The RNA polymerase "switch region" is a target for inhibitors - Wikidata - awgldk - TriplyDB

The RNA polymerase "switch region" is a target for inhibitors

The RNA polymerase "switch region" is a target for inhibitors

http://www.wikidata.org/entity/Q24643039

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GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides Structures of RNA polymerase-antibiotic complexes Tagetitoxin inhibits RNA polymerase through trapping of the trigger loop Response to Klyuyev and Vassylyev: on the mechanism of tagetitoxin inhibition of transcription Opening and closing of the bacterial RNA polymerase clamp New target for inhibition of bacterial RNA polymerase: 'switch region'Elucidating the inhibition mechanism of HIV-1 non-nucleoside reverse transcriptase inhibitors through multicopy molecular dynamics simulations Antibiotics from predatory bacteria Three-dimensional EM structure of an intact activator-dependent transcription initiation complex Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein X-ray Crystal Structure of Escherichia coli RNA Polymerase 70 Holoenzyme HIV-1 reverse transcriptase complex with DNA and nevirapine reveals non-nucleoside inhibition mechanism Interaction of the Mediator Head Module with RNA Polymerase II Structural basis for promoter specificity switching of RNA polymerase by a phage factor Transcription inhibition by the depsipeptide antibiotic salinamide A Bacterial RNA Polymerase-DNA Interaction-The Driving Force of Gene Expression and the Target for Drug Action Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase Solving the Puzzle of One-Carbon Loss in Ripostatin Biosynthesis.Molecular evolution of multisubunit RNA polymerases: structural analysis A prehydrolysis state of an AAA+ ATPase supports transcription activation of an enhancer-dependent RNA polymerase Multiple roles of the RNA polymerase {beta}' SW2 region in transcription initiation, promoter escape, and RNA elongation.Structural basis of transcription activation Coupling of downstream RNA polymerase-promoter interactions with formation of catalytically competent transcription initiation complex.Structural biology of bacterial RNA polymerase.A critical role of downstream RNA polymerase-promoter interactions in the formation of initiation complex.The β subunit gate loop is required for RNA polymerase modification by RfaH and NusG.A detailed study of antibacterial 3-acyltetramic acids and 3-acylpiperidine-2,4-diones.Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles.CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.Corallopyronin A specifically targets and depletes essential obligate Wolbachia endobacteria from filarial nematodes in vivo.Bacterial Transcription as a Target for Antibacterial Drug Development.TFE and Spt4/5 open and close the RNA polymerase clamp during the transcription cycle Allosteric control of Escherichia coli rRNA promoter complexes by DksA.Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP.CBR antimicrobials alter coupling between the bridge helix and the β subunit in RNA polymerase.Bacterial transcription terminators: the RNA 3'-end chronicles.How to cope with the quest for new antibiotics.Screening strategies for discovery of antibacterial natural products.Archaeology of RNA polymerase: factor swapping during the transcription cycle.Total synthesis of antibiotics: recent achievements, limitations, and perspectives.

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The RNA polymerase "switch region" is a target for inhibitors

http://www.wikidata.org/entity/Q24643039

description

2008 nî lūn-bûn

@nan

2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

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2008年論文

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2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

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2008年論文

@zh-tw

2008年论文

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name

The RNA polymerase "switch region" is a target for inhibitors

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The RNA polymerase "switch region" is a target for inhibitors

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The RNA polymerase "switch region" is a target for inhibitors

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The RNA polymerase "switch region" is a target for inhibitors

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The RNA polymerase "switch region" is a target for inhibitors

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The RNA Polymerase “Switch Region” Is a Target for Inhibitors

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The RNA polymerase "switch region" is a target for inhibitors

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The RNA polymerase "switch region" is a target for inhibitors

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The RNA polymerase "switch region" is a target for inhibitors

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The RNA polymerase "switch region" is a target for inhibitors

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David Koppstein

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Sajida Ismail

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Steven Tuske

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P2860

Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation

Structural mechanism for rifampicin inhibition of bacterial rna polymerase

Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution

Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution

Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 A resolution

Structural basis of transcription initiation: RNA polymerase holoenzyme at 4 A resolution

Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex

Structural basis for transcription elongation by bacterial RNA polymerase

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

Protein-nucleic acid interactions during open complex formation investigated by systematic alteration of the protein and DNA binding partners.

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