Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation
about
Systematic identification of regulatory proteins critical for T-cell activationLarge-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genesDAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositidesSH2-Balpha is an insulin-receptor adapter protein and substrate that interacts with the activation loop of the insulin-receptor kinaseThe adapter protein APS associates with the multifunctional docking sites Tyr-568 and Tyr-936 in c-KitSH2-B is required for both male and female reproductionEnigma interacts with adaptor protein with PH and SH2 domains to control insulin-induced actin cytoskeleton remodeling and glucose transporter 4 translocationEnhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein, LnkDirect interaction of nerve growth factor receptor, TrkA, with non-receptor tyrosine kinase, c-Abl, through the activation loopMDM2 interacts with MDMX through their RING finger domainsLigand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7A PDZ domain protein interacts with the C-terminal tail of the insulin-like growth factor-1 receptor but not with the insulin receptorThe adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathwaysRegulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, LnkFiz1, a novel zinc finger protein interacting with the receptor tyrosine kinase Flt3STAP-2/BKS, an adaptor/docking protein, modulates STAT3 activation in acute-phase response through its YXXQ motifSH2B1 and IRSp53 proteins promote the formation of dendrites and dendritic branchesFMIP, a novel Fms-interacting protein, affects granulocyte/macrophage differentiationIdentification of the APS protein as a novel insulin receptor substrateRegulation of hematopoietic development in the aorta-gonad-mesonephros region mediated by Lnk adaptor proteinIncreased numbers of B-1 cells and enhanced responses against TI-2 antigen in mice lacking APS, an adaptor molecule containing PH and SH2 domainsTemporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiationMolecular definition of the germinal centre stage of B-cell differentiation.Four PSM/SH2-B alternative splice variants and their differential roles in mitogenesis.Asb6, an adipocyte-specific ankyrin and SOCS box protein, interacts with APS to enable recruitment of elongins B and C to the insulin receptor signaling complex.Negative regulation of receptor tyrosine kinase signals.The Drosophila SH2B family adaptor Lnk acts in parallel to chico in the insulin signaling pathway.Recent advances in the genetics of systemic lupus erythematosus.SH2B1 regulation of energy balance, body weight, and glucose metabolism.SH2-B family members differentially regulate JAK family tyrosine kinases.Adaptor protein APS binds the NH2-terminal autoinhibitory domain of guanine nucleotide exchange factor Vav3 and augments its activity.Lnk-dependent axis of SCF-cKit signal for osteogenesis in bone fracture healing.IL-4 signaling is regulated through the recruitment of phosphatases, kinases, and SOCS proteins to the receptor complex.The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinases.Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis.A small interfering RNA targeting Lnk accelerates bone fracture healing with early neovascularization.Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK.Neuronal SH2B1 is essential for controlling energy and glucose homeostasis.LNK (SH2B3) is a key regulator of integrin signaling in endothelial cells and targets α-parvin to control cell adhesion and migration.Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice.
P2860
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P2860
Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation
description
1997 nî lūn-bûn
@nan
1997 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Cloning and characterization o ...... on B-cell receptor stimulation
@ast
Cloning and characterization o ...... on B-cell receptor stimulation
@en
Cloning and characterization o ...... on B-cell receptor stimulation
@en-gb
Cloning and characterization o ...... on B-cell receptor stimulation
@nl
type
label
Cloning and characterization o ...... on B-cell receptor stimulation
@ast
Cloning and characterization o ...... on B-cell receptor stimulation
@en
Cloning and characterization o ...... on B-cell receptor stimulation
@en-gb
Cloning and characterization o ...... on B-cell receptor stimulation
@nl
prefLabel
Cloning and characterization o ...... on B-cell receptor stimulation
@ast
Cloning and characterization o ...... on B-cell receptor stimulation
@en
Cloning and characterization o ...... on B-cell receptor stimulation
@en-gb
Cloning and characterization o ...... on B-cell receptor stimulation
@nl
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P921
P356
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Cloning and characterization o ...... on B-cell receptor stimulation
@en
P2093
P2888
P356
10.1038/SJ.ONC.1201163
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P577
1997-07-03T00:00:00Z
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P6179
1035846331