The parafibromin tumor suppressor protein inhibits cell proliferation by repression of the c-myc proto-oncogene
about
Transcriptional activators enhance polyadenylation of mRNA precursorsEndocrine neoplasms in familial syndromes of hyperparathyroidismGenetic and epigenetic changes in sporadic endocrine tumors: parathyroid tumorsGenomic profiling reveals mutational landscape in parathyroid carcinomasFrequent promoter hypermethylation of the APC and RASSF1A tumour suppressors in parathyroid tumours.Human synthetic lethal inference as potential anti-cancer target gene detectionThe tumor suppressor, parafibromin, mediates histone H3 K9 methylation for cyclin D1 repression.Characterization of a new CDC73 missense mutation that impairs Parafibromin expression and nucleolar localization.Transactivation of microRNA-383 by steroidogenic factor-1 promotes estradiol release from mouse ovarian granulosa cells by targeting RBMS1Clinical and molecular genetics of parathyroid neoplasmsDefective nucleolar localization and dominant interfering properties of a parafibromin L95P missense mutant causing the hyperparathyroidism-jaw tumor syndrome.Cytoplasmic polyadenylation element binding protein is a conserved target of tumor suppressor HRPT2/CDC73.Identification of a role for histone H2B ubiquitylation in noncoding RNA 3'-end formation through mutational analysis of Rtf1 in Saccharomyces cerevisiaeIdentification and functional characterization of three NoLS (nucleolar localisation signals) mutations of the CDC73 gene.Parathyroid carcinoma: current understanding and new insights into gene expression and intraoperative parathyroid hormone kineticsProtein Degradation of RNA Polymerase II-Association Factor 1(PAF1) Is Controlled by CNOT4 and 26S Proteasome.The EIF4EBP3 translational repressor is a marker of CDC73 tumor suppressor haploinsufficiency in a parathyroid cancer syndrome.A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair.Ctr9, a key subunit of PAFc, affects global estrogen signaling and drives ERα-positive breast tumorigenesis.The many roles of the conserved eukaryotic Paf1 complex in regulating transcription, histone modifications, and disease states.Menin mediates epigenetic regulation via histone H3 lysine 9 methylation.CDC73 gene mutations in sporadic ossifying fibroma of the jaws.The Paf1 complex: platform or player in RNA polymerase II transcription?Diagnosis and management of parathyroid cancer.Molecular profiling in primary hyperparathyroidism.The Paf1 complex represses SER3 transcription in Saccharomyces cerevisiae by facilitating intergenic transcription-dependent nucleosome occupancy of the SER3 promoter.Distinct roles of parafibromin in the extracellular environment, cytoplasm and nucleus of osteosarcoma cells.The clinicopathological significances and biological functions of parafibromin expression in head and neck squamous cell carcinomas.GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1.An Overview of Autosomal Dominant Tumour Syndromes with Prominent Features in the Oral and Maxillofacial Region.SHP2 tyrosine phosphatase converts parafibromin/Cdc73 from a tumor suppressor to an oncogenic driver.BET bromodomain inhibitors block growth of pancreatic cancer cells in three-dimensional collagen.PLANT HOMOLOGOUS TO PARAFIBROMIN is a component of the PAF1 complex and assists in regulating expression of genes within H3K27ME3-enriched chromatin.Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome.The roles of parafibromin expression in ovarian epithelial carcinomas: a marker for differentiation and prognosis and a target for gene therapy.The clinicopathological and prognostic significances of CDC73 expression in cancers: a bioinformatics analysis.Bioinformatics analysis of fibroblasts exposed to TGF‑β at the early proliferation phase of wound repair.PAF1 complex component Leo1 helps recruit Drosophila Myc to promoters.Cytoplasmic parafibromin/hCdc73 targets and destabilizes p53 mRNA to control p53-mediated apoptosis.PAF1 complex interactions with SETDB1 mediate promoter H3K9 methylation and transcriptional repression of Hoxa9 and Meis1 in acute myeloid leukemia.
P2860
0aff139afa654a2f6c911bd1ea8e6d89cef628b12d9936b95d537bf05ee6f7db218f6b6c3b705fca3787d6cb2538d31a2874d717a0563c3c2ca7f7495c98176be09365fc4d45ea4a7d5a8d62dd9ab23991c71958ad957b6b72bf403d07267d6df59835e9addb5bd535149995c9637bf5569d1bc55348cfdfdc969fd24369bf1537fb00cd50be4c91d9cf87a9fb1ee70ada8e75108ea312eedc563145b8e176e8fed68a32c794083ddd30b893416d0f63e966ca02
P248
Q24293440-3710F5F1-BFD7-4EFA-990A-79A001A3E243Q26747174-9DE4BB30-B137-4EBD-86A9-0C84D999AF20Q27025359-8DFCC710-AD3C-476A-BFCD-E331DFD7A6B7Q30360213-EB73D309-0783-464B-B231-DE608467D314Q30979173-0EDBB084-B006-403F-B931-56B12BA86245Q33518904-BAA0B89F-DAED-4CAF-9240-29D7EB0B126FQ33608914-30D245B1-F0CF-4052-93CD-AB5DA1CB6FC9Q33632809-AD40B3C1-4AA3-4B03-85A2-C16A0BA335A5Q33636429-21B3B171-A7F3-42AA-BCEB-43D450495FE1Q34125668-62BA7E46-644E-4CC4-A602-948A4D795685Q34993892-DA9AB7AD-D90E-4CE7-8F97-3A8FB709273AQ35029135-4DBF8CC4-9085-4C32-82F0-09F4811178E3Q35065497-06270C86-3888-4CCD-BA54-FEAC98972C64Q35067757-3C767D26-D3C7-43B3-B409-FCA5BC00BF00Q35583695-E330ED83-CF38-4F48-ADE9-79E7B2BACC3FQ35620388-A5166C13-4536-45B8-9D99-AF1121DCE427Q35783618-3496D7E2-3321-4410-B9C3-FF229B59AD91Q36086940-0409AB55-289A-433C-9BF3-C37AF733EC28Q36199639-69023571-E71D-4853-BAD9-D16F2C452B98Q36522035-AFC153CF-5962-4D94-BD98-2B429DAB4E83Q36890205-3A418984-26F6-4FA9-93D9-7921625A7070Q37278906-44FD22E3-C099-48E3-B5DD-DD9A7E2A3177Q37671309-DA48EB07-B7A5-4121-AD69-885F606182C5Q38023142-13D5356F-7E4F-455D-A6BA-AEDD0A22BA20Q38193373-56B80190-8C7B-4F9B-92F5-F57AA0BD081FQ38627903-33261CA2-CC58-4398-8FCB-706652EEADE6Q38761703-01970289-3B21-4331-BCEB-84B5133ECFE4Q38858757-3D47BC83-4D32-44B3-A756-4AA5F2C8A6FBQ38895410-6EDAF344-EE1E-41A4-8D02-B131F5A9C22AQ39097827-5CF9D72C-6559-4178-A5CA-3EBFDC4F3A58Q41908225-70591CA6-B5EF-400E-9725-F908151C6F6BQ42128109-22AFCB52-D637-4E9D-8B88-705C8E97A21EQ43110166-22EEB9BE-E616-46D6-91CC-657F46EC067EQ44004244-48AC7C2A-97E9-4555-AD09-20FDBBE4A573Q45879500-9E101AC3-E306-4FE6-92AB-20C4339820BEQ47130466-F5259D25-EF90-47F0-B173-C518AC55D06CQ47659761-6B877764-CFA0-483D-BFC3-C44D01E87265Q48112980-9B66CD43-8C14-49FD-845C-0FD82325A4AFQ53228284-ECE686F4-A5CE-4908-939B-5C1EFAF69395Q55039489-33161914-9A58-4665-8549-6535FA63452F
P2860
The parafibromin tumor suppressor protein inhibits cell proliferation by repression of the c-myc proto-oncogene
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The parafibromin tumor suppres ...... on of the c-myc proto-oncogene
@ast
The parafibromin tumor suppres ...... on of the c-myc proto-oncogene
@en
The parafibromin tumor suppres ...... on of the c-myc proto-oncogene
@en-gb
The parafibromin tumor suppres ...... on of the c-myc proto-oncogene
@nl
type
label
The parafibromin tumor suppres ...... on of the c-myc proto-oncogene
@ast
The parafibromin tumor suppres ...... on of the c-myc proto-oncogene
@en
The parafibromin tumor suppres ...... on of the c-myc proto-oncogene
@en-gb
The parafibromin tumor suppres ...... on of the c-myc proto-oncogene
@nl
prefLabel
The parafibromin tumor suppres ...... on of the c-myc proto-oncogene
@ast
The parafibromin tumor suppres ...... on of the c-myc proto-oncogene
@en
The parafibromin tumor suppres ...... on of the c-myc proto-oncogene
@en-gb
The parafibromin tumor suppres ...... on of the c-myc proto-oncogene
@nl
P2093
P2860
P921
P3181
P356
P1476
The parafibromin tumor suppres ...... on of the c-myc proto-oncogene
@en
P2093
Jian-Hua Zhang
Leelamma M Panicker
William F Simonds
P2860
P304
P3181
P356
10.1073/PNAS.0710725105
P407
P577
2008-11-11T00:00:00Z