NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is the mammalian homolog of the mitochondrial enzyme encoded by the yeast MIS1 gene
about
Human mitochondrial C1-tetrahydrofolate synthase: gene structure, tissue distribution of the mRNA, and immunolocalization in Chinese hamster ovary callsThe X-ray structure of the NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase fromSaccharomyces cerevisiaeMagnesium and phosphate ions enable NAD binding to methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase.Biochemical and genetic analysis of methylenetetrahydrofolate reductase in Leishmania metabolism and virulence.Mitochondrial MTHFD2L is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase expressed in both adult and embryonic tissues.Mitochondrial NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is essential for embryonic developmentDisruption of the mthfd1 gene reveals a monofunctional 10-formyltetrahydrofolate synthetase in mammalian mitochondria.Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage.The enzymes of the 10-formyl-tetrahydrofolate synthetic pathway are found exclusively in the cytosol of the trypanosomatid parasite Leishmania major.One-Carbon Metabolism in Health and Disease.High-throughput RNAi screening for novel modulators of vimentin expression identifies MTHFD2 as a regulator of breast cancer cell migration and invasion.Mammalian fibroblasts lacking mitochondrial NAD+-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase are glycine auxotrophs.Homocysteine-dependent alterations in mitochondrial gene expression, function and structure. Homocysteine and H2O2 act synergistically to enhance mitochondrial damage.NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is targeted to the cytoplasm in insect cell lines.Human mitochondrial MTHFD2 is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase.MTHFD2; D2L oxidise 5;10-methylene-THF to 5;10-methenyl-THFMTHFD2; D2L oxidise 5;10-methenyl-THF to 10-formyl-THF
P2860
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P2860
NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is the mammalian homolog of the mitochondrial enzyme encoded by the yeast MIS1 gene
description
1993 nî lūn-bûn
@nan
1993 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
NAD-dependent methylenetetrahy ...... encoded by the yeast MIS1 gene
@ast
NAD-dependent methylenetetrahy ...... encoded by the yeast MIS1 gene
@en
NAD-dependent methylenetetrahy ...... encoded by the yeast MIS1 gene
@en-gb
NAD-dependent methylenetetrahy ...... encoded by the yeast MIS1 gene
@nl
type
label
NAD-dependent methylenetetrahy ...... encoded by the yeast MIS1 gene
@ast
NAD-dependent methylenetetrahy ...... encoded by the yeast MIS1 gene
@en
NAD-dependent methylenetetrahy ...... encoded by the yeast MIS1 gene
@en-gb
NAD-dependent methylenetetrahy ...... encoded by the yeast MIS1 gene
@nl
prefLabel
NAD-dependent methylenetetrahy ...... encoded by the yeast MIS1 gene
@ast
NAD-dependent methylenetetrahy ...... encoded by the yeast MIS1 gene
@en
NAD-dependent methylenetetrahy ...... encoded by the yeast MIS1 gene
@en-gb
NAD-dependent methylenetetrahy ...... encoded by the yeast MIS1 gene
@nl
P356
P1433
P1476
NAD-dependent methylenetetrahy ...... encoded by the yeast MIS1 gene
@en
P2093
R E MacKenzie
P304
P356
10.1021/BI00092A022
P407
P577
1993-10-19T00:00:00Z