Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum.
about
STIM1 couples to ORAI1 via an intramolecular transition into an extended conformationA novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cellsSTIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1STIM proteins: dynamic calcium signal transducersSTIM1 heteromultimerizes TRPC channels to determine their function as store-operated channelsSTIM and Orai1 Variants in Store-Operated Calcium EntryThe STIM1/Orai signaling machineryMolecular regulation of CRAC channels and their role in lymphocyte functionStore-operated Orai channels: structure and functionStore-operated Ca2+ entry (SOCE) regulates melanoma proliferation and cell migrationAuto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entryStructural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1)Mapping the interacting domains of STIM1 and Orai1 in Ca2+ release-activated Ca2+ channel activationSTIM1 gates the store-operated calcium channel ORAI1 in vitroStromal interaction molecule (STIM) 1 and STIM2 calcium sensing regions exhibit distinct unfolding and oligomerization kineticsConformational Changes in the Orai1 C-Terminus Evoked by STIM1 BindingAnimal Ca2+ release-activated Ca2+ (CRAC) channels appear to be homologous to and derived from the ubiquitous cation diffusion facilitators.Some assembly required: constructing the elementary units of store-operated Ca2+ entry.Novel role for STIM1 as a trigger for calcium influx factor production.Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps.STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER.STIMulating store-operated Ca(2+) entry.STIM1 translocation to the plasma membrane enhances intestinal epithelial restitution by inducing TRPC1-mediated Ca2+ signaling after wounding.Single-molecule analysis of diffusion and trapping of STIM1 and Orai1 at endoplasmic reticulum-plasma membrane junctions.Requirement for store-operated calcium entry in sodium butyrate-induced apoptosis in human colon cancer cells.The Drosophila STIM1 orthologue, dSTIM, has roles in cell fate specification and tissue patterning.Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domainHigh glucose and diabetes enhanced store-operated Ca(2+) entry and increased expression of its signaling proteins in mesangial cells.Identification of a polycystin-1 cleavage product, P100, that regulates store operated Ca entry through interactions with STIM1.Molecular basis of calcium signaling in lymphocytes: STIM and ORAIImaging intraorganellar Ca2+ at subcellular resolution using CEPIACalcium signaling in immune cells.Essential role for the CRAC activation domain in store-dependent oligomerization of STIM1.Regulation of store-operated Ca2+ entry during the cell cycleRemodelling of the endoplasmic reticulum during store-operated calcium entry.S-glutathionylation activates STIM1 and alters mitochondrial homeostasis.STIM proteins and the endoplasmic reticulum-plasma membrane junctions.Visualisation and identification of the interaction between STIM1s in resting cells.Molecular underpinning of B-cell anergy.Calcium signaling in lymphocytes
P2860
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P2860
Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum.
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Coupling of STIM1 to store-ope ...... t in the endoplasmic reticulum
@nl
Coupling of STIM1 to store-ope ...... in the endoplasmic reticulum.
@ast
Coupling of STIM1 to store-ope ...... in the endoplasmic reticulum.
@en
type
label
Coupling of STIM1 to store-ope ...... t in the endoplasmic reticulum
@nl
Coupling of STIM1 to store-ope ...... in the endoplasmic reticulum.
@ast
Coupling of STIM1 to store-ope ...... in the endoplasmic reticulum.
@en
prefLabel
Coupling of STIM1 to store-ope ...... t in the endoplasmic reticulum
@nl
Coupling of STIM1 to store-ope ...... in the endoplasmic reticulum.
@ast
Coupling of STIM1 to store-ope ...... in the endoplasmic reticulum.
@en
P2093
P2860
P3181
P356
P1476
Coupling of STIM1 to store-ope ...... in the endoplasmic reticulum.
@en
P2093
Akiko Mizushima
Hiroshi Watarai
Kenji Hayashi
Masaki Hikida
Masamitsu Iino
Minoru Wakamori
Takuro Numaga
Tomohiro Kurosaki
Yasuo Mori
Yoko Fujii
P2860
P304
16704-16709
P3181
P356
10.1073/PNAS.0608358103
P407
P577
2006-10-30T00:00:00Z