Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP - Wikidata - awgldk - TriplyDB

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

http://www.wikidata.org/entity/Q24311629

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GTP cyclohydrolase I feedback regulatory protein is a pentamer of identical subunits. Purification, cDNA cloning, and bacterial expression A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions Tetrahydrobiopterin biosynthesis, regeneration and functions Deficient BH4 production via de novo and salvage pathways regulates NO responses to cytokines in adult cardiac myocytes Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression Recoupling the cardiac nitric oxide synthases: tetrahydrobiopterin synthesis and recycling Nitric oxide synthases in heart failure Dwarfism and low insulin-like growth factor-1 due to dopamine depletion in Pts-/- mice rescued by feeding neurotransmitter precursors and H4-biopterin Ligand binding to the inhibitory and stimulatory GTP cyclohydrolase I/GTP cyclohydrolase I feedback regulatory protein complexes Structural basis of biopterin-induced inhibition of GTP cyclohydrolase I by GFRP, its feedback regulatory protein Decameric GTP cyclohydrolase I forms complexes with two pentameric GTP cyclohydrolase I feedback regulatory proteins in the presence of phenylalanine or of a combination of tetrahydrobiopterin and GTP The protein partners of GTP cyclohydrolase I in rat organs The mechanism of potent GTP cyclohydrolase I inhibition by 2,4-diamino-6-hydroxypyrimidine: requirement of the GTP cyclohydrolase I feedback regulatory protein Tetrahydrobiopterin in cardiovascular health and disease.Catecholamine biosynthesis and physiological regulation in neuroendocrine cells.Bacterial lipopolysaccharide down-regulates expression of GTP cyclohydrolase I feedback regulatory protein.Characterization of cerebral microvasculature in transgenic mice with endothelium targeted over-expression of GTP-cyclohydrolase I.Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase I.Biochemical characterization of the tetrahydrobiopterin synthesis pathway in the oleaginous fungus Mortierella alpina.Correction of murine PKU following AAV-mediated intramuscular expression of a complete phenylalanine hydroxylating system Enhancement of folates in plants through metabolic engineering.Characterization of transgenic Gfrp knock-in mice: implications for tetrahydrobiopterin in modulation of normal tissue radiation responses Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease.Biosynthesis of drosopterins, the red eye pigments of Drosophila melanogaster.GTP cyclohydrolase I inhibition by the prototypic inhibitor 2, 4-diamino-6-hydroxypyrimidine. Mechanisms and unanticipated role of GTP cyclohydrolase I feedback regulatory protein.Interaction of human GTP cyclohydrolase I with its splice variants.GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin levels, independent of GTP cyclohydrolase feedback regulatory protein expression.Direct binding of GTP cyclohydrolase and tyrosine hydroxylase: regulatory interactions between key enzymes in dopamine biosynthesis Identification of abundant mRNAs from the third stage larvae of the parasitic nematode, ostertagia ostertagi.Involvement of sphingosine kinase in TNF-alpha-stimulated tetrahydrobiopterin biosynthesis in C6 glioma cells.Tetrahydrobiopterin, a critical factor in the production and role of nitric oxide in mast cells.A typical N-terminal extensions confer novel regulatory properties on GTP cyclohydrolase isoforms in Drosophila melanogaster.Phosphorylation of GTP cyclohydrolase I and modulation of its activity in rodent mast cells. GTP cyclohydrolase I hyperphosphorylation is coupled to high affinity IgE receptor signaling and involves protein kinase C.GTP cyclohydrolase I feedback regulatory protein is expressed in serotonin neurons and regulates tetrahydrobiopterin biosynthesis.Development of the pteridine pathway in the zebrafish, Danio rerio.The role of tetrahydrobiopterin in inflammation and cardiovascular disease.Divergence in regulation of nitric-oxide synthase and its cofactor tetrahydrobiopterin by tumor necrosis factor-alpha. Ceramide potentiates nitric oxide synthesis without affecting GTP cyclohydrolase I activity.

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P2860

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

http://www.wikidata.org/entity/Q24311629

description

1996 nî lūn-bûn

@nan

1996 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

1996 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

1996年の論文

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1996年論文

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1996年論文

@zh-hant

1996年論文

@zh-hk

1996年論文

@zh-mo

1996年論文

@zh-tw

1996年论文

@wuu

name

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

@ast

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

@en

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

@en-gb

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

@nl

type

label

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

@ast

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

@en

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

@en-gb

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

@nl

prefLabel

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

@ast

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

@en

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

@en-gb

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

@nl

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P356

JBC.271.33.19743

P1433

Journal of Biological Chemistry

P1476

Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP

@en

P2093

D Kowlessur

http://www.w3.org/2001/XMLSchema#string

H Jaffe

http://www.w3.org/2001/XMLSchema#string

S Milstien

http://www.w3.org/2001/XMLSchema#string

T I Bonner

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P2860

The application of 8-aminoguanosine triphosphate, a new inhibitor of GTP cyclohydrolase I, to the purification of the enzyme from human liver

Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene

Human GTP cyclohydrolase I: only one out of three cDNA isoforms gives rise to the active enzyme

Induction of GTP cyclohydrolase I by bacterial lipopolysaccharide in the rat

Feedback regulation mechanisms for the control of GTP cyclohydrolase I activity

Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity.

Tetrahydrobiopterin increases in adrenal medulla and cortex: a factor in the regulation of tyrosine hydroxylase.

GTP cyclohydrolase I deficiency, a new enzyme defect causing hyperphenylalaninemia with neopterin, biopterin, dopamine, and serotonin deficiencies and muscular hypotonia.

Tetrahydrobiopterin cofactor biosynthesis: GTP cyclohydrolase I mRNA expression in rat brain and superior cervical ganglia.

Biopterin derivatives in normal and phenylketonuric patients after oral loads of L-phenylalanine, L-tyrosine, and L-tryptophan.

P304

19743-51

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scholarly article

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10.1074/JBC.271.33.19743

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P433

33

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271

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1996-08-16T00:00:00Z

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P5875

14499026

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P698

8702680

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P921

neurotransmitter metabolic process

GTP cyclohydrolase I feedback regulator