Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae
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Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for RasHuman SEC13Rp functions in yeast and is located on transport vesicles budding from the endoplasmic reticulumStimulation of Ras guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) upon tyrosine phosphorylation by the Cdc42-regulated kinase ACK1Insulin-stimulated disassociation of the SOS-Grb2 complexPlatelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell typesRas oncogenes: split personalitiesRas history: The saga continues.How Genetics Has Helped Piece Together the MAPK Signaling Pathway.Dematin interacts with the Ras-guanine nucleotide exchange factor Ras-GRF2 and modulates mitogen-activated protein kinase pathways.Regulation of Neuronal Function by Ras-GRF Exchange Factors.Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity.G protein beta gamma subunit-dependent Rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm)Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells.Mitogenic activation of the Ras guanine nucleotide exchange factor in NIH 3T3 cells involves protein tyrosine phosphorylationGTP-dependent association of Raf-1 with Ha-Ras: identification of Raf as a target downstream of Ras in mammalian cells.The Ras-specific exchange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1Probing the role of loop 2 in Ras function with unnatural amino acids.Identification of residues critical for Ras(17N) growth-inhibitory phenotype and for Ras interaction with guanine nucleotide exchange factors.Two types of RAS mutants that dominantly interfere with activators of RAS.Regulated and constitutive activity by CDC25Mm (GRF), a Ras-specific exchange factorRas and Rho small G proteins: insights from the Schizophyllum commune genome sequence and comparisons to other fungi.Induction of rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) following phosphorylation by the nonreceptor tyrosine kinase Src.Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo.Identification of residues of the H-ras protein critical for functional interaction with guanine nucleotide exchange factorsEpidermal growth factor regulates the exchange rate of guanine nucleotides on p21ras in fibroblasts.Maintenance of CDC42 GDP-bound state by Rho-GDI inhibits MAP kinase activation by the exchange factor Ras-GRF. evidence for Ras-GRF function being inhibited by Cdc42-GDP but unaffected by CDC42-GTP.The Rho family GTPase Cdc42 regulates the activation of Ras/MAP kinase by the exchange factor Ras-GRF.Ras-guanine-nucleotide-releasing factors 1 and 2 interact with PLCγ at focal adhesions to enable IL-1-induced Ca(2+) signalling, ERK activation and MMP-3 expression.The requirement of Ras and Rap1 for the activation of ERKs by cAMP, PACAP, and KCl in cerebellar granule cells.The Yeast Saccharomyces cerevisiae as a Model for Understanding RAS Proteins and their Role in Human Tumorigenesis.
P2860
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P2860
Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae
description
1992 nî lūn-bûn
@nan
1992 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Identification of a mammalian ...... ne of Saccharomyces cerevisiae
@ast
Identification of a mammalian ...... ne of Saccharomyces cerevisiae
@en
Identification of a mammalian ...... ne of Saccharomyces cerevisiae
@en-gb
Identification of a mammalian ...... ne of Saccharomyces cerevisiae
@nl
type
label
Identification of a mammalian ...... ne of Saccharomyces cerevisiae
@ast
Identification of a mammalian ...... ne of Saccharomyces cerevisiae
@en
Identification of a mammalian ...... ne of Saccharomyces cerevisiae
@en-gb
Identification of a mammalian ...... ne of Saccharomyces cerevisiae
@nl
prefLabel
Identification of a mammalian ...... ne of Saccharomyces cerevisiae
@ast
Identification of a mammalian ...... ne of Saccharomyces cerevisiae
@en
Identification of a mammalian ...... ne of Saccharomyces cerevisiae
@en-gb
Identification of a mammalian ...... ne of Saccharomyces cerevisiae
@nl
P2093
P2860
P921
P356
P1476
Identification of a mammalian ...... ne of Saccharomyces cerevisiae
@en
P2093
C Dasgupta
D McKinney
E Gonzales
R D Mosteller
P2860
P304
P356
10.1073/PNAS.89.15.7100
P407
P577
1992-08-01T00:00:00Z