Molecular characterization of human and mouse fatty acid amide hydrolases
about
Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolaseEndocannabinoid signaling in female reproductionA hypothesis about the endogenous analogue of general anesthesiaThe endocannabinoid system as a target for the treatment of cannabis dependenceEvidence against the presence of an anandamide transporterOf mice and (wo)men: factors influencing successful implantation including endocannabinoidsUlcerative colitis induces changes on the expression of the endocannabinoid system in the human colonic tissueX-ray Crystallographic Analysis of α-Ketoheterocycle Inhibitors Bound to a Humanized Variant of Fatty Acid Amide HydrolaseFluoride-Mediated Capture of a Noncovalent Bound State of a Reversible Covalent Enzyme Inhibitor: X-ray Crystallographic Analysis of an Exceptionally Potent α-Ketoheterocycle Inhibitor of Fatty Acid Amide HydrolaseReversible Competitive α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Constraints in the Acyl Side Chain: Orally Active, Long-Acting AnalgesicsRational Design of Fatty Acid Amide Hydrolase Inhibitors That Act by Covalently Bonding to Two Active Site ResiduesCannabinoids, endocannabinoids, and cancerInhibition of FAAH and activation of PPAR: new approaches to the treatment of cognitive dysfunction and drug addictionFatty acid amide hydrolase as a potential therapeutic target for the treatment of pain and CNS disordersEnzymatic pathways that regulate endocannabinoid signaling in the nervous systemKeys to Lipid Selection in Fatty Acid Amide Hydrolase Catalysis: Structural Flexibility, Gating Residues and Multiple Binding PocketsEvidence for distinct roles in catalysis for residues of the serine-serine-lysine catalytic triad of fatty acid amide hydrolaseDeletion of a proline-rich region and a transmembrane domain in fatty acid amide hydrolase.Localisation and function of the endocannabinoid system in the human ovary.Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: synthesis of N-acyl glycinals.Genetic loss of Faah compromises male fertility in mice.Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2.α-Ketoheterocycle inhibitors of fatty acid amide hydrolase: exploration of conformational constraints in the acyl side chain.Interactions of Cannabinoids With Biochemical SubstratesIncorporation of therapeutically modified bacteria into gut microbiota inhibits obesity.Endocannabinoid binding to the cannabinoid receptors: what is known and what remains unknown.The discovery and development of inhibitors of fatty acid amide hydrolase (FAAH).A missense mutation in human fatty acid amide hydrolase associated with problem drug use.Discovery libraries targeting the major enzyme classes: the serine hydrolases.Discovery of MK-4409, a Novel Oxazole FAAH Inhibitor for the Treatment of Inflammatory and Neuropathic Pain.Plant responses to bacterial N-acyl L-homoserine lactones are dependent on enzymatic degradation to L-homoserineLipid profiling reveals tissue-specific differences for ethanolamide lipids in mice lacking fatty acid amide hydrolase.Functional disassociation of the central and peripheral fatty acid amide signaling systems.Microwave Assisted Synthesis of Sodium Sulfonates Precursors of Sulfonyl Chlorides and Fluorides.Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models.Sulfonyl fluoride inhibitors of fatty acid amide hydrolase.The endocannabinoid system and painInhibition of FAAH, TRPV1, and COX2 by NSAID-serotonin conjugates.Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6.'Entourage' effects of N-acyl ethanolamines at human vanilloid receptors. Comparison of effects upon anandamide-induced vanilloid receptor activation and upon anandamide metabolism
P2860
Q24555807-4BCB21C5-37C7-4499-88DB-9E9844AD4432Q24599033-7D0633B3-6628-4D43-83E7-A709B5CD8E9AQ24601737-F504CE7F-3B24-468E-AC0F-517A04BC0E32Q24648135-2A88682E-880A-4B6B-B634-8EFD29D379A9Q24683153-834C7FCF-4FAB-4DBE-98CE-AC25A07B0869Q26992063-24F789C2-92B3-465E-9C6E-A1CA4D86B125Q27342536-64105E96-9DEF-4CB0-AE3D-C7DD0D7A62AEQ27658264-1D416DF4-D6C0-4087-AA18-D7379054F96FQ27667078-17F9AB68-FB4E-4832-A5BC-23273E98EAD6Q27667312-C1C71046-6889-4138-9C7F-B61BE8BAA65FQ27677344-A14CB44B-227A-4749-8BDF-5E080417732BQ27694715-F33914E7-2BBF-45A6-90E4-85F893F6C05BQ28283718-2856781A-84F5-4373-AAA9-FEC6213DFDD9Q28285103-DB696955-BBF1-49D4-BB1D-75DD15CF50B3Q28390932-8E77EFBE-2FD4-426D-A745-D38E104813D3Q28548681-DD899716-76E6-4AFC-A79D-748D66FBDB49Q28570492-8B551296-FAC3-413E-B0F2-F946BCB344C5Q30175394-846F06C4-A915-4385-A8C6-7031A2B8B785Q33411754-898FF330-566E-4C9C-9C4B-EF9F5D2904EFQ33560137-96A69A75-80E3-4903-AF86-99247D388AA0Q33583700-2DF83043-DAE0-47A1-8E60-0781599CF7DCQ33594073-EA8212B9-5DE7-4758-93AD-BE1C27AAEC06Q33644120-08654AC3-1103-489A-A70C-AFA06FADFAC3Q33758351-24A54E04-2FE9-4B27-A357-116A64246859Q33944259-119845B9-CC88-4259-A79F-5D091E58A1B5Q33997873-82EF67E2-A4DE-40D3-89EF-6608A9AB1634Q34027721-2B42E447-D0FE-4A7F-90C2-5924002632AEQ34032872-71226CC1-2750-4153-B17E-97EB750D8593Q34036280-E3719841-26E3-4D47-9718-D6CFC4F00FA0Q34041284-FC764E41-4D7E-403B-A91C-6FCD22411FBCQ34061224-453FE697-4C6E-4C3B-B1C1-3C6AB91A1798Q34150144-C80C4A64-00BB-4C83-8751-D9E8DC7905AFQ34332678-41BDAE50-6751-4B43-BF3C-426BBCF082A0Q34363783-78AA17F3-4B48-4049-B815-A944FEBD0AF6Q34390806-802404AB-018C-4AFE-B955-8F43FA28E922Q34452685-7C4B878D-2017-443E-AC2C-EA8B16B06943Q34612917-17ACD3C6-9A94-4B71-BF15-0E7CAD7373A0Q34644485-6C35500A-69F2-44E6-A2F9-11FBB8E16E8CQ34856974-44DA8819-1CC8-471A-BCC9-8EEDDEBBD1EDQ35044394-AAAADA66-0D4B-4E4B-9626-80F9503E56F8
P2860
Molecular characterization of human and mouse fatty acid amide hydrolases
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Molecular characterization of human and mouse fatty acid amide hydrolases
@ast
Molecular characterization of human and mouse fatty acid amide hydrolases
@en
Molecular characterization of human and mouse fatty acid amide hydrolases
@en-gb
Molecular characterization of human and mouse fatty acid amide hydrolases
@nl
type
label
Molecular characterization of human and mouse fatty acid amide hydrolases
@ast
Molecular characterization of human and mouse fatty acid amide hydrolases
@en
Molecular characterization of human and mouse fatty acid amide hydrolases
@en-gb
Molecular characterization of human and mouse fatty acid amide hydrolases
@nl
prefLabel
Molecular characterization of human and mouse fatty acid amide hydrolases
@ast
Molecular characterization of human and mouse fatty acid amide hydrolases
@en
Molecular characterization of human and mouse fatty acid amide hydrolases
@en-gb
Molecular characterization of human and mouse fatty acid amide hydrolases
@nl
P2860
P921
P356
P1476
Molecular characterization of human and mouse fatty acid amide hydrolases
@en
P2093
B F Cravatt
P2860
P304
P356
10.1073/PNAS.94.6.2238
P407
P577
1997-03-18T00:00:00Z