Cloning and characterization of a cAMP-specific phosphodiesterase (TbPDE2B) from Trypanosoma brucei. - Wikidata - awgldk - TriplyDB

Cloning and characterization of a cAMP-specific phosphodiesterase (TbPDE2B) from Trypanosoma brucei.

Cloning and characterization of a cAMP-specific phosphodiesterase (TbPDE2B) from Trypanosoma brucei.

http://www.wikidata.org/entity/Q24536226

about

Cyclic nucleotide specific phosphodiesterases of Leishmania major.cAMP is a ligand for the tandem GAF domain of human phosphodiesterase 10 and cGMP for the tandem GAF domain of phosphodiesterase 11 PfPDE1, a novel cGMP-specific phosphodiesterase from the human malaria parasite Plasmodium falciparum Identification, characterization and subcellular localization of TcPDE1, a novel cAMP-specific phosphodiesterase from Trypanosoma cruzi.The N terminus of phosphodiesterase TbrPDEB1 of Trypanosoma brucei contains the signal for integration into the flagellar skeleton.Target repurposing for neglected diseases.Phosphodiesterase inhibitors as a new generation of antiprotozoan drugs: exploiting the benefit of enzymes that are highly conserved between host and parasite.Hydrolysis products of cAMP analogs cause transformation of Trypanosoma brucei from slender to stumpy-like forms.Pharmacological validation of Trypanosoma brucei phosphodiesterases B1 and B2 as druggable targets for African sleeping sickness.Cyclic AMP Regulates Social Behavior in African Trypanosomes.Cyclic-nucleotide signalling in protozoa.Characterization of a novel cAMP-binding, cAMP-specific cyclic nucleotide phosphodiesterase (TcrPDEB1) from Trypanosoma cruzi.Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target.Trypanosome cyclic nucleotide phosphodiesterase 2B binds cAMP through its GAF-A domain.A novel role for a Drosophila homologue of cGMP-specific phosphodiesterase in the active transport of cGMP Cytokinesis of Trypanosoma brucei bloodstream forms depends on expression of adenylyl cyclases of the ESAG4 or ESAG4-like subfamily.The Role of Phosphodiesterase-2 in Psychiatric and Neurodegenerative Disorders.Crosstalk between G-protein and Ca2+ pathways switches intracellular cAMP levels.A FYVE-containing unusual cyclic nucleotide phosphodiesterase from Trypanosoma cruzi.Immunological identification of a cAMP-dependent protein kinase regulatory subunit-like protein from the Trypanosoma equiperdum TeAp-N/D1 isolate.

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P2860

Cloning and characterization of a cAMP-specific phosphodiesterase (TbPDE2B) from Trypanosoma brucei.

http://www.wikidata.org/entity/Q24536226

description

2002 nî lūn-bûn

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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2002 թվականի ապրիլին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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name

Cloning and characterization o ...... PDE2B) from Trypanosoma brucei

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Cloning and characterization o ...... DE2B) from Trypanosoma brucei.

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Cloning and characterization o ...... DE2B) from Trypanosoma brucei.

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type

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Cloning and characterization o ...... PDE2B) from Trypanosoma brucei

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Cloning and characterization o ...... DE2B) from Trypanosoma brucei.

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Cloning and characterization o ...... DE2B) from Trypanosoma brucei.

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Cloning and characterization o ...... PDE2B) from Trypanosoma brucei

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Cloning and characterization o ...... DE2B) from Trypanosoma brucei.

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Cloning and characterization o ...... DE2B) from Trypanosoma brucei.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Cloning and characterization o ...... DE2B) from Trypanosoma brucei.

@en

P2093

Ana Rascón

http://www.w3.org/2001/XMLSchema#string

Jonathan B Schaefer

http://www.w3.org/2001/XMLSchema#string

Joseph A Beavo

http://www.w3.org/2001/XMLSchema#string

Scott H Soderling

http://www.w3.org/2001/XMLSchema#string

P2860

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Isolation and characterization of a previously undetected human cAMP phosphodiesterase by complementation of cAMP phosphodiesterase-deficient Saccharomyces cerevisiae

SMART, a simple modular architecture research tool: identification of signaling domains

Basic local alignment search tool

Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity

The Pfam protein families database.

Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae.

Characterization of TbPDE2A, a novel cyclic nucleotide-specific phosphodiesterase from the protozoan parasite Trypanosoma brucei.

cGMP binding sites on photoreceptor phosphodiesterase: role in feedback regulation of visual transduction.

Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions.

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4714-4719

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scholarly article

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10.1073/PNAS.002031599

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7

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99

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2002-04-01T00:00:00Z

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11435530

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11930017

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Trypanosoma brucei

cAMP-specific phosphodiesterase

P932

123713

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