about
Transthyretin and the brain re-visited: is neuronal synthesis of transthyretin protective in Alzheimer's disease?BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2Generation and initial characterization of FDD knock in miceSpecific chaperones and regulatory domains in control of amyloid formation.Differences in memory development among C57BL/6NCrl, 129S2/SvPasCrl, and FVB/NCrl mice after delay and trace fear conditioning.Viral transduction of the neonatal brain delivers controllable genetic mosaicism for visualising and manipulating neuronal circuits in vivo.Non-sex specific genes associated with the secondary mitotic period of primordial germ cell proliferation in the gonads of embryonic rainbow trout (Oncorhynchus mykiss).Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease.Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease.Danish dementia mice suggest that loss of function and not the amyloid cascade causes synaptic plasticity and memory deficitsHippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo.Memory deficits due to familial British dementia BRI2 mutation are caused by loss of BRI2 function rather than amyloidosis.Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition.Generalised Anxiety Disorder--A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression.Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice.Memory deficits of British dementia knock-in mice are prevented by Aβ-precursor protein haploinsufficiency.A Common Phenotype Polymorphism in Mammalian Brains Defined by Concomitant Production of Prolactin and Growth Hormone.A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomersCerebral amyloidosis: amyloid subunits, mutants and phenotypes.Anti-Aβ single-chain variable fragment antibodies exert synergistic neuroprotective activities in Drosophila models of Alzheimer's diseaseHippocampal expression of murine IL-4 results in exacerbation of amyloid depositionmicroRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the BrainMurine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits.5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of Alzheimer disease.Neuropathologically defined subtypes of Alzheimer's disease differ significantly from neurofibrillary tangle-predominant dementia.Oxidative stress and mitochondria-mediated cell death mechanisms triggered by the familial Danish dementia ADan amyloidOverlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains.Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis.The influence of 5-lipoxygenase on Alzheimer's disease-related tau pathology: in vivo and in vitro evidence.Amelogenins: Multi-Functional Enamel Matrix Proteins and Their Binding PartnersIFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice.Holdase activity of secreted Hsp70 masks amyloid-β42 neurotoxicity in DrosophilaAAV1/2-mediated CNS gene delivery of dominant-negative CCL2 mutant suppresses gliosis, beta-amyloidosis, and learning impairment of APP/PS1 mice.BRI2 inhibits amyloid beta-peptide precursor protein processing by interfering with the docking of secretases to the substrate.The effect of brief neonatal cryoanesthesia on physical development and adult cognitive function in mice.Amyloid peptides ABri and ADan show differential neurotoxicity in transgenic Drosophila models of familial British and Danish dementia.Animal models of human amyloidoses: are transgenic mice worth the time and trouble?BRI2 interacts with BACE1 and regulates its cellular levels by promoting its degradation and reducing its mRNA levels.BRICHOS domain associated with lung fibrosis, dementia and cancer--a chaperone that prevents amyloid fibril formation?Cerebrospinal fluid and blood biomarkers of neuroaxonal damage in multiple sclerosis.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
BRI2 (ITM2b) inhibits Abeta deposition in vivo
@ast
BRI2 (ITM2b) inhibits Abeta deposition in vivo
@en
BRI2 (ITM2b) inhibits Abeta deposition in vivo
@en-gb
BRI2 (ITM2b) inhibits Abeta deposition in vivo
@nl
type
label
BRI2 (ITM2b) inhibits Abeta deposition in vivo
@ast
BRI2 (ITM2b) inhibits Abeta deposition in vivo
@en
BRI2 (ITM2b) inhibits Abeta deposition in vivo
@en-gb
BRI2 (ITM2b) inhibits Abeta deposition in vivo
@nl
prefLabel
BRI2 (ITM2b) inhibits Abeta deposition in vivo
@ast
BRI2 (ITM2b) inhibits Abeta deposition in vivo
@en
BRI2 (ITM2b) inhibits Abeta deposition in vivo
@en-gb
BRI2 (ITM2b) inhibits Abeta deposition in vivo
@nl
P2093
P2860
P1476
BRI2 (ITM2b) inhibits Abeta deposition in vivo
@en
P2093
Brenda D Moore
Christophe Verbeeck
Craig W Zwizinski
Fanggeng Zou
Fredrick J Troendle
Karen Jansen West
Kayleigh Wagg
Leilani Sonoda
Lisa Smithson
Maralyssa Bann
P2860
P304
P356
10.1523/JNEUROSCI.0891-08.2008
P407
P577
2008-06-04T00:00:00Z