Zinc-finger-based transcriptional repression of rhodopsin in a model of dominant retinitis pigmentosa. - Wikidata - awgldk - TriplyDB

Zinc-finger-based transcriptional repression of rhodopsin in a model of dominant retinitis pigmentosa.

Zinc-finger-based transcriptional repression of rhodopsin in a model of dominant retinitis pigmentosa.

http://www.wikidata.org/entity/Q30499972

about

Synthetic biology and therapeutic strategies for the degenerating brain: Synthetic biology approaches can transform classical cell and gene therapies, to provide new cures for neurodegenerative diseases Gene therapy of inherited retinal degenerations: prospects and challenges A comprehensive review of retinal gene therapy Functional and molecular characterization of rod-like cells from retinal stem cells derived from the adult ciliary epithelium Optogenetic therapy for retinitis pigmentosa.Gene augmentation for adRP mutations in RHO.Gene therapy for PRPH2-associated ocular disease: challenges and prospects Vector platforms for gene therapy of inherited retinopathies.Recombinant vectors based on porcine adeno-associated viral serotypes transduce the murine and pig retina The Krüppel-associated box repressor domain can induce reversible heterochromatization of a mouse locus in vivo.Gene therapy of inherited retinopathies: a long and successful road from viral vectors to patients.Rhodopsin targeted transcriptional silencing by DNA-binding.Allele-Specific Inhibition of Rhodopsin With an Antisense Oligonucleotide Slows Photoreceptor Cell Degeneration Nrl knockdown by AAV-delivered CRISPR/Cas9 prevents retinal degeneration in mice.Gene-based therapies for dominantly inherited retinopathies.Clinical and Rehabilitative Management of Retinitis Pigmentosa: Up-to-Date.Gene therapy in animal models of autosomal dominant retinitis pigmentosa Gene therapies for inherited retinal disorders.Gene therapy to rescue retinal degeneration caused by mutations in rhodopsin.In Vivo CRISPR/Cas9 Gene Editing Corrects Retinal Dystrophy in the S334ter-3 Rat Model of Autosomal Dominant Retinitis Pigmentosa.A designed zinc-finger transcriptional repressor of phospholamban improves function of the failing heart.Gene delivery to the retina: from mouse to man.Long-term rescue of retinal structure and function by rhodopsin RNA replacement with a single adeno-associated viral vector in P23H RHO transgenic mice.In vivo Editing of the Human Mutant Rhodopsin Gene by Electroporation of Plasmid-based CRISPR/Cas9 in the Mouse Retina.Targeting and silencing of rhodopsin by ectopic expression of the transcription factor KLF15.Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells.

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Zinc-finger-based transcriptional repression of rhodopsin in a model of dominant retinitis pigmentosa.

http://www.wikidata.org/entity/Q30499972

description

2011 nî lūn-bûn

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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

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name

Zinc-finger-based transcriptio ...... dominant retinitis pigmentosa.

@ast

Zinc-finger-based transcriptio ...... dominant retinitis pigmentosa.

@en

type

label

Zinc-finger-based transcriptio ...... dominant retinitis pigmentosa.

@ast

Zinc-finger-based transcriptio ...... dominant retinitis pigmentosa.

@en

prefLabel

Zinc-finger-based transcriptio ...... dominant retinitis pigmentosa.

@ast

Zinc-finger-based transcriptio ...... dominant retinitis pigmentosa.

@en

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P1433

EMBO Molecular Medicine

P1476

Zinc-finger-based transcriptio ...... dominant retinitis pigmentosa.

@en

P2093

Ciro Bonetti

http://www.w3.org/2001/XMLSchema#string

Claudio Mussolino

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Daniela Sanges

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Elena Marrocco

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Germana Meroni

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Umberto Di Vicino

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P2860

The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression

On the genetics of retinitis pigmentosa and on mutation-independent approaches to therapeutic intervention

Krüppel-associated boxes are potent transcriptional repression domains

Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial

Safety and efficacy of gene transfer for Leber's congenital amaurosis

Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases

Development of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factors

Crx, a novel Otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genes

P304

118-128

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scholarly article

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10.1002/EMMM.201000119

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3

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3

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Enrico M. Surace

Alberto Auricchio

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2011-01-26T00:00:00Z

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49786669

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21268285

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3085076

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