Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL
about
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1Prolyl 4-hydroxylaseThe Role of Oxygen Sensors, Hydroxylases, and HIF in Cardiac Function and DiseaseGenetic deletion of Rnd3/RhoE results in mouse heart calcium leakage through upregulation of protein kinase A signaling.Prolyl hydroxylase 2: a novel regulator of β2 -adrenoceptor internalization.Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase.Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling.PHD3-mediated prolyl hydroxylation of nonmuscle actin impairs polymerization and cell motility.Roles of individual prolyl-4-hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice.Cullins and cancer.Palmitoylation regulates intracellular trafficking of β2 adrenergic receptor/arrestin/phosphodiesterase 4D complexes in cardiomyocytes.Deficiency of a transmembrane prolyl 4-hydroxylase in the zebrafish leads to basement membrane defects and compromised kidney functionLoss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR.Beta2-adrenergic receptor lysosomal trafficking is regulated by ubiquitination of lysyl residues in two distinct receptor domains.The contributions of HIF-target genes to tumor growth in RCC.Prolyl-4-hydroxylase 3 (PHD3) expression is downregulated during epithelial-to-mesenchymal transition.Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling.Regulation of cellular levels of Sprouty2 protein by prolyl hydroxylase domain and von Hippel-Lindau proteinsIdentification of prolyl hydroxylation modifications in mammalian cell proteins.Ascorbic acid regulates osterix expression in osteoblasts by activation of prolyl hydroxylase and ubiquitination-mediated proteosomal degradation pathwayProtein-protein interactions at the adrenergic receptors.PHD3 Stabilizes the Tight Junction Protein Occludin and Protects Intestinal Epithelial Barrier Function.A Perspective on Studying G-Protein-Coupled Receptor Signaling with Resonance Energy Transfer Biosensors in Living Organisms.PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban.Hypoxia-inducible factor prolyl hydroxylase inhibition: robust new target or another big bust for stroke therapeutics?PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response.S-nitrosylation: integrator of cardiovascular performance and oxygen delivery.Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes.EGLN3 inhibition of NF-κB is mediated by prolyl hydroxylase-independent inhibition of IκB kinase γ ubiquitinationHypoxia sensing through β-adrenergic receptors.Neuronal apoptosis by prolyl hydroxylation: implication in nervous system tumours and the Warburg conundrum.The polycystins are modulated by cellular oxygen-sensing pathways and regulate mitochondrial function.Prolyl-hydroxylase 3: Evolving Roles for an Ancient Signaling ProteinPotential regulation of glioma through the induction of apoptosis signaling via Egl-9 family hypoxia-inducible factor 3Cullin-RING Ligases as attractive anti-cancer targets.Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by "antioxidant" metal chelators: From ferroptosis to stroke.Prolyl 4-hydroxylases, master regulators of the hypoxia response.PHD1 regulates p53-mediated colorectal cancer chemoresistance.PHD3 regulates EGFR internalization and signalling in tumours.Prolyl hydroxylase domain enzymes: important regulators of cancer metabolism.
P2860
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P2860
Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL
description
2009 nî lūn-bûn
@nan
2009 թուականին հրատարակուած գիտական յօդուած
@hyw
2009 թվականին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Oxygen-regulated beta(2)-adren ...... LN3 and ubiquitylation by pVHL
@ast
Oxygen-regulated beta(2)-adren ...... LN3 and ubiquitylation by pVHL
@en
Oxygen-regulated beta(2)-adren ...... LN3 and ubiquitylation by pVHL
@en-gb
Oxygen-regulated beta(2)-adren ...... LN3 and ubiquitylation by pVHL
@nl
type
label
Oxygen-regulated beta(2)-adren ...... LN3 and ubiquitylation by pVHL
@ast
Oxygen-regulated beta(2)-adren ...... LN3 and ubiquitylation by pVHL
@en
Oxygen-regulated beta(2)-adren ...... LN3 and ubiquitylation by pVHL
@en-gb
Oxygen-regulated beta(2)-adren ...... LN3 and ubiquitylation by pVHL
@nl
prefLabel
Oxygen-regulated beta(2)-adren ...... LN3 and ubiquitylation by pVHL
@ast
Oxygen-regulated beta(2)-adren ...... LN3 and ubiquitylation by pVHL
@en
Oxygen-regulated beta(2)-adren ...... LN3 and ubiquitylation by pVHL
@en-gb
Oxygen-regulated beta(2)-adren ...... LN3 and ubiquitylation by pVHL
@nl
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P2860
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P1476
Oxygen-regulated beta(2)-adren ...... LN3 and ubiquitylation by pVHL
@en
P2093
Erin J Whalen
Guohua Fong
Jonathan S Stamler
Kunhong Xiao
Michael T Forrester
Robert J Lefkowitz
Robert S Freeman
P2860
P3181
P356
10.1126/SCISIGNAL.2000444
P407
P577
2009-01-01T00:00:00Z