Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy
about
Guidelines for the use and interpretation of assays for monitoring autophagyGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresomeThe mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagyGenome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagyMitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagyp62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for bothAMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1CLUH regulates mitochondrial biogenesis by binding mRNAs of nuclear-encoded mitochondrial proteinsClass IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactinHsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagyBroad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagyChaperone-Mediated Autophagy and Mitochondrial Homeostasis in Parkinson's DiseaseMitochondrial Dysfunction in Alzheimer's Disease and the Rationale for Bioenergetics Based TherapiesParkin Regulation and Neurodegenerative DisordersMitochondria-Targeted Protective Compounds in Parkinson's and Alzheimer's DiseasesMetabolic reprogramming by class I and II histone deacetylasesMitophagy in hematopoietic stem cells: the case for explorationNew insights into the role of mitochondrial dynamics and autophagy during oxidative stress and aging in the heartMitochondria and the autophagy-inflammation-cell death axis in organismal agingMitochondrial dynamics and mitophagy in Parkinson's disease: disordered cellular power plant becomes a big deal in a major movement disorderUbiquitination and phosphorylation of Beclin 1 and its binding partners: Tuning class III phosphatidylinositol 3-kinase activity and tumor suppressionThe pathways of mitophagy for quality control and clearance of mitochondriaMechanisms of mitochondria and autophagy crosstalkHDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration.Mechanisms of mitophagyA molecular explanation for the recessive nature of parkin-linked Parkinson’s diseaseMitochondrial dynamics and viral infections: A close nexusMitochondrial regulation of β-cell function: maintaining the momentum for insulin releaseAutophagosome dynamics in neurodegeneration at a glanceMitochondrial dysfunction associated with glucocerebrosidase deficiencyATP13A2 and Alpha-synuclein: a Metal Taste in AutophagyMolecular chaperone-mediated rescue of mitophagy by a Parkin RING1 domain mutantEvidence for a common biological pathway linking three Parkinson's disease-causing genes: parkin, PINK1 and DJ-1Autophagy in Neurodegenerative Diseases and Metal NeurotoxicitySelective autophagy mediated by autophagic adapter proteinsCholine dehydrogenase interacts with SQSTM1/p62 to recruit LC3 and stimulate mitophagyMitophagy mechanisms and role in human diseasesMacroautophagy and cell responses related to mitochondrial dysfunction, lipid metabolism and unconventional secretion of proteins
P2860
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P248
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P2860
Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Disease-causing mutations in p ...... and HDAC6-dependent mitophagy
@ast
Disease-causing mutations in p ...... and HDAC6-dependent mitophagy
@en
Disease-causing mutations in p ...... and HDAC6-dependent mitophagy
@en-gb
Disease-causing mutations in p ...... and HDAC6-dependent mitophagy
@nl
type
label
Disease-causing mutations in p ...... and HDAC6-dependent mitophagy
@ast
Disease-causing mutations in p ...... and HDAC6-dependent mitophagy
@en
Disease-causing mutations in p ...... and HDAC6-dependent mitophagy
@en-gb
Disease-causing mutations in p ...... and HDAC6-dependent mitophagy
@nl
prefLabel
Disease-causing mutations in p ...... and HDAC6-dependent mitophagy
@ast
Disease-causing mutations in p ...... and HDAC6-dependent mitophagy
@en
Disease-causing mutations in p ...... and HDAC6-dependent mitophagy
@en-gb
Disease-causing mutations in p ...... and HDAC6-dependent mitophagy
@nl
P2093
P2860
P921
P3181
P356
P1476
Disease-causing mutations in p ...... and HDAC6-dependent mitophagy
@en
P2093
J Paul Taylor
Joo-Yong Lee
Kah Leong Lim
Tso-Pang Yao
Yoshito Nagano
P2860
P3181
P356
10.1083/JCB.201001039
P407
P577
2010-05-17T00:00:00Z