Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha-mediated improvement of hepatic lipid profile

Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha-mediated improvement of hepatic lipid profile

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http://www.wikidata.org/entity/Q24647173
Group X secretory phospholipase A2 negatively regulates ABCA1 and ABCG1 expression and cholesterol efflux in macrophagesControlling cholesterol synthesis beyond 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR)Reduced VLDL clearance in Apoe(-/-)Npc1(-/-) mice is associated with increased Pcsk9 and Idol expression and decreased hepatic LDL-receptor levels.2,3-Oxidosqualene cyclase protects liver cells from the injury of intermittent hypoxia by regulating lipid metabolism.Dysregulation of Plasmalogen Homeostasis Impairs Cholesterol Biosynthesis.Cholesterol synthesis-related enzyme oxidosqualene cyclase is required to maintain self-renewal in primary erythroid progenitors.Squalene promotes cholesterol homeostasis in macrophage and hepatocyte cells via activation of liver X receptor (LXR) α and β.
P2860

Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha-mediated improvement of hepatic lipid profile

Item
http://www.wikidata.org/entity/Q24647173
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Suppression of 2,3-oxidosquale ...... ement of hepatic lipid profile
@ast
Suppression of 2,3-oxidosquale ...... ement of hepatic lipid profile
@en
Suppression of 2,3-oxidosquale ...... ement of hepatic lipid profile
@nl
type
label
Suppression of 2,3-oxidosquale ...... ement of hepatic lipid profile
@ast
Suppression of 2,3-oxidosquale ...... ement of hepatic lipid profile
@en
Suppression of 2,3-oxidosquale ...... ement of hepatic lipid profile
@nl
prefLabel
Suppression of 2,3-oxidosquale ...... ement of hepatic lipid profile
@ast
Suppression of 2,3-oxidosquale ...... ement of hepatic lipid profile
@en
Suppression of 2,3-oxidosquale ...... ement of hepatic lipid profile
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
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P1433
P1476
Suppression of 2,3-oxidosquale ...... ement of hepatic lipid profile
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932