Intracellular localization of 8-oxo-dGTPase in human cells, with special reference to the role of the enzyme in mitochondria
about
Functional significance of the conserved residues for the 23-residue module among MTH1 and MutT family proteinsAn oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stressRegulation of mitochondrial D-loops by transcription factor A and single-stranded DNA-binding proteinThe maintenance of mitochondrial DNA integrity--critical analysis and updateCellular levels of 8-oxoguanine in either DNA or the nucleotide pool play pivotal roles in carcinogenesis and survival of cancer cellsMitochondrial DNA damage and its consequences for mitochondrial gene expressionInactivation of Saccharomyces cerevisiae OGG1 DNA repair gene leads to an increased frequency of mitochondrial mutants.p32 protein, a splicing factor 2-associated protein, is localized in mitochondrial matrix and is functionally important in maintaining oxidative phosphorylation.Structure of human MTH1, a Nudix family hydrolase that selectively degrades oxidized purine nucleoside triphosphatesExpression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAsMitochondrial import of PKCepsilon is mediated by HSP90: a role in cardioprotection from ischaemia and reperfusion injuryA role for oxidized DNA precursors in Huntington's disease-like striatal neurodegenerationMyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survivalIdentification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondriaEosinophil extracellular trap cell death-derived DNA traps: Their presence in secretions and functional attributes.Heterogeneous nuclear ribonucleoprotein K protein associates with multiple mitochondrial transcripts within the organelle.Human APE2 protein is mostly localized in the nuclei and to some extent in the mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigenThe role of mitochondrial DNA mutations in mammalian agingRepair of mtDNA in vertebrates.Purification and characterization of a mammalian homolog of Escherichia coli MutY mismatch repair protein from calf liver mitochondria.Urinary 8-oxo-2'-deoxyguanosine--source, significance and supplements.Involvement of oxidatively damaged DNA and repair in cancer development and aging.Drosophila TAP/p32 is a core histone chaperone that cooperates with NAP-1, NLP, and nucleophosmin in sperm chromatin remodeling during fertilization.Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity.The oxidized deoxynucleoside triphosphate pool is a significant contributor to genetic instability in mismatch repair-deficient cellsFunctional regulation of FEN1 nuclease and its link to cancerA novel assay of 8-oxo-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) activity in cultured cells and its use for evaluation of cadmium(II) inhibition of this activity.Human mitochondrial DNA is packaged with TFAM.Mitochondrial oxidative stress and mitochondrial DNA.Human REV3 DNA Polymerase Zeta Localizes to Mitochondria and Protects the Mitochondrial Genome.The defense mechanisms in mammalian cells against oxidative damage in nucleic acids and their involvement in the suppression of mutagenesis and cell death.The DNA polymerase gamma Y955C disease variant associated with PEO and parkinsonism mediates the incorporation and translesion synthesis opposite 7,8-dihydro-8-oxo-2'-deoxyguanosine.Repair of mitochondrial DNA in aging and carcinogenesis.8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions.Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase gamma replication fidelity.'To repair or not to repair - no longer a question': repair of mitochondrial DNA shielding against age and cancer.Ribonucleotide reductase association with mammalian liver mitochondria.Mitochondrial DNA repair in aging and diseasePrognostic impact of MutT homolog-1 expression on esophageal squamous cell carcinoma.Significance of the conserved amino acid sequence for human MTH1 protein with antimutator activity.
P2860
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P2860
Intracellular localization of 8-oxo-dGTPase in human cells, with special reference to the role of the enzyme in mitochondria
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
name
Intracellular localization of ...... of the enzyme in mitochondria
@ast
Intracellular localization of ...... of the enzyme in mitochondria
@en
Intracellular localization of ...... of the enzyme in mitochondria
@en-gb
Intracellular localization of ...... of the enzyme in mitochondria
@nl
type
label
Intracellular localization of ...... of the enzyme in mitochondria
@ast
Intracellular localization of ...... of the enzyme in mitochondria
@en
Intracellular localization of ...... of the enzyme in mitochondria
@en-gb
Intracellular localization of ...... of the enzyme in mitochondria
@nl
prefLabel
Intracellular localization of ...... of the enzyme in mitochondria
@ast
Intracellular localization of ...... of the enzyme in mitochondria
@en
Intracellular localization of ...... of the enzyme in mitochondria
@en-gb
Intracellular localization of ...... of the enzyme in mitochondria
@nl
P2093
P921
P356
P1476
Intracellular localization of ...... of the enzyme in mitochondria
@en
P2093
K Takeshige
M Furuichi
M Sekiguchi
T Fujiwara
P304
14659-14665
P356
10.1074/JBC.270.24.14659
P407
P577
1995-06-01T00:00:00Z