Human VPS34 is required for internal vesicle formation within multivesicular endosomes - Wikidata - awgldk - TriplyDB

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

http://www.wikidata.org/entity/Q24652429

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PIKfyve controls fluid phase endocytosis but not recycling/degradation of endocytosed receptors or sorting of procathepsin D by regulating multivesicular body morphogenesis Human VPS34 and p150 are Rab7 interacting partners Sorting nexin 10 induces giant vacuoles in mammalian cells Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9 PI(5)P regulates autophagosome biogenesis PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49 ATPase-deficient hVPS4 impairs formation of internal endosomal vesicles and stabilizes bilayered clathrin coats on endosomal vacuoles Rab27a and Rab27b control different steps of the exosome secretion pathway Sorting nexin 17 accelerates internalization yet retards degradation of P-selectin Biogenesis and function of multivesicular bodies hVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cells Hrs regulates early endosome fusion by inhibiting formation of an endosomal SNARE complex The C2 domain of the Rsp5 ubiquitin ligase binds membrane phosphoinositides and directs ubiquitination of endosomal cargo Release of autoinhibition converts ESCRT-III components into potent inhibitors of HIV-1 budding Exosome Biogenesis, Regulation, and Function in Viral Infection Class III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane traffic Endosome maturation Phosphoinositides in the mammalian endo-lysosomal network Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion.Termination of isoform-selective Vps21/Rab5 signaling at endolysosomal organelles by Msb3/Gyp3.Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins Localized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusion Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity.Compartmental signal modulation: Endosomal phosphatidylinositol 3-phosphate controls endosome morphology and selective cargo sorting.Endosomal compartmentalization in three dimensions: implications for membrane fusion The role of ubiquitination in lysosomal trafficking of δ-opioid receptors.Protein kinase D1/2 is involved in the maturation of multivesicular bodies and secretion of exosomes in T and B lymphocytes Membrane protein location-dependent regulation by PI3K (III) and rabenosyn-5 in Drosophila wing cells.The microtubule-associated histone deacetylase 6 (HDAC6) regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation.The mammalian class 3 PI3K (PIK3C3) is required for early embryogenesis and cell proliferation.ARHI (DIRAS3) induces autophagy in ovarian cancer cells by downregulating the epidermal growth factor receptor, inhibiting PI3K and Ras/MAP signaling and activating the FOXo3a-mediated induction of Rab7 Large-scale profiling of Rab GTPase trafficking networks: the membrome.Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway Molecular Mechanisms that Regulate Epidermal Growth Factor Receptor Inactivation Crimean-Congo hemorrhagic fever virus entry into host cells occurs through the multivesicular body and requires ESCRT regulators

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P2860

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

http://www.wikidata.org/entity/Q24652429

description

2001 nî lūn-bûn

@nan

2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

@ast

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

@en

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

@nl

type

label

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

@ast

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

@en

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

@nl

prefLabel

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

@ast

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

@en

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

@nl

P1433

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P2860

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P1433

Journal of Cell Biology

P1476

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

@en

P2093

C E Futter

http://www.w3.org/2001/XMLSchema#string

C R Hopkins

http://www.w3.org/2001/XMLSchema#string

J M Backer

http://www.w3.org/2001/XMLSchema#string

L M Collinson

http://www.w3.org/2001/XMLSchema#string

P2860

Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain

SNX3 regulates endosomal function through its PX-domain-mediated interaction with PtdIns(3)P

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

Hrs recruits clathrin to early endosomes

Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes

Fusion of lysosomes with late endosomes produces a hybrid organelle of intermediate density and is NSF dependent

Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting

Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.

FYVE-finger proteins--effectors of an inositol lipid

P304

1251-64

http://www.w3.org/2001/XMLSchema#string

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scholarly article

P3181

4557951

http://www.w3.org/2001/XMLSchema#string

P356

10.1083/JCB.200108152

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P407

P433

7

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P478

155

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2001-12-24T00:00:00Z

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11602105

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P698

11756475

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P932

2199316

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