsIQGAPs in cancer: a family of scaffold proteins underlying tumorigenesisThe biology of IQGAP proteins: beyond the cytoskeletonThe Salmonella SPI2 effector SseI mediates long-term systemic infection by modulating host cell migrationCdc42 and k-Ras Control Endothelial Tubulogenesis through Apical Membrane and Cytoskeletal Polarization: Novel Stimulatory Roles for GTPase Effectors, the Small GTPases, Rac2 and Rap1b, and Inhibitory Influence of Arhgap31 and Rasa1IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cellsHierarchical scaffolding of an ERK1/2 activation pathwayIQGAP3 is essential for cell proliferation and motility during zebrafish embryonic development.IQGAP1-dependent signaling pathway regulates endothelial cell proliferation and angiogenesis.Induction of erythroid differentiation in human erythroleukemia cells by depletion of malic enzyme 2Citrate Suppresses Tumor Growth in Multiple Models through Inhibition of Glycolysis, the Tricarboxylic Acid Cycle and the IGF-1R Pathway.IQGAP1 plays an important role in the invasiveness of thyroid cancerSalmonella enterica serotype Typhimurium usurps the scaffold protein IQGAP1 to manipulate Rac1 and MAPK signalling.S100P is a novel interaction partner and regulator of IQGAP1IQGAP1 in microbial pathogenesis: Targeting the actin cytoskeleton.IQGAP1 regulates NR2A signaling, spine density, and cognitive processes.IQGAPs choreograph cellular signaling from the membrane to the nucleusHost and bacterial proteins that repress recruitment of LC3 to Shigella early during infection.IQGAP1 and its binding proteins control diverse biological functions.The Overexpression of IQGAP1 and β-Catenin Is Associated with Tumor Progression in Hepatocellular Carcinoma In Vitro and In Vivo.IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload.Shigella Effector OspB Activates mTORC1 in a Manner That Depends on IQGAP1 and Promotes Cell Proliferation.Biochemical analysis of the interactions of IQGAP1 C-terminal domain with CDC42Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments.ERK1/2 activation in heart is controlled by melusin, focal adhesion kinase and the scaffold protein IQGAP1Protein scaffolds in MAP kinase signalling.The Ras GTPase-activating-like protein IQGAP1 mediates Nrf2 protein activation via the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)-ERK pathway.Structure and function of IQ-domain GTPase-activating protein 1 and its association with tumor progression (Review).Conserved sequence repeats of IQGAP1 mediate binding to EzrinIQGAP1 binds to estrogen receptor-α and modulates its function.Mechanistic principles of RAF kinase signaling.The ERK Cascade: Distinct Functions within Various Subcellular Organelles.IQGAP1: a regulator of intracellular spacetime relativity.Mitogen-Activated Protein (MAP) Kinase Scaffolding Proteins: A Recount.Key role of ERK1/2 molecular scaffolds in heart pathology.
P2860
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P248
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P2860
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
IQGAP1 modulates activation of B-Raf
@ast
IQGAP1 modulates activation of B-Raf
@en
IQGAP1 modulates activation of B-Raf
@en-gb
IQGAP1 modulates activation of B-Raf
@nl
type
label
IQGAP1 modulates activation of B-Raf
@ast
IQGAP1 modulates activation of B-Raf
@en
IQGAP1 modulates activation of B-Raf
@en-gb
IQGAP1 modulates activation of B-Raf
@nl
prefLabel
IQGAP1 modulates activation of B-Raf
@ast
IQGAP1 modulates activation of B-Raf
@en
IQGAP1 modulates activation of B-Raf
@en-gb
IQGAP1 modulates activation of B-Raf
@nl
P2093
P2860
P921
P356
P1476
IQGAP1 modulates activation of B-Raf
@en
P2093
David B Sacks
Jian-Guo Ren
Zhigang Li
P2860
P304
P356
10.1073/PNAS.0611308104
P407
P577
2007-06-19T00:00:00Z