Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent islets - Wikidata - awgldk - TriplyDB

Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent islets

Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent islets

http://www.wikidata.org/entity/Q24649735

about

Phosphoenolpyruvate cycling via mitochondrial phosphoenolpyruvate carboxykinase links anaplerosis and mitochondrial GTP with insulin secretion Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion The mitochondrial isoform of phosphoenolpyruvate carboxykinase (PEPCK-M) and glucose homeostasis: has it been overlooked?Lower succinyl-CoA:3-ketoacid-CoA transferase (SCOT) and ATP citrate lyase in pancreatic islets of a rat model of type 2 diabetes: knockdown of SCOT inhibits insulin release in rat insulinoma cells Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles Liver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling.The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion.Regulation of insulin secretion: role of mitochondrial signalling.ß-Cell-specific pyruvate dehydrogenase deficiency impairs glucose-stimulated insulin secretion Evaluation of the INS-1 832/13 cell line as a beta-cell based screening system to assess pollutant effects on beta-cell function.A role for cytosolic isocitrate dehydrogenase as a negative regulator of glucose signaling for insulin secretion in pancreatic ß-cells.Mitochondrial malic enzyme 3 is important for insulin secretion in pancreatic β-cells Induction of miR-132 and miR-212 Expression by Glucagon-Like Peptide 1 (GLP-1) in Rodent and Human Pancreatic β-Cells.Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells Direct Stimulation of Islet Insulin Secretion by Glycolytic and Mitochondrial Metabolites in KCl-Depolarized Islets.In vivo, cardiac-specific knockdown of a target protein, malic enzyme-1, in rat via adenoviral delivery of DNA for non-native miRNA.Metabolic cycling in control of glucose-stimulated insulin secretion Control of voltage-gated potassium channel Kv2.2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion.Metabolomics applied to diabetes research: moving from information to knowledge Chronic reduction of the cytosolic or mitochondrial NAD(P)-malic enzyme does not affect insulin secretion in a rat insulinoma cell line.The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism: Going round in circles?Overcoming the spatial barriers of the stimulus secretion cascade in pancreatic β-cells.β-Cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion.Adenylosuccinate Is an Insulin Secretagogue Derived from Glucose-Induced Purine Metabolism.The Pancreatic β-Cell: A Bioenergetic Perspective.Fuel-Stimulated Insulin Secretion Depends upon Mitochondria Activation and the Integration of Mitochondrial and Cytosolic Substrate Cycles Metabolomic analysis of pancreatic β-cell insulin release in response to glucose.Aryl hydrocarbon receptor nuclear translocator/hypoxia-inducible factor-1{beta} plays a critical role in maintaining glucose-stimulated anaplerosis and insulin release from pancreatic {beta}-cells.Silencing of the mitochondrial NADH shuttle component aspartate-glutamate carrier AGC1/Aralar1 in INS-1E cells and rat islets.Mitochondrial malic enzyme (ME2) in pancreatic islets of the human, rat and mouse and clonal insulinoma cells Transcribing β-cell mitochondria in health and disease.Integrated, Step-Wise, Mass-Isotopomeric Flux Analysis of the TCA Cycle.Hetero-bivalent GLP-1/glibenclamide for targeting pancreatic β-cells.How do reducing equivalents increase insulin secretion?Time-resolved metabolomics analysis of β-cells implicates the pentose phosphate pathway in the control of insulin release.miR-494 protects pancreatic β-cell function by targeting PTEN in gestational diabetes mellitus.

P2860

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P2860

Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent islets

http://www.wikidata.org/entity/Q24649735

description

2008 nî lūn-bûn

@nan

2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

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2008年論文

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2008年論文

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2008年論文

@zh-hk

2008年論文

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2008年論文

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2008年论文

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name

Silencing of cytosolic or mito ...... n secretion from rodent islets

@ast

Silencing of cytosolic or mito ...... n secretion from rodent islets

@en

Silencing of cytosolic or mito ...... n secretion from rodent islets

@nl

type

label

Silencing of cytosolic or mito ...... n secretion from rodent islets

@ast

Silencing of cytosolic or mito ...... n secretion from rodent islets

@en

Silencing of cytosolic or mito ...... n secretion from rodent islets

@nl

prefLabel

Silencing of cytosolic or mito ...... n secretion from rodent islets

@ast

Silencing of cytosolic or mito ...... n secretion from rodent islets

@en

Silencing of cytosolic or mito ...... n secretion from rodent islets

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

Silencing of cytosolic or mito ...... n secretion from rodent islets

@en

P2093

A Dean Sherry

http://www.w3.org/2001/XMLSchema#string

Andrew Howard

http://www.w3.org/2001/XMLSchema#string

Christopher B Newgard

http://www.w3.org/2001/XMLSchema#string

Danhong Lu

http://www.w3.org/2001/XMLSchema#string

Douglas MacNeil

http://www.w3.org/2001/XMLSchema#string

Hans E Hohmeier

http://www.w3.org/2001/XMLSchema#string

Mette V Jensen

http://www.w3.org/2001/XMLSchema#string

Nancy Thornberry

http://www.w3.org/2001/XMLSchema#string

Olga Ilkayeva

http://www.w3.org/2001/XMLSchema#string

Sarah M Ronnebaum

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P2860

13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS)

Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism

Elimination of KATP channels in mouse islets results in elevated [U-13C]glucose metabolism, glutaminolysis, and pyruvate cycling but a decreased gamma-aminobutyric acid shunt

A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion

Feasibility of pathways for transfer of acyl groups from mitochondria to the cytosol to form short chain acyl-CoAs in the pancreatic beta cell

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction.

Biochemical mechanism of lipid-induced impairment of glucose-stimulated insulin secretion and reversal with a malate analogue.

Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells.

Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion.

P304

28909-17

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scholarly article

P356

10.1074/JBC.M804665200

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P407

P433

43

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P478

283

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2008-10-24T00:00:00Z

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18755687

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P932

2570884

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