The serine and threonine residues in the Ig-alpha cytoplasmic tail negatively regulate immunoreceptor tyrosine-based activation motif-mediated signal transduction
about
The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathwaysSyk is a dual-specificity kinase that self-regulates the signal output from the B-cell antigen receptorInterference with immunoglobulin (Ig)alpha immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igbeta cytoplasmic tailStructural and genetic basis for development of broadly neutralizing influenza antibodiesThe mouse B cell-specific mb-1 gene encodes an immunoreceptor tyrosine-based activation motif (ITAM) protein that may be evolutionarily conserved in diverse species by purifying selection.Cytoplasmic Ig alpha serine/threonines fine-tune Ig alpha tyrosine phosphorylation and limit bone marrow plasma cell formation.Ig beta tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization.Multitasking of Ig-alpha and Ig-beta to regulate B cell antigen receptor function.Piecing together the family portrait of TCR-CD3 complexes.Somatic hypermutation of the B cell receptor genes B29 (Igbeta, CD79b) and mb1 (Igalpha, CD79a).B-cell antigen-receptor signalling in lymphocyte development.Ligand-independent signaling functions for the B lymphocyte antigen receptor and their role in positive selection during B lymphopoiesis.Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation.In vitro reconstitution of B cell receptor-antigen interactions to evaluate potential vaccine candidates.Activation of T cells via tumor antigen specific chimeric receptors: the role of the intracellular signaling domain.The safety on the TCR trigger.Rottlerin-independent attenuation of pervanadate-induced tyrosine phosphorylation events by protein kinase C-delta in hemopoietic cells.Dectin-1 intracellular domain determines species-specific ligand spectrum by modulating receptor sensitivity.
P2860
Q24537242-A3DCF028-AD98-404A-B177-1D7138D6E437Q24615504-FCF20A50-8FE2-49DB-8255-A2FE1EBE27DEQ24675475-9621FEB7-316F-4E21-9671-CA7FF3D53966Q27682070-BAAB4367-BA92-4905-8917-E78B182CB14DQ34193922-A81F2FD6-7F56-43A1-BCEE-8EB124FD1FB7Q34207963-CB11B559-5CB0-4BCC-93A8-3A78E2B199BCQ34544332-18D76154-7B5F-4E79-BC26-5E1DB586C30FQ34577047-5ABCD520-BB56-4519-B033-D0599FE8EB35Q34643623-1BA481C4-7137-4320-80CD-BD4936E00F09Q34922043-B0F908C9-2EEE-4FFB-96E9-7DDF7B2CF70DQ35591032-B6D0FE81-E33F-4ACC-84A2-89F2E40593DAQ36369634-30CE8755-5B1F-4D13-B41C-E8190A545AE8Q37380010-135C7862-E678-4AA4-B3A7-E32202A9EA75Q38805907-10E3F75B-58A5-40DA-94F3-8A00E3367B88Q40684707-9F4B45EE-60A6-47C5-B934-3AB576D5D1EEQ42727833-0C844162-4C0C-4C4F-943D-30480A8753B1Q43705714-9BDF4A30-DB8A-4BB0-A705-51EB6B376B90Q46315429-C0E5DB7F-0BE1-48E8-9FA3-EF7EFFB701DC
P2860
The serine and threonine residues in the Ig-alpha cytoplasmic tail negatively regulate immunoreceptor tyrosine-based activation motif-mediated signal transduction
description
2000 nî lūn-bûn
@nan
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
name
The serine and threonine resid ...... f-mediated signal transduction
@ast
The serine and threonine resid ...... f-mediated signal transduction
@en
The serine and threonine resid ...... f-mediated signal transduction
@nl
type
label
The serine and threonine resid ...... f-mediated signal transduction
@ast
The serine and threonine resid ...... f-mediated signal transduction
@en
The serine and threonine resid ...... f-mediated signal transduction
@nl
prefLabel
The serine and threonine resid ...... f-mediated signal transduction
@ast
The serine and threonine resid ...... f-mediated signal transduction
@en
The serine and threonine resid ...... f-mediated signal transduction
@nl
P2093
P2860
P3181
P356
P1476
The serine and threonine resid ...... f-mediated signal transduction
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.97.15.8451
P407
P577
2000-07-18T00:00:00Z