Translesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iota
about
Insertion of dNTPs Opposite the 1, N 2 -Propanodeoxyguanosine Adduct by Sulfolobus solfataricus P2 DNA Polymerase IV † ‡Bypass of Aflatoxin B 1 Adducts by the Sulfolobus solfataricus DNA Polymerase IVReplication Bypass of the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S )-1, N 2 -Deoxyguanosine DNA Adduct by the Sulfolobus solfataricus DNA Polymerase IVInteraction of hREV1 with three human Y-family DNA polymerasesThe N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesionsInfluence of local sequence context on damaged base conformation in human DNA polymerase iota: molecular dynamics studies of nucleotide incorporation opposite a benzo[a]pyrene-derived adenine lesionCrystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymeraseInhibition of Werner syndrome helicase activity by benzo[a]pyrene diol epoxide adducts can be overcome by replication protein A.Variations on a theme: eukaryotic Y-family DNA polymerasesAdaptive upregulation of DNA repair genes following benzo(a)pyrene diol epoxide protects against cell death at the expense of mutations.Increased catalytic activity and altered fidelity of human DNA polymerase iota in the presence of manganese.Pre-steady state kinetic studies show that an abasic site is a cognate lesion for the yeast Rev1 protein.Translesion DNA polymerases and cancerPosttranslational Regulation of Human DNA Polymerase ι.Conformational searches elucidate effects of stereochemistry on structures of deoxyadenosine covalently bound to tumorigenic metabolites of benzo[C] phenanthrene.Nucleotide incorporation by human DNA polymerase gamma opposite benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyguanosine and deoxyadenosine.Accommodation of an N-(deoxyguanosin-8-yl)-2-acetylaminofluorene adduct in the active site of human DNA polymerase iota: Hoogsteen or Watson-Crick base pairing?A real-time fluorescence method for enzymatic characterization of specialized human DNA polymerases.Mouse models of DNA polymerases.Effect of DNA modifications on DNA processing by HIV-1 integrase and inhibitor binding: role of DNA backbone flexibility and an open catalytic site.Kinetic evidence for inefficient and error-prone bypass across bulky N2-guanine DNA adducts by human DNA polymerase iota.The spacious active site of a Y-family DNA polymerase facilitates promiscuous nucleotide incorporation opposite a bulky carcinogen-DNA adduct: elucidating the structure-function relationship through experimental and computational approaches.Inhibition of Werner syndrome helicase activity by benzo[c]phenanthrene diol epoxide dA adducts in DNA is both strand-and stereoisomer-dependent.Identification of amino acid residues involved in the dRP-lyase activity of human Pol ι.Translesion Synthesis: Insights into the Selection and Switching of DNA Polymerases.Translesion DNA polymerases in eukaryotes: what makes them tick?Structure and mechanism of error-free replication past the major benzo[a]pyrene adduct by human DNA polymerase κ.Accommodation of a 1S-(-)-benzo[c]phenanthrenyl-N6-dA adduct in the Y-family Dpo4 DNA polymerase active site: structural insights through molecular dynamics simulations.Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase ι.Translesion Synthesis of 2'-Deoxyguanosine Lesions by Eukaryotic DNA Polymerases.Error-Prone and Error-Free Translesion DNA Synthesis over Site-Specifically Created DNA Adducts of Aryl Hydrocarbons (3-Nitrobenzanthrone and 4-Aminobiphenyl).Increased flexibility enhances misincorporation: temperature effects on nucleotide incorporation opposite a bulky carcinogen-DNA adduct by a Y-family DNA polymerase.Kinetics of nucleotide incorporation opposite DNA bulky guanine N2 adducts by processive bacteriophage T7 DNA polymerase (exonuclease-) and HIV-1 reverse transcriptase.Bulky Lesion Bypass Requires Dpo4 Binding in Distinct Conformations.Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota.
P2860
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P2860
Translesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iota
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2002 nî lūn-bûn
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2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
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2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Translesion replication of ben ...... e by human DNA polymerase iota
@ast
Translesion replication of ben ...... e by human DNA polymerase iota
@en
Translesion replication of ben ...... e by human DNA polymerase iota
@nl
type
label
Translesion replication of ben ...... e by human DNA polymerase iota
@ast
Translesion replication of ben ...... e by human DNA polymerase iota
@en
Translesion replication of ben ...... e by human DNA polymerase iota
@nl
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Translesion replication of ben ...... e by human DNA polymerase iota
@ast
Translesion replication of ben ...... e by human DNA polymerase iota
@en
Translesion replication of ben ...... e by human DNA polymerase iota
@nl
P2093
P2860
P3181
P356
P1476
Translesion replication of ben ...... e by human DNA polymerase iota
@en
P2093
Donald M Jerina
Ekaterina G Frank
Haruo Ohmori
Heiko Kroth
Jane M Sayer
Roger Woodgate
P2860
P304
P3181
P356
10.1093/NAR/GKF643
P407
P50
P577
2002-12-01T00:00:00Z