COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system - Wikidata - awgldk - TriplyDB

COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system

COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system

http://www.wikidata.org/entity/Q24545648

about

CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis CSN complex controls the stability of selected synaptic proteins via a torsinA-dependent process Jab1 antagonizes TGF-beta signaling by inducing Smad4 degradation Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p Novel curcumin- and emodin-related compounds identified by in silico 2D/3D conformer screening induce apoptosis in tumor cells The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and Repair The DenA/DEN1 Interacting Phosphatase DipA Controls Septa Positioning and Phosphorylation-Dependent Stability of Cytoplasmatic DenA/DEN1 during Fungal Development Crystal structure and versatile functional roles of the COP9 signalosome subunit 1 Structure characterization of the 26S proteasome.COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae.Subunit interaction maps for the regulatory particle of the 26S proteasome and the COP9 signalosome.Rpn6p, a proteasome subunit from Saccharomyces cerevisiae, is essential for the assembly and activity of the 26 S proteasome.Honokiol, a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivo The COP9 signalosome: an assembly and maintenance platform for cullin ubiquitin ligases?Amplification and overexpression of COPS3 in osteosarcomas potentially target TP53 for proteasome-mediated degradation Cell cycle regulation and p53 activation by protein phosphatase 2C alpha The role of transcriptional corepressor Nif3l1 in early stage of neural differentiation via cooperation with Trip15/CSN2 Inositol 1,3,4-trisphosphate 5/6-kinase associates with the COP9 signalosome by binding to CSN1 Human immunodeficiency virus type 1 (HIV-1) Vpr-regulated cell death: insights into mechanism Hepatopoietin interacts directly with COP9 signalosome and regulates AP-1 activity Multiple functions of Jab1 are required for early embryonic development and growth potential in mice COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast The COP9 signalosome converts temporal hormone signaling to spatial restriction on neural competence The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting Disruption of the COP9 signalosome Csn2 subunit in mice causes deficient cell proliferation, accumulation of p53 and cyclin E, and early embryonic death The Evolution of COP9 Signalosome in Unicellular and Multicellular Organisms Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex Domain-mediated protein interaction prediction: From genome to network.Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif.Fank1 interacts with Jab1 and regulates cell apoptosis via the AP-1 pathway.Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer Downregulation of COP9 signalosome subunits differentially affects the CSN complex and target protein stability Regulation of Cop9 signalosome activity by the EF-hand Ca2+-binding protein tescalcin A novel p53 phosphorylation site within the MDM2 ubiquitination signal: I. phosphorylation at SER269 in vivo is linked to inactivation of p53 function.COP9 subunits 4 and 5 target soluble guanylyl cyclase α1 and p53 in prostate cancer cells.Knockdown of COPS3 Inhibits Lung Cancer Tumor Growth in Nude Mice by Blocking Cell Cycle Progression.Mutant TP53 posttranslational modifications: challenges and opportunities.

P2860

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P2860

COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system

http://www.wikidata.org/entity/Q24545648

description

2001 nî lūn-bûn

@nan

2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

COP9 signalosome-specific phos ...... dation by the ubiquitin system

@ast

COP9 signalosome-specific phos ...... dation by the ubiquitin system

@en

COP9 signalosome-specific phos ...... dation by the ubiquitin system

@nl

type

label

COP9 signalosome-specific phos ...... dation by the ubiquitin system

@ast

COP9 signalosome-specific phos ...... dation by the ubiquitin system

@en

COP9 signalosome-specific phos ...... dation by the ubiquitin system

@nl

prefLabel

COP9 signalosome-specific phos ...... dation by the ubiquitin system

@ast

COP9 signalosome-specific phos ...... dation by the ubiquitin system

@en

COP9 signalosome-specific phos ...... dation by the ubiquitin system

@nl

P1433

Q24545648-A9B1DDB3-BFA6-47B7-B0A4-EDE556F4BA56

P1476

Q24545648-38A8005C-DD30-4237-8B20-DE8130CD14DD

P2093

Q24545648-5A38FF8F-6131-4354-9F73-4F99D6969301

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Q24545648-9F3701BF-0ADC-477F-ACB5-0F0434DE1A8A

Q24545648-C684A88C-7E11-4C65-B94B-4006EDF06B69

Q24545648-DB0488E3-05B9-403C-8506-E605F8AD93CD

Q24545648-E6F6850D-8C98-4A1A-9D8A-B9E2D85ACF02

P2860

Q24545648-1212A29B-31B1-4886-90B3-1D7C1426C6C2

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Q24545648-183EEF75-B1D1-4553-BE51-06EDE79327D8

Q24545648-1DCDB89E-547B-44E2-A3E1-A33097622932

Q24545648-2BD62192-8B65-4D63-BB35-6A5A1A06CDC4

Q24545648-30D3E885-5E85-4CC9-A596-2D9109C638AA

Q24545648-3295F38F-2E41-4227-A24D-0F17E690077F

Q24545648-43FD4ACB-5646-4AA3-A639-C805DE91C937

Q24545648-48A9A50E-B9B6-40EA-9BC4-9CEC6BA5B233

Q24545648-4B5EC426-58CC-487D-8160-CD09E6206066

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Q24545648-3236BAD1-ACF0-499B-8958-7D2C49895E21

P3181

Q24545648-6BE0D398-D819-49D9-AA86-92AA5AFBD7B9

P356

Q24545648-CDB3B69D-0A49-46FA-8ACA-1EB0FFB76544

P407

Q24545648-47227E65-CFC9-4C87-AA0F-D2FBBB273E9B

P433

Q24545648-17999AD2-F3F2-45EA-A112-E2BB184A5131

P478

Q24545648-B0883595-5AC4-474C-8A1D-3488224F8453

P50

Q24545648-251A1F20-03EF-4BF0-8970-08F07BC4D508

P577

Q24545648-B28A8CDB-A6E3-45F9-A45A-3F3DA0E1D515

P5875

Q24545648-55FFECA0-4BCC-4C4D-98FD-500B7FE8983C

P698

Q24545648-B04CD02F-6FAD-4E9A-9EB6-7A608A65C232

P921

Q24545648-5AF8F71E-E198-4DA9-A7B5-0372C8EF08CB

P932

Q24545648-01CCD486-266F-4ACC-8C02-931CD2806414

P3181

P356

P1433

The EMBO Journal

P1476

COP9 signalosome-specific phos ...... dation by the ubiquitin system

@en

P2093

B Kapelari

http://www.w3.org/2001/XMLSchema#string

C Pollmann

http://www.w3.org/2001/XMLSchema#string

D Bech-Otschir

http://www.w3.org/2001/XMLSchema#string

P Henklein

http://www.w3.org/2001/XMLSchema#string

R Kraft

http://www.w3.org/2001/XMLSchema#string

X Huang

http://www.w3.org/2001/XMLSchema#string

P2860

The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators

A new group of conserved coactivators that increase the specificity of AP-1 transcription factors

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits

Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

The ubiquitin system

A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3.

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

JAB1 interacts with both the progesterone receptor and SRC-1

P304

1630-1639

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1259495

http://www.w3.org/2001/XMLSchema#string

P356

10.1093/EMBOJ/20.7.1630

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

20

http://www.w3.org/2001/XMLSchema#string

P50

Wolfgang Dubiel

P577

2001-04-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

12049006

http://www.w3.org/2001/XMLSchema#string

P698

11285227

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

145508

http://www.w3.org/2001/XMLSchema#string