Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts
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Translesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iotaPoleta, Polzeta and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cellsA structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignmentReplication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymeraseInteraction of hREV1 with three human Y-family DNA polymerasesDNA polymerase eta participates in the mutagenic bypass of adducts induced by benzo[a]pyrene diol epoxide in mammalian cellsCrystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymeraseInhibition of Werner syndrome helicase activity by benzo[a]pyrene diol epoxide adducts can be overcome by replication protein A.Variations on a theme: eukaryotic Y-family DNA polymerasesCrystal and molecular structure of a benzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct: absolute configuration and conformationPolkappa protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyreneError-prone translesion synthesis by human DNA polymerase eta on DNA-containing deoxyadenosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.Adaptive upregulation of DNA repair genes following benzo(a)pyrene diol epoxide protects against cell death at the expense of mutations.Structure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic featuresIntegrating S-phase checkpoint signaling with trans-lesion synthesis of bulky DNA adducts.Nucleotide incorporation by human DNA polymerase gamma opposite benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyguanosine and deoxyadenosine.DNA polymerase zeta is essential for hexavalent chromium-induced mutagenesis.Single-molecule measurements of synthesis by DNA polymerase with base-pair resolution.The spacious active site of a Y-family DNA polymerase facilitates promiscuous nucleotide incorporation opposite a bulky carcinogen-DNA adduct: elucidating the structure-function relationship through experimental and computational approaches.Involvement of vertebrate polkappa in Rad18-independent postreplication repair of UV damage.Regulation of Rad6/Rad18 Activity During DNA Damage Tolerance.Translesion DNA polymerases in eukaryotes: what makes them tick?Quantitative analysis of translesion DNA synthesis across a benzo[a]pyrene-guanine adduct in mammalian cells: the role of DNA polymerase kappa.A single site-specific trans-opened 7,8,9,10-tetrahydrobenzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct induces mutations at multiple sites in DNA.Identification of a novel REV1-interacting motif necessary for DNA polymerase kappa function.Translesion Synthesis of 2'-Deoxyguanosine Lesions by Eukaryotic DNA Polymerases.Error-Prone and Error-Free Translesion DNA Synthesis over Site-Specifically Created DNA Adducts of Aryl Hydrocarbons (3-Nitrobenzanthrone and 4-Aminobiphenyl).Increased flexibility enhances misincorporation: temperature effects on nucleotide incorporation opposite a bulky carcinogen-DNA adduct by a Y-family DNA polymerase.Roles of PCNA ubiquitination and TLS polymerases κ and η in the bypass of methyl methanesulfonate-induced DNA damage.Low fidelity DNA synthesis by a y family DNA polymerase due to misalignment in the active site.trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases.Kinetics of nucleotide incorporation opposite DNA bulky guanine N2 adducts by processive bacteriophage T7 DNA polymerase (exonuclease-) and HIV-1 reverse transcriptase.Structure of a high fidelity DNA polymerase bound to a benzo[a]pyrene adduct that blocks replication.Mutagenic Replication of N2-Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase I and Sulfolobus solfataricus DNA Polymerase IV.
P2860
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P2860
Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts
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2002 nî lūn-bûn
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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Preferential misincorporation ...... epoxide deoxyguanosine adducts
@ast
Preferential misincorporation ...... epoxide deoxyguanosine adducts
@en
Preferential misincorporation ...... epoxide deoxyguanosine adducts
@nl
type
label
Preferential misincorporation ...... epoxide deoxyguanosine adducts
@ast
Preferential misincorporation ...... epoxide deoxyguanosine adducts
@en
Preferential misincorporation ...... epoxide deoxyguanosine adducts
@nl
prefLabel
Preferential misincorporation ...... epoxide deoxyguanosine adducts
@ast
Preferential misincorporation ...... epoxide deoxyguanosine adducts
@en
Preferential misincorporation ...... epoxide deoxyguanosine adducts
@nl
P2093
P2860
P3181
P356
P1476
Preferential misincorporation ...... epoxide deoxyguanosine adducts
@en
P2093
Albert M Cheh
Chikahide Masutani
Dominic Chiapperino
Donald M Jerina
Fumio Hanaoka
Heiko Kroth
Irene H Kramarczuk
Jane M Sayer
P2860
P304
P3181
P356
10.1074/JBC.M112139200
P407
P577
2002-04-05T00:00:00Z