MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1
about
CELF family RNA-binding protein UNC-75 regulates two sets of mutually exclusive exons of the unc-32 gene in neuron-specific manners in Caenorhabditis elegansAlternative splicing of myomesin 1 gene is aberrantly regulated in myotonic dystrophy type 1MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3Evaluating the effects of CELF1 deficiency in a mouse model of RNA toxicityDevelopment of an AP-FRET based analysis for characterizing RNA-protein interactions in myotonic dystrophy (DM1)Ultrasound-enhanced delivery of morpholino with Bubble liposomes ameliorates the myotonia of myotonic dystrophy model miceExpanded CCUG repeat RNA expression in Drosophila heart and muscle trigger Myotonic Dystrophy type 1-like phenotypes and activate autophagocytosis genes.Autoregulation of MBNL1 function by exon 1 exclusion from MBNL1 transcript.Two high-throughput screening assays for aberrant RNA-protein interactions in myotonic dystrophy type 1.MBNL proteins and their target RNAs, interaction and splicing regulation.Alternative splicing of the neurofibromatosis type 1 pre-mRNA is regulated by the muscleblind-like proteins and the CUG-BP and ELAV-like factorsTrinucleotide expansion in disease: why is there a length threshold?Dissecting domains necessary for activation and repression of splicing by Muscleblind-like protein 1Overexpression of CUGBP1 in skeletal muscle from adult classic myotonic dystrophy type 1 but not from myotonic dystrophy type 2.Autoregulated splicing of muscleblind-like 1 (MBNL1) Pre-mRNA.Dose-Dependent Regulation of Alternative Splicing by MBNL Proteins Reveals Biomarkers for Myotonic DystrophyIn Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide MetforminManumycin A corrects aberrant splicing of Clcn1 in myotonic dystrophy type 1 (DM1) mice.Bidirectional transcription of trinucleotide repeats: roles for excision repair.FUS/TLS acts as an aggregation-dependent modifier of polyglutamine disease model mice.Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2MBNL1-RNA recognition: contributions of MBNL1 sequence and RNA conformation.Repeat expansion diseases: when a good RNA turns bad.Structural disorder and the loss of RNA homeostasis in aging and neurodegenerative disease.Brain pathology in myotonic dystrophy: when tauopathy meets spliceopathy and RNAopathy.ABLIM1 splicing is abnormal in skeletal muscle of patients with DM1 and regulated by MBNL, CELF and PTBP1.Can Human Pluripotent Stem Cell-Derived Cardiomyocytes Advance Understanding of Muscular Dystrophies?Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy.Intracellular localization and splicing regulation of FUS/TLS are variably affected by amyotrophic lateral sclerosis-linked mutations.Position-dependent and neuron-specific splicing regulation by the CELF family RNA-binding protein UNC-75 in Caenorhabditis elegans.Phenylbutazone induces expression of MBNL1 and suppresses formation of MBNL1-CUG RNA foci in a mouse model of myotonic dystrophy.Helicobacter pylori-induced STAT3 activation and signalling network in gastric cancer.Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functionsSplicing of human chloride channel 1.Hybrid splicing minigene and antisense oligonucleotides as efficient tools to determine functional protein/RNA interactions.MBNL expression in autoregulatory feedback loops.Alternative Splicing of Transcription Factors Genes in Muscle Physiology and Pathology.Bruno-3 regulates sarcomere component expression and contributes to muscle phenotypes of myotonic dystrophy type 1.
P2860
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P2860
MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
MBNL and CELF proteins regulat ...... muscle chloride channel CLCN1
@ast
MBNL and CELF proteins regulat ...... muscle chloride channel CLCN1
@en
MBNL and CELF proteins regulat ...... muscle chloride channel CLCN1
@en-gb
MBNL and CELF proteins regulat ...... muscle chloride channel CLCN1
@nl
type
label
MBNL and CELF proteins regulat ...... muscle chloride channel CLCN1
@ast
MBNL and CELF proteins regulat ...... muscle chloride channel CLCN1
@en
MBNL and CELF proteins regulat ...... muscle chloride channel CLCN1
@en-gb
MBNL and CELF proteins regulat ...... muscle chloride channel CLCN1
@nl
prefLabel
MBNL and CELF proteins regulat ...... muscle chloride channel CLCN1
@ast
MBNL and CELF proteins regulat ...... muscle chloride channel CLCN1
@en
MBNL and CELF proteins regulat ...... muscle chloride channel CLCN1
@en-gb
MBNL and CELF proteins regulat ...... muscle chloride channel CLCN1
@nl
P2093
P2860
P921
P3181
P356
P1476
MBNL and CELF proteins regulat ...... muscle chloride channel CLCN1
@en
P2093
Chika Washizu
Hayato Onishi
Noboru Sasagawa
Nobuyuki Nukina
Shoichi Ishiura
Yoshihiro Kino
Yuriko Nezu
P2860
P304
P3181
P356
10.1093/NAR/GKP681
P407
P577
2009-10-01T00:00:00Z