MBNL1-RNA recognition: contributions of MBNL1 sequence and RNA conformation.
about
Crystallographic characterization of CCG repeatsSingle-molecule study of the CUG repeat-MBNL1 interaction and its inhibition by small molecules.Examining the interactions of the splicing factor MBNL1 with target RNA sequences via a label-free, multiplex methodStructure of the myotonic dystrophy type 2 RNA and designed small molecules that reduce toxicity.Computational investigation of RNA CUG repeats responsible for myotonic dystrophy 1Circular RNA participates in the carcinogenesis and the malignant behavior of cancer.MBNL proteins and their target RNAs, interaction and splicing regulation.Modifications to toxic CUG RNAs induce structural stability, rescue mis-splicing in a myotonic dystrophy cell model and reduce toxicity in a myotonic dystrophy zebrafish model.Developing bivalent ligands to target CUG triplet repeats, the causative agent of myotonic dystrophy type 1.Dissecting domains necessary for activation and repression of splicing by Muscleblind-like protein 1RNA-binding protein misregulation in microsatellite expansion disordersRNA Structures as Mediators of Neurological Diseases and as Drug Targets.The Sequence and Structure Determine the Function of Mature Human miRNAs.Structural Characteristics of Simple RNA Repeats Associated with Disease and their Deleterious Protein Interactions.Structures of RNA repeats associated with neurological diseases.Combinatorial mutagenesis of MBNL1 zinc fingers elucidates distinct classes of regulatory eventsA novel CUG(exp)·MBNL1 inhibitor with therapeutic potential for myotonic dystrophy type 1.Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T.An engineered RNA binding protein with improved splicing regulation.Pseudouridine Modification Inhibits Muscleblind-like 1 (MBNL1) Binding to CCUG Repeats and Minimally Structured RNA through Reduced RNA Flexibility.
P2860
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P2860
MBNL1-RNA recognition: contributions of MBNL1 sequence and RNA conformation.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
MBNL1-RNA recognition: contributions of MBNL1 sequence and RNA conformation.
@en
MBNL1-RNA recognition: contributions of MBNL1 sequence and RNA conformation.
@nl
type
label
MBNL1-RNA recognition: contributions of MBNL1 sequence and RNA conformation.
@en
MBNL1-RNA recognition: contributions of MBNL1 sequence and RNA conformation.
@nl
prefLabel
MBNL1-RNA recognition: contributions of MBNL1 sequence and RNA conformation.
@en
MBNL1-RNA recognition: contributions of MBNL1 sequence and RNA conformation.
@nl
P2093
P2860
P356
P1433
P1476
MBNL1-RNA recognition: contributions of MBNL1 sequence and RNA conformation.
@en
P2093
Anne M Baranger
Nejmun Hussain
Sreenivasa Rao Ramisetty
P2860
P304
P356
10.1002/CBIC.201100487
P577
2011-11-22T00:00:00Z