Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks
about
Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cellsEfficient construction of sequence-specific TAL effectors for modulating mammalian transcriptionTargeting serous epithelial ovarian cancer with designer zinc finger transcription factorsTunable and multifunctional eukaryotic transcription factors based on CRISPR/CasTherapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificitiesPositive and negative regulation of endogenous genes by designed transcription factorsTargeted genome editing in human cells with zinc finger nucleases constructed via modular assemblyToward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequencesZinc Finger Tools: custom DNA-binding domains for transcription factors and nucleasesHighly specific zinc finger proteins obtained by directed domain shuffling and cell-based selectionDiscovery of active proteins directly from combinatorial randomized protein libraries without display, purification or sequencing: identification of novel zinc finger proteinsUpdate on HER-2 as a target for cancer therapy: the ERBB2 promoter and its exploitation for cancer treatmentGenome-editing Technologies for Gene and Cell TherapyApplications of CRISPR-Cas systems in neuroscienceOrigins of Programmable Nucleases for Genome EngineeringEnabling functional genomics with genome engineeringStrategies for precision modulation of gene expression by epigenome editing: an overviewThe New State of the Art: Cas9 for Gene Activation and RepressionGenetic and genomic toolbox of the chordate Ciona intestinalisExpanding the scope of site-specific recombinases for genetic and metabolic engineeringMaking designer mutants in model organismsProgress and prospects of engineered sequence-specific DNA modulating technologies for the management of liver diseasesThe prospect of molecular therapy for Angelman syndrome and other monogenic neurologic disordersNucleosome distortion as a possible mechanism of transcription activation domain functionGene therapy for hemophiliaDevelopment of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factorsEngineering polydactyl zinc-finger transcription factorsSynthetic reversal of epigenetic silencingRational design of memory in eukaryotic cellsDevelopment of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factorsSynthetic memory circuits for tracking human cell fateDirected evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleasesRNA-guided gene activation by CRISPR-Cas9-based transcription factorsOptical control of mammalian endogenous transcription and epigenetic statesZFN, TALEN, and CRISPR/Cas-based methods for genome engineeringCRISPR RNA-guided activation of endogenous human genesZinc-binding cysteines: diverse functions and structural motifs.Zinc-finger-based transcriptional repression of rhodopsin in a model of dominant retinitis pigmentosa.Investigating and Engineering Enzymes by Genetic Selection.Scanning the human genome with combinatorial transcription factor libraries.
P2860
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P2860
Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Toward controlling gene expres ...... d from modular building blocks
@ast
Toward controlling gene expres ...... d from modular building blocks
@en
Toward controlling gene expres ...... d from modular building blocks
@nl
type
label
Toward controlling gene expres ...... d from modular building blocks
@ast
Toward controlling gene expres ...... d from modular building blocks
@en
Toward controlling gene expres ...... d from modular building blocks
@nl
prefLabel
Toward controlling gene expres ...... d from modular building blocks
@ast
Toward controlling gene expres ...... d from modular building blocks
@en
Toward controlling gene expres ...... d from modular building blocks
@nl
P2093
P2860
P3181
P356
P1476
Toward controlling gene expres ...... d from modular building blocks
@en
P2093
P2860
P304
14628-14633
P3181
P356
10.1073/PNAS.95.25.14628
P407
P577
1998-12-01T00:00:00Z