Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
about
Analysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunitsDriving with no brakes: molecular pathophysiology of Kv7 potassium channelsWorking model for the structural basis for KCNE1 modulation of the KCNQ1 potassium channel.Differential modulations of KCNQ1 by auxiliary proteins KCNE1 and KCNE2Mechanisms of disease pathogenesis in long QT syndrome type 5Identification of a protein-protein interaction between KCNE1 and the activation gate machinery of KCNQ1KCNE1 remodels the voltage sensor of Kv7.1 to modulate channel function.Allosteric features of KCNQ1 gating revealed by alanine scanning mutagenesis.LQT1 mutations in KCNQ1 C-terminus assembly domain suppress IKs using different mechanisms.Domain-domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channelKCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue.Regulation of Voltage-Activated K(+) Channel Gating by Transmembrane β Subunits.[Ca2+]i elevation and oxidative stress induce KCNQ1 protein translocation from the cytosol to the cell surface and increase slow delayed rectifier (IKs) in cardiac myocytes.Structural basis for K(V)7.1-KCNE(x) interactions in the I(Ks) channel complex.Gating-related molecular motions in the extracellular domain of the IKs channel: implications for IKs channelopathy.The voltage-gated channel accessory protein KCNE2: multiple ion channel partners, multiple ways to long QT syndrome.Cytoplasmic domains and voltage-dependent potassium channel gating.The KCNE Tango - How KCNE1 Interacts with Kv7.1.cAMP-dependent regulation of IKs single-channel kinetics.Voltage-Dependent Gating: Novel Insights from KCNQ1 Channels.Molecular Pathophysiology of Congenital Long QT Syndrome.Competition of calcified calmodulin N lobe and PIP2 to an LQT mutation site in Kv7.1 channel.Does a physiological role for KCNE subunits exist in the immune system?KCNQ1 channels do not undergo concerted but sequential gating transitions in both the absence and the presence of KCNE1 proteinCa(2+)-Calmodulin and PIP2 interactions at the proximal C-terminus of Kv7 channels.A Calmodulin C-Lobe Ca2+-Dependent Switch Governs Kv7 Channel Function.
P2860
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P2860
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
@ast
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
@en
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
@en-gb
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
@nl
type
label
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
@ast
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
@en
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
@en-gb
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
@nl
prefLabel
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
@ast
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
@en
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
@en-gb
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
@nl
P2093
P2860
P356
P1433
P1476
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
@en
P2093
Asher Peretz
Bernard Attali
Dana Shaham
Enbal Ben-Tal Cohen
Joel A Hirsch
Liora Shamgar
Olaf Pongs
Reuven Wiener
P2860
P304
P356
10.1038/EMBOJ.2009.157
P407
P50
P577
2009-06-11T00:00:00Z