A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha
about
Modulation of protein translation by Nck-1.C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase geneTranslational Upregulation of an Individual p21Cip1 Transcript Variant by GCN2 Regulates Cell Proliferation and Survival under Nutrient StressSignaling by target of rapamycin proteins in cell growth controlAssociation of GCN1-GCN20 regulatory complex with the N-terminus of eIF2alpha kinase GCN2 is required for GCN2 activationThe roles of nitric oxide synthase and eIF2alpha kinases in regulation of cell cycle upon UVB-irradiationNrf2 is a direct PERK substrate and effector of PERK-dependent cell survivalNutrient-sensing mechanisms across evolutionCrystal Structures of GCN2 Protein Kinase C-terminal Domains Suggest Regulatory Differences in Yeast and MammalsSystems vaccinology: probing humanity's diverse immune systems with vaccines.The yeast eukaryotic translation initiation factor 2B translation initiation complex interacts with the fatty acid synthesis enzyme YBR159W and endoplasmic reticulum membranesSeparate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells.Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) is a pro-survival, endoplasmic reticulum (ER) stress response gene involved in tumor cell adaptation to nutrient availabilityGlucose exerts a permissive effect on the regulation of the initiation factor 4E binding protein 4E-BP1Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiencyThe PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreasActivating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress responseFeedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alphaAntiviral effect of the mammalian translation initiation factor 2alpha kinase GCN2 against RNA virusesTranslational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2Heme-regulated eIF2alpha kinase modifies the phenotypic severity of murine models of erythropoietic protoporphyria and beta-thalassemiaVaccine activation of the nutrient sensor GCN2 in dendritic cells enhances antigen presentationTranslational control by eIF2α kinases in long-lasting synaptic plasticity and long-term memory.Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis.Human Herpesvirus 6A Exhibits Restrictive Propagation with Limited Activation of the Protein Kinase R-eIF2α Stress Pathway.Amino acids regulate transgene expression in MDCK cells.The role of the innate immune response regulatory gene ABCF1 in mammalian embryogenesis and developmentArginase II restricts host defense to Helicobacter pylori by attenuating inducible nitric oxide synthase translation in macrophagesCoronavirus infection, ER stress, apoptosis and innate immunityFrom Krebs to clinic: glutamine metabolism to cancer therapy.Expression profiling after activation of amino acid deprivation response in HepG2 human hepatoma cellsAsparagine synthetase: a new potential biomarker in ovarian cancer.Gcn4p, a master regulator of gene expression, is controlled at multiple levels by diverse signals of starvation and stress.The general amino acid control pathway regulates mTOR and autophagy during serum/glutamine starvationGlucose limitation induces GCN4 translation by activation of Gcn2 protein kinase.Activation of the amino acid response modulates lineage specification during differentiation of murine embryonic stem cells.Translation initiation control by heme-regulated eukaryotic initiation factor 2alpha kinase in erythroid cells under cytoplasmic stresses.The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice.Asparagine synthetase chemotherapy.Differential activation of eIF2 kinases in response to cellular stresses in Schizosaccharomyces pombe.
P2860
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P2860
A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha
description
2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
@wuu
name
A mammalian homologue of GCN2 ...... yotic initiation factor-2alpha
@ast
A mammalian homologue of GCN2 ...... yotic initiation factor-2alpha
@en
A mammalian homologue of GCN2 ...... yotic initiation factor-2alpha
@nl
type
label
A mammalian homologue of GCN2 ...... yotic initiation factor-2alpha
@ast
A mammalian homologue of GCN2 ...... yotic initiation factor-2alpha
@en
A mammalian homologue of GCN2 ...... yotic initiation factor-2alpha
@nl
prefLabel
A mammalian homologue of GCN2 ...... yotic initiation factor-2alpha
@ast
A mammalian homologue of GCN2 ...... yotic initiation factor-2alpha
@en
A mammalian homologue of GCN2 ...... yotic initiation factor-2alpha
@nl
P2093
P2860
P3181
P1433
P1476
A mammalian homologue of GCN2 ...... yotic initiation factor-2alpha
@en
P2093
P2860
P304
P3181
P407
P577
2000-02-01T00:00:00Z