Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase gamma replication fidelity.
about
The maintenance of mitochondrial DNA integrity--critical analysis and updateCellular levels of 8-oxoguanine in either DNA or the nucleotide pool play pivotal roles in carcinogenesis and survival of cancer cellsMitochondrial DNA damage and its consequences for mitochondrial gene expressionNucleotide salvage deficiencies, DNA damage and neurodegenerationOxidation of the guanine nucleotide pool underlies cell death by bactericidal antibioticsMycobacterial MazG is a novel NTP pyrophosphohydrolase involved in oxidative stress responseAnalysis of enzyme kinetic data for mtDNA replication.Antibiotics induce redox-related physiological alterations as part of their lethality.Aging and HIV/AIDS: pathogenetic role of therapeutic side effectsNucleoside triphosphate pool asymmetry in mammalian mitochondriaUncovering the polymerase-induced cytotoxicity of an oxidized nucleotideA review comparing deoxyribonucleoside triphosphate (dNTP) concentrations in the mitochondrial and cytoplasmic compartments of normal and transformed cellsAcademic life: the whole package.The awakening of an advanced malignant cancer: an insult to the mitochondrial genomeEffect of the Y955C mutation on mitochondrial DNA polymerase nucleotide incorporation efficiency and fidelity.Effects of a mitochondrial mutator mutation in yeast POS5 NADH kinase on mitochondrial nucleotides.Nucleotide binding interactions modulate dNTP selectivity and facilitate 8-oxo-dGTP incorporation by DNA polymerase lambda.Oxidized dNTPs and the OGG1 and MUTYH DNA glycosylases combine to induce CAG/CTG repeat instability.Deoxyribonucleotides as genetic and metabolic regulatorsDeoxyribonucleotide metabolism, mutagenesis and cancer.Oxidative guanine base damage regulates human telomerase activity.The Deoxynucleoside Triphosphate Triphosphohydrolase Activity of SAMHD1 Protein Contributes to the Mitochondrial DNA Depletion Associated with Genetic Deficiency of Deoxyguanosine Kinase.ATP insertion opposite 8-oxo-deoxyguanosine by Pol4 mediates error-free tolerance in Schizosaccharomyces pombe.DNA repair and the origins of urinary oxidized 2'-deoxyribonucleosides.The m6A methylation perturbs the Hoogsteen pairing-guided incorporation of an oxidized nucleotide.Biochemical and structural studies of Mycobacterium smegmatis MutT1, a sanitization enzyme with unusual modes of association.Modified nucleoside triphosphates exist in mammals.
P2860
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P2860
Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase gamma replication fidelity.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Trace amounts of 8-oxo-dGTP in ...... se gamma replication fidelity.
@ast
Trace amounts of 8-oxo-dGTP in ...... se gamma replication fidelity.
@en
type
label
Trace amounts of 8-oxo-dGTP in ...... se gamma replication fidelity.
@ast
Trace amounts of 8-oxo-dGTP in ...... se gamma replication fidelity.
@en
prefLabel
Trace amounts of 8-oxo-dGTP in ...... se gamma replication fidelity.
@ast
Trace amounts of 8-oxo-dGTP in ...... se gamma replication fidelity.
@en
P2860
P50
P356
P1476
Trace amounts of 8-oxo-dGTP in ...... ase gamma replication fidelity
@en
P2093
Christopher K Mathews
P2860
P304
P356
10.1093/NAR/GKN062
P407
P577
2008-02-14T00:00:00Z