A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants
about
A novel human RasGAP-like gene that maps within the prostate cancer susceptibility locus at chromosome 1q25Cloning and characterization of PHIP, a novel insulin receptor substrate-1 pleckstrin homology domain interacting proteinIdentification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiaeA novel RASA1 mutation causing capillary malformation-arteriovenous malformation (CM-AVM) presenting during pregnancyTyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transductionDi-Ras, a distinct subgroup of ras family GTPases with unique biochemical propertiesIdentification of amino acid residues of Ras protein that are essential for signal-transducing activity but not for enhancement of GTPase activity by GAPThe N-terminal region of GAP regulates cytoskeletal structure and cell adhesionLy-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytesp190-B, a new member of the Rho GAP family, and Rho are induced to cluster after integrin cross-linkingExpression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiaePurification and N-terminal sequence of the p21rho GTPase-activating protein, rho GAPCapillary malformation-arteriovenous malformation, a new clinical and genetic disorder caused by RASA1 mutationsADP-ribosylation factor is functionally and physically associated with the Golgi complexInactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Rasp21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating proteinsar1, a gene from Schizosaccharomyces pombe encoding a protein that regulates ras1Molecular features of the viral and cellular Src kinases involved in interactions with the GTPase-activating protein.Molecular cloning and expression of a G25K cDNA, the human homolog of the yeast cell cycle gene CDC42Interactions of phosphatidylinositol kinase, GTPase-activating protein (GAP), and GAP-associated proteins with the colony-stimulating factor 1 receptorMolecular cloning and characterization of a novel type of regulatory protein (GDI) for smg p25A, a ras p21-like GTP-binding proteinRetroviral oncogenes: a historical primerRas-catalyzed hydrolysis of GTP: a new perspective from model studiesPurification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition methodInteraction of activated Ras with Raf-1 alone may be sufficient for transformation of rat2 cellsStructure-based assignment of the biochemical function of a hypothetical protein: a test case of structural genomicsInteraction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulationRheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signalingPhosphorylation site of NtrC, a protein phosphatase whose covalent intermediate activates transcriptionMicroRNAs mediated regulation of MAPK signaling pathways in chronic myeloid leukemiaK-Ras protein as a drug targetGuanosine triphosphatase stimulation of oncogenic Ras mutantsRefined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysisK-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactionsMutations in cell division cycle genes CDC36 and CDC39 activate the Saccharomyces cerevisiae mating pheromone response pathway.IRA1, an inhibitory regulator of the RAS-cyclic AMP pathway in Saccharomyces cerevisiae.IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein.Two new members of a family of Ypt/Rab GTPase activating proteins. Promiscuity of substrate recognition.GTP hydrolysis is not important for Ypt1 GTPase function in vesicular transport.Overexpression of RPI1, a novel inhibitor of the yeast Ras-cyclic AMP pathway, down-regulates normal but not mutationally activated ras function.
P2860
Q22008617-9F666AC1-8CD8-4B28-8C2A-6134C4E2E18AQ24290359-0B8D8332-901B-4C95-A6C5-0C72C6463651Q24293058-4FC51100-9F64-4FC5-A798-9843C9AF221FQ24293294-D30B4083-A945-4CDE-AF01-7F2054733187Q24303984-44ECFFFE-16B7-4A02-9AD3-BE13B3208C10Q24305223-2AB17BDC-057F-4BDA-B02A-F4A7A9F479CAQ24310635-A892EA78-1254-40B3-96A4-9E52B1B89A3AQ24310756-6311C23B-D802-4896-8EA5-5247F2E27254Q24311993-2DD015C6-CAF6-4CDE-B99F-4858CC36BDC4Q24313690-3664452A-160E-45A4-96F3-89A07A1F54A6Q24314732-1B49DDC9-938C-4F5B-B7A3-D2EBE09DE215Q24529572-7B844E44-DB13-429C-9741-1B6ADDC33CDFQ24532144-278E4CEF-5F4D-4A0E-A9D1-5D44DB354B17Q24559656-BF441BBF-B51A-4203-9ECE-85846FE420D7Q24562679-3B9D50AC-9274-45AC-BD42-B2FBF088D1F9Q24563005-90C9679F-72A7-49FD-BA85-187CC8F90050Q24595034-9DF1BB54-B924-4373-A493-18FB1ACE31EBQ24596400-9FBE624E-3AF7-4F28-9623-1D587B8A9FA4Q24596620-2165F9D9-016F-45D3-A33A-F6788E9B7FDFQ24597241-4E4D2554-E984-4BD7-BA7B-B5C86C959E0EQ24598539-6988A3FB-992C-42BE-B682-61263E6E54FEQ24611142-A19DC0DE-B0CA-442C-91FC-93DAB8B50893Q24630231-66FD6504-9D32-4A5F-8CBA-017F59E3396CQ24631695-413DDB3F-4FBA-42AD-A95D-A1A9B2C59A43Q24646299-DC728166-2896-4E0B-8A57-DC01E0D5C0E3Q24651065-DF268181-94BE-4F3D-B9C7-05447AB3E16EQ24657277-2ACB4CDF-FCA4-4BB0-A311-0398AEE69F8AQ24672005-F849D864-CFAC-4984-B8E9-64B584A0C6FAQ24684197-E09304FC-F67A-4A8B-9775-AA500AD83D82Q26766288-50431EBA-7D89-4855-8DFA-E5C7C557506FQ26766684-7416D1D5-4623-42D8-940E-2FD97EDA5FD0Q27618496-33E0CCD5-DDF7-4291-A96A-5A3EA90CC3BFQ27674619-3EF2266A-2DAA-4962-94EB-2120DFF804DFQ27680654-38DE191A-D77F-441A-82DF-59CA263D4E60Q27930331-1DB0C0BF-A4A9-4E57-A67D-2389F686AA74Q27932316-37246E69-A4BF-49EA-8C8B-8BD8FBFF452BQ27934455-BC9DBC6D-8DBC-4CEC-B291-3A30EB77D861Q27934729-CDF80CE2-A14B-402A-BD5C-522661CE30AAQ27935896-DA5842AC-5722-4C59-848A-C41900C85D81Q27937085-27B7A7DE-4FC5-4D21-9527-46E260B055D4
P2860
A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants
description
1987 nî lūn-bûn
@nan
1987 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
A cytoplasmic protein stimulat ...... s not affect oncogenic mutants
@ast
A cytoplasmic protein stimulat ...... s not affect oncogenic mutants
@en
A cytoplasmic protein stimulat ...... s not affect oncogenic mutants
@en-gb
A cytoplasmic protein stimulat ...... s not affect oncogenic mutants
@nl
type
label
A cytoplasmic protein stimulat ...... s not affect oncogenic mutants
@ast
A cytoplasmic protein stimulat ...... s not affect oncogenic mutants
@en
A cytoplasmic protein stimulat ...... s not affect oncogenic mutants
@en-gb
A cytoplasmic protein stimulat ...... s not affect oncogenic mutants
@nl
prefLabel
A cytoplasmic protein stimulat ...... s not affect oncogenic mutants
@ast
A cytoplasmic protein stimulat ...... s not affect oncogenic mutants
@en
A cytoplasmic protein stimulat ...... s not affect oncogenic mutants
@en-gb
A cytoplasmic protein stimulat ...... s not affect oncogenic mutants
@nl
P3181
P356
P1433
P1476
A cytoplasmic protein stimulat ...... s not affect oncogenic mutants
@en
P2093
P3181
P356
10.1126/SCIENCE.2821624
P407
P577
1987-10-23T00:00:00Z