SynGAP regulates synaptic strength and mitogen-activated protein kinases in cultured neurons - Wikidata - awgldk - TriplyDB

SynGAP regulates synaptic strength and mitogen-activated protein kinases in cultured neurons

SynGAP regulates synaptic strength and mitogen-activated protein kinases in cultured neurons

http://www.wikidata.org/entity/Q24545222

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Calmodulin-kinases: modulators of neuronal development and plasticity Pathogenic SYNGAP1 mutations impair cognitive development by disrupting maturation of dendritic spine synapses.Mutations in SYNGAP1 in autosomal nonsyndromic mental retardation Stress-induced p38 mitogen-activated protein kinase activation mediates kappa-opioid-dependent dysphoria.Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking SYNGAP1: Mind the Gap Two knockdown models of the autism genes SYNGAP1 and SHANK3 in zebrafish produce similar behavioral phenotypes associated with embryonic disruptions of brain morphogenesis.Neuronal death induced by misfolded prion protein is due to NAD+ depletion and can be relieved in vitro and in vivo by NAD+ replenishment.Rapid dispersion of SynGAP from synaptic spines triggers AMPA receptor insertion and spine enlargement during LTP.The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction A Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.SynGAP isoforms exert opposing effects on synaptic strength Myosin IIb regulates actin dynamics during synaptic plasticity and memory formation SynGAP moves out of the core of the postsynaptic density upon depolarization Synaptic activity prompts gamma-secretase-mediated cleavage of EphA4 and dendritic spine formation High-throughput sequencing of mGluR signaling pathway genes reveals enrichment of rare variants in autism Evolutionary expansion of the Ras switch regulatory module in eukaryotes Estradiol induces hypothalamic dendritic spines by enhancing glutamate release: a mechanism for organizational sex differences Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability Prioritizing the development of mouse models for childhood brain disorders Ras and Rap signaling in synaptic plasticity and mental disorders.Reduced expression of the NMDA receptor-interacting protein SynGAP causes behavioral abnormalities that model symptoms of Schizophrenia Rapid enhancement of two-step wiring plasticity by estrogen and NMDA receptor activity Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking.Reduced cognition in Syngap1 mutants is caused by isolated damage within developing forebrain excitatory neurons Decrease of SYNGAP1 in GABAergic cells impairs inhibitory synapse connectivity, synaptic inhibition and cognitive function.Integrated analysis of clinical signs and literature data for the diagnosis and therapy of a previously undescribed 6p21.3 deletion syndrome Alterations in STriatal-Enriched protein tyrosine Phosphatase expression, activation, and downstream signaling in early and late stages of the YAC128 Huntington's disease mouse model.Glutamatergic gene expression is specifically reduced in thalamocortical projecting relay neurons in schizophrenia.Tyrosine phosphoproteomics identifies both codrivers and cotargeting strategies for T790M-related EGFR-TKI resistance in non-small cell lung cancer.The genetic basis of non-syndromic intellectual disability: a review Small G protein signaling in neuronal plasticity and memory formation: the specific role of ras family proteins Profile of Richard L. Huganir.Beta-adrenergic receptor activation rescues theta frequency stimulation-induced LTP deficits in mice expressing C-terminally truncated NMDA receptor GluN2A subunits.Regulation of synapse structure and function by distinct myosin II motors.Camkii-mediated phosphorylation regulates distributions of Syngap-α1 and -α2 at the postsynaptic density.Spine growth in the anterior cingulate cortex is necessary for the consolidation of contextual fear memory IQGAP1 regulates NR2A signaling, spine density, and cognitive processes.Syngap1 haploinsufficiency damages a postnatal critical period of pyramidal cell structural maturation linked to cortical circuit assembly SynGAP regulates protein synthesis and homeostatic synaptic plasticity in developing cortical networks.

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P2860

SynGAP regulates synaptic strength and mitogen-activated protein kinases in cultured neurons

http://www.wikidata.org/entity/Q24545222

description

2006 nî lūn-bûn

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2006 թուականի Մարտին հրատարակուած գիտական յօդուած

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2006 թվականի մարտին հրատարակված գիտական հոդված

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2006年論文

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SynGAP regulates synaptic stre ...... in kinases in cultured neurons

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SynGAP regulates synaptic stre ...... in kinases in cultured neurons

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SynGAP regulates synaptic stre ...... in kinases in cultured neurons

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type

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SynGAP regulates synaptic stre ...... in kinases in cultured neurons

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SynGAP regulates synaptic stre ...... in kinases in cultured neurons

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SynGAP regulates synaptic stre ...... in kinases in cultured neurons

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prefLabel

SynGAP regulates synaptic stre ...... in kinases in cultured neurons

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SynGAP regulates synaptic stre ...... in kinases in cultured neurons

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SynGAP regulates synaptic stre ...... in kinases in cultured neurons

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Proceedings of the National Academy of Sciences of the United States of America

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SynGAP regulates synaptic stre ...... in kinases in cultured neurons

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Gavin Rumbaugh

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J Paige Adams

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Jee H Kim

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Richard L Huganir

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P2860

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

AMPA receptor trafficking and long-term potentiation

Synapse-associated protein-97 isoform-specific regulation of surface AMPA receptors and synaptic function in cultured neurons

Cerebral ischemia immediately increases serine phosphorylation of the synaptic RAS-GTPase activating protein SynGAP by calcium/calmodulin-dependent protein kinase II alpha in hippocampus of rats

Transient cerebral ischemia increases tyrosine phosphorylation of the synaptic RAS-GTPase activating protein, SynGAP

The role of synaptic GTPase-activating protein in neuronal development and synaptic plasticity

Regulation of the neuron-specific Ras GTPase-activating protein, synGAP, by Ca2+/calmodulin-dependent protein kinase II

SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family

A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II

SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation

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