Overexpression of an enzymically inactive interleukin-1-receptor-associated kinase activates nuclear factor-kappaB
about
Pellino proteins are more than scaffold proteins in TLR/IL-1R signalling: a role as novel RING E3-ubiquitin-ligasesIRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinaseInterleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathwayLys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activationIRAK signalling in cancerEssential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signalingIdentification of two major sites in the type I interleukin-1 receptor cytoplasmic region responsible for coupling to pro-inflammatory signaling pathways.Targeting IRAK1 in T-cell acute lymphoblastic leukemiaThe immunomodulating neuropeptide alpha-melanocyte-stimulating hormone (alpha-MSH) suppresses LPS-stimulated TLR4 with IRAK-M in macrophages.Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice.Regulation of Transforming Growth Factor β-Activated Kinase Activation by Epigallocatechin-3-Gallate in Rheumatoid Arthritis Synovial Fibroblasts: Suppression of K(63) -Linked Autoubiquitination of Tumor Necrosis Factor Receptor-Associated Factor 6.Rewired NFκB signaling as a potentially actionable feature of activated B-cell-like diffuse large B-cell lymphoma.Lipopolysaccharide-induced activation of beta2-integrin function in macrophages requires Irak kinase activity, p38 mitogen- activated protein kinase, and the Rap1 GTPaseSurfactant lipids regulate LPS-induced interleukin-8 production in A549 lung epithelial cells by inhibiting translocation of TLR4 into lipid raft domainsIdentification of threonine 66 as a functionally critical residue of the interleukin-1 receptor-associated kinase.Functional analysis of the interleukin-1-receptor-associated kinase (IRAK-1) in interleukin-1 beta-stimulated nuclear factor kappa B (NF-kappa B) pathway activation: IRAK-1 associates with the NF-kappa B essential modulator (NEMO) upon receptor stimTransient membrane recruitment of IRAK-1 in response to LPS and IL-1beta requires TNF R1.Mass spectrometric analysis of the endogenous type I interleukin-1 (IL-1) receptor signaling complex formed after IL-1 binding identifies IL-1RAcP, MyD88, and IRAK-4 as the stable components.Pathways regulating lipopolysaccharide-induced neutrophil survival revealed by lentiviral transduction of primary human neutrophils.The catalytic activity of dsRNA-dependent protein kinase, PKR, is required for NF-kappaB activation.
P2860
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P2860
Overexpression of an enzymically inactive interleukin-1-receptor-associated kinase activates nuclear factor-kappaB
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Overexpression of an enzymical ...... ctivates nuclear factor-kappaB
@ast
Overexpression of an enzymical ...... ctivates nuclear factor-kappaB
@en
Overexpression of an enzymical ...... ctivates nuclear factor-kappaB
@en-gb
Overexpression of an enzymical ...... ctivates nuclear factor-kappaB
@nl
type
label
Overexpression of an enzymical ...... ctivates nuclear factor-kappaB
@ast
Overexpression of an enzymical ...... ctivates nuclear factor-kappaB
@en
Overexpression of an enzymical ...... ctivates nuclear factor-kappaB
@en-gb
Overexpression of an enzymical ...... ctivates nuclear factor-kappaB
@nl
prefLabel
Overexpression of an enzymical ...... ctivates nuclear factor-kappaB
@ast
Overexpression of an enzymical ...... ctivates nuclear factor-kappaB
@en
Overexpression of an enzymical ...... ctivates nuclear factor-kappaB
@en-gb
Overexpression of an enzymical ...... ctivates nuclear factor-kappaB
@nl
P2093
P2860
P356
P1433
P1476
Overexpression of an enzymical ...... ctivates nuclear factor-kappaB
@en
P2093
P2860
P304
P356
10.1042/BJ3390227
P407
P478
339 ( Pt 2)
P577
1999-04-15T00:00:00Z