Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase - Wikidata - awgldk - TriplyDB

Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase

Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase

http://www.wikidata.org/entity/Q24554376

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Psychological therapies for sickle cell disease and pain HIF prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques The Cell Killing Mechanisms of Hydroxyurea Information exploration system for sickle cell disease and repurposing of hydroxyfasudil Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice Genetic and biochemical markers of hydroxyurea therapeutic response in sickle cell anemia.Identification of differentially expressed genes induced by hydroxyurea in reticulocytes from sickle cell anaemia patients.A pilot study of electronic directly observed therapy to improve hydroxyurea adherence in pediatric patients with sickle-cell disease.Antisickling property of fetal hemoglobin enhances nitric oxide bioavailability and ameliorates organ oxidative stress in transgenic-knockout sickle mice.Generation of a genomic reporter assay system for analysis of γ- and β-globin gene regulation.Effective control of sickle cell disease with hydroxyurea therapy.How I use hydroxyurea to treat young patients with sickle cell anemia.Hydroxyurea-inducible SAR1 gene acts through the Giα/JNK/Jun pathway to regulate γ-globin expression Hydroxyurea-induced expression of glutathione peroxidase 1 in red blood cells of individuals with sickle cell anemia Concepts in hypoxia reborn Hydroxycarbamide: a user's guide for chronic myeloproliferative disorders.Hydroxyurea treatment in β-thalassemia patients: to respond or not to respond?Globin gene expression in correlation with G protein-related genes during erythroid differentiation.Sickle red cell-endothelium interactions.Induction of human fetal hemoglobin via the NRF2 antioxidant response signaling pathway Population pharmacokinetics and pharmacodynamics of hydroxyurea in sickle cell anemia patients, a basis for optimizing the dosing regimen.Pharmacotherapy in sickle cell disease--state of the art and future prospects Hydroxyurea for sickle cell anemia: what have we learned and what questions still remain?Epigenetic and molecular profiles of erythroid cells after hydroxyurea treatment in sickle cell anemia.Pathological basis of symptoms and crises in sickle cell disorder: implications for counseling and psychotherapy The proinflammatory cytokine GM-CSF downregulates fetal hemoglobin expression by attenuating the cAMP-dependent pathway in sickle cell disease.Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells Sickle cell disease: old discoveries, new concepts, and future promise.Nitric Oxide-cGMP Signaling Stimulates Erythropoiesis through Multiple Lineage-Specific Transcription Factors: Clinical Implications and a Novel Target for Erythropoiesis.Prospects for primary stroke prevention in children with sickle cell anaemia Predicting clinical severity in sickle cell anaemia.JAK-STAT and AKT pathway-coupled genes in erythroid progenitor cells through ontogeny Hydroxyurea with AKT2 inhibition decreases vaso-occlusive events in sickle cell disease mice Sickle cell disease and nitric oxide: a paradigm shift?Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin Hydroxyurea nitrosylates and activates soluble guanylyl cyclase in human erythroid cells.Transcellular movement of hydroxyurea is mediated by specific solute carrier transporters.Investigational agents for sickle cell disease.Fetal haemoglobin response to hydroxycarbamide treatment and sar1a promoter polymorphisms in sickle cell anaemia.Neutrophils, platelets, and inflammatory pathways at the nexus of sickle cell disease pathophysiology.

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Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase

http://www.wikidata.org/entity/Q24554376

description

2003 nî lūn-bûn

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2003 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2003 թվականի հունվարին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Hydroxyurea induces fetal hemo ...... on of soluble guanylyl cyclase

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Hydroxyurea induces fetal hemo ...... on of soluble guanylyl cyclase

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Hydroxyurea induces fetal hemo ...... on of soluble guanylyl cyclase

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type

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Hydroxyurea induces fetal hemo ...... on of soluble guanylyl cyclase

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Hydroxyurea induces fetal hemo ...... on of soluble guanylyl cyclase

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Hydroxyurea induces fetal hemo ...... on of soluble guanylyl cyclase

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Hydroxyurea induces fetal hemo ...... on of soluble guanylyl cyclase

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Hydroxyurea induces fetal hemo ...... on of soluble guanylyl cyclase

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Hydroxyurea induces fetal hemo ...... on of soluble guanylyl cyclase

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P1433

Journal of Clinical Investigation

P1476

Hydroxyurea induces fetal hemo ...... on of soluble guanylyl cyclase

@en

P2093

Bojana B Beleslin-Cokic

http://www.w3.org/2001/XMLSchema#string

Jeffery L Miller

http://www.w3.org/2001/XMLSchema#string

Joyce M Njoroge

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Mark T Gladwin

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Reginald D Smith

http://www.w3.org/2001/XMLSchema#string

P2860

Guanylate cyclase and the .NO/cGMP signaling pathway

Nitric oxide activation of p38 mitogen-activated protein kinase in 293T fibroblasts requires cGMP-dependent protein kinase

Pharmacologic induction of fetal hemoglobin: raising the therapeutic bar in sickle cell disease.

Synergistic enhancement of globin gene expression by activator protein-1-like proteins.

Mechanism for fetal globin gene expression: role of the soluble guanylate cyclase-cGMP-dependent protein kinase pathway.

Augmentation by erythropoietin of the fetal-hemoglobin response to hydroxyurea in sickle cell disease.

Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia.

Hydroxyurea inhibition of DNA synthesis in ascites tumor

Mechanism of action of hydroxyurea.

Influence of cell cycle phase-specific agents on simian fetal hemoglobin synthesis.

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231-239

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scholarly article

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147160

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10.1172/JCI16672

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10.1172/JCI200316672

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P407

P433

2

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111

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Alan Neil Schechter

Vladan P Čokić

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2003-01-01T00:00:00Z

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12531879

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151872

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