Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin - Wikidata - awgldk - TriplyDB

Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin

Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin

http://www.wikidata.org/entity/Q36384665

about

Epigenetic regulation of fetal globin gene expression in adult erythroid cells Trials with 'epigenetic' drugs: an update In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia.Induction of fetal hemoglobin through enhanced translation efficiency of γ-globin mRNA Compound loss of function of nuclear receptors Tr2 and Tr4 leads to induction of murine embryonic β-type globin genes MBD2 contributes to developmental silencing of the human ε-globin gene.Induction of human fetal hemoglobin via the NRF2 antioxidant response signaling pathway Epigenetic therapy for breast cancer.Epigenetic and molecular profiles of erythroid cells after hydroxyurea treatment in sickle cell anemia.Induction of human fetal hemoglobin expression by adenosine-2',3'-dialdehyde.Hemoglobin research and the origins of molecular medicine.Eukaryotic initiation factor 2α phosphorylation mediates fetal hemoglobin induction through a post-transcriptional mechanism Transcriptional mechanisms underlying hemoglobin synthesis.β-Thalassemia due to intronic LINE-1 insertion in the β-globin gene (HBB): molecular mechanisms underlying reduced transcript levels of the β-globin(L1) allele Epigenetics of beta-globin gene regulation Short-chain fatty acid-mediated effects on erythropoiesis in primary definitive erythroid cells.5-azacytidine affects TET2 and histone transcription and reshapes morphology of human skin fibroblasts.Natural Remedies for the Treatment of Beta-Thalassemia and Sickle Cell Anemia-Current Status and Perspectives in Fetal Hemoglobin Reactivation.Epigenetic dysfunctional diseases and therapy for infection and inflammation.siDNMT1 increases γ-globin expression in chemical inducer of dimerization (CID)-dependent mouse βYAC bone marrow cells and in baboon erythroid progenitor cell cultures.Decitabine increases fetal hemoglobin in Papio anubis by increasing γ-globin gene transcription.Stimulus duration and response time independently influence the kinetics of lytic cycle reactivation of Epstein-Barr virus.S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis)Developmentally regulated extended domains of DNA hypomethylation encompass highly transcribed genes of the human beta-globin locus.Stressing HbF synthesis: role of translation?Evolution of hemoglobin loci and their regulatory elements.Clinical evaluation of combined azacitidine and entinostat on the induction of fetal hemoglobin in patients with acute myeloid leukemias and myelodysplastic syndromes.KLF10gene expression is associated with high fetal hemoglobin levels and with response to hydroxyurea treatment in β-hemoglobinopathy patients

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P2860

Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin

http://www.wikidata.org/entity/Q36384665

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

@zh-hant

name

Neither DNA hypomethylation no ...... induce human fetal hemoglobin

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Neither DNA hypomethylation no ...... induce human fetal hemoglobin

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type

label

Neither DNA hypomethylation no ...... induce human fetal hemoglobin

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Neither DNA hypomethylation no ...... induce human fetal hemoglobin

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prefLabel

Neither DNA hypomethylation no ...... induce human fetal hemoglobin

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Neither DNA hypomethylation no ...... induce human fetal hemoglobin

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Neither DNA hypomethylation no ...... induce human fetal hemoglobin

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Christine A Richardson

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Christopher H Lowrey

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Courtney D Kozul

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Michael R Greene

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Rodwell Mabaera

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Sarah J Conine

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P2860

EUKARYOTIC CYTOSINE METHYLTRANSFERASES

Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase

A standard curve based method for relative real time PCR data processing

Cell cycle and cell death regulation of neural progenitor cells in the 5-azacytidine (5AzC)-treated developing fetal brain

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

Control of globin gene expression during development and erythroid differentiation

Butyrate increases the efficiency of translation of gamma-globin mRNA.

Mechanism for fetal globin gene expression: role of the soluble guanylate cyclase-cGMP-dependent protein kinase pathway.

Induction of fetal globin in beta-thalassemia: Cellular obstacles and molecular progress.

5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy.

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411-420

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