Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells
about
Nedd4-2 and the regulation of epithelial sodium transportNedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and functionRegulation of trafficking of activated TrkA is critical for NGF-mediated functionsNedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functionsUbiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global ProfilingThe Rac1 hypervariable region in targeting and signaling: a tail of many storiesThe predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradationPTEN is a protein tyrosine phosphatase for IRS1The ubiquitin ligase Nedd4-1 is required for heart development and is a suppressor of thrombospondin-1E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arraysUsp12 stabilizes the T-cell receptor complex at the cell surface during signalingEndocytic regulation of alkali metal transport proteins in mammals, yeast and plants.E3 ubiquitin ligase Cbl-b in innate and adaptive immunity.A splice isoform of DNedd4, DNedd4-long, negatively regulates neuromuscular synaptogenesis and viability in Drosophila.Regulation of T cell receptor complex-mediated signaling by ubiquitin and ubiquitin-like modificationsNEDD4-1 regulates migration and invasion of glioma cells through CNrasGEF ubiquitination in vitro.E3 ubiquitin ligase Cbl-b regulates Pten via Nedd4 in T cells independently of its ubiquitin ligase activityProtein Tyrosine Phosphatase SHP-1 Modulates T Cell Responses by Controlling Cbl-b DegradationNdfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cellsE3-ubiquitin ligase Nedd4 determines the fate of AID-associated RNA polymerase II in B cells.Cbl- and Nedd4-family ubiquitin ligases: balancing tolerance and immunityThe ubiquitin ligase adaptor Ndfip1 regulates T cell-mediated gastrointestinal inflammation and inflammatory bowel disease susceptibility.E3 ubiquitin ligases in T-cell tolerance.Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models.Ubiquitination of E3 ligases: self-regulation of the ubiquitin system via proteolytic and non-proteolytic mechanisms.Ubiquitination in host immune response to human papillomavirus infection.Mechanisms that regulate peripheral immune responses to control organ-specific autoimmunity.Modulation of Immune Cell Functions by the E3 Ligase Cbl-b.Ubiquitin Ligases and Deubiquitinating Enzymes in CD4+ T Cell Effector Fate Choice and Function.Phospho-Smad1 modulation by nedd4 E3 ligase in BMP/TGF-β signaling.E3 ubiquitin ligase Nedd4 inhibits AP-1 activity and TNF-α production through targeting p38α for polyubiquitination and subsequent degradation.K33-linked polyubiquitination of T cell receptor-zeta regulates proteolysis-independent T cell signalingNdfip1 enforces a requirement for CD28 costimulation by limiting IL-2 productionNEDD4 ubiquitinates TRAF3 to promote CD40-mediated AKT activation.Glycogen Synthase Kinase-3 Modulates Cbl-b and Constrains T Cell Activation.E3 ubiquitin ligases in cancer and implications for therapies.Immune Regulation by Ubiquitin Tagging as Checkpoint Code.A peripheral blood transcriptomic signature predicts autoantibody development in infants at risk of type 1 diabetes.Intestinal knockout of Nedd4 enhances growth of Apcmin tumors.
P2860
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P2860
Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Nedd4 augments the adaptive im ...... of Cbl-b in activated T cells
@ast
Nedd4 augments the adaptive im ...... of Cbl-b in activated T cells
@en
Nedd4 augments the adaptive im ...... of Cbl-b in activated T cells
@nl
type
label
Nedd4 augments the adaptive im ...... of Cbl-b in activated T cells
@ast
Nedd4 augments the adaptive im ...... of Cbl-b in activated T cells
@en
Nedd4 augments the adaptive im ...... of Cbl-b in activated T cells
@nl
prefLabel
Nedd4 augments the adaptive im ...... of Cbl-b in activated T cells
@ast
Nedd4 augments the adaptive im ...... of Cbl-b in activated T cells
@en
Nedd4 augments the adaptive im ...... of Cbl-b in activated T cells
@nl
P2093
P2860
P3181
P356
P1433
P1476
Nedd4 augments the adaptive im ...... of Cbl-b in activated T cells
@en
P2093
Baoli Yang
Denise L Gay
Eileen M Sweezer
Megan K L MacLeod
Paula M Oliver
Tamara Hala
P2860
P304
P3181
P356
10.1038/NI.1670
P407
P577
2008-12-01T00:00:00Z