Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation. - Wikidata - awgldk - TriplyDB

Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation.

Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation.

http://www.wikidata.org/entity/Q34049104

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Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4 Prostaglandin E receptor type 4-associated protein interacts directly with NF-kappaB1 and attenuates macrophage activation The Alternative Faces of Macrophage Generate Osteoclasts E-type prostanoid receptor 4 (EP4) in disease and therapy P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesis Mechanical strain regulates osteoblast proliferation through integrin-mediated ERK activation A comparison of the effects of ibuprofen and rofecoxib on rabbit fibula osteotomy healing.Prostaglandin E2 inhibits matrix mineralization by human bone marrow stromal cell-derived osteoblasts via Epac-dependent cAMP signaling Prostaglandins in bone: bad cop, good cop?Prostaglandin E2 promotes human CD34+ cells homing through EP2 and EP4 in vitro.Beta1 integrins mediate mechanosensitive signaling pathways in osteocytes Hypoxia regulates PGE(2) release and EP1 receptor expression in osteoblastic cells.Novel early response genes in osteoblasts exposed to dynamic fluid flow Prostaglandin E(2) receptors in bone formation.Basal bone phenotype and increased anabolic responses to intermittent parathyroid hormone in healthy male COX-2 knockout mice.Targeting rheumatoid inflammation and joint destruction in the mouse.Immunohistochemical localization of key arachidonic acid metabolism enzymes during fracture healing in mice.Prostaglandin E₂-EP4 signaling suppresses adipocyte differentiation in mouse embryonic fibroblasts via an autocrine mechanism Role of prostaglandin pathway and alendronate-based carriers to enhance statin-induced bone.Expression of ATF4 and RUNX2 in periodontal tissue of pressure side during orthodontic tooth movement in rat.Gsα enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice.Absence of platelet-activating factor receptor protects mice from osteoporosis following ovariectomy.Loss of the PGE2 receptor EP1 enhances bone acquisition, which protects against age and ovariectomy-induced impairments in bone strength.Reduced COX-2 expression in aged mice is associated with impaired fracture healing.Peroxisomes in Different Skeletal Cell Types during Intramembranous and Endochondral Ossification and Their Regulation during Osteoblast Differentiation by Distinct Peroxisome Proliferator-Activated Receptors.GPR120: A bi-potential mediator to modulate the osteogenic and adipogenic differentiation of BMMSCs PTGER4 gene variant rs76523431 is a candidate risk factor for radiological joint damage in rheumatoid arthritis patients: a genetic study of six cohorts.Age-related changes in bone morphology are accelerated in group VIA phospholipase A2 (iPLA2beta)-null mice IL-23/Th17 axis is not influenced by TNF-blocking agents in ankylosing spondylitis patients The roles of cyclooxygenase-2 and prostaglandin E2 in periodontal disease.Low dose aspirin therapy decreases blood glucose levels but does not prevent type i diabetes-induced bone loss In vitro and in vivo evidence for stimulation of bone resorption by an EP4 receptor agonist and basic fibroblast growth factor: Implications for their efficacy as bone anabolic agents.Rescue of impaired fracture healing in COX-2-/- mice via activation of prostaglandin E2 receptor subtype 4.Physiology and pathophysiology of prostanoid receptors.In vivo prostaglandin E2 treatment alters the bone marrow microenvironment and preferentially expands short-term hematopoietic stem cells.Small molecules for bone diseases.Phosphatidylserine-containing liposomes: potential pharmacological interventions against inflammatory and immune diseases through the production of prostaglandin E(2) after uptake by myeloid derived phagocytes.PGE₂ and BMP-2 in bone and cartilage metabolism: 2 intertwining pathways.The multiple faces of prostaglandin E2 G-protein coupled receptor signaling during the dendritic cell life cycle.Bone quality: the determinants of bone strength and fragility.

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Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation.

http://www.wikidata.org/entity/Q34049104

description

2002 nî lūn-bûn

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2002 թուականի Մարտին հրատարակուած գիտական յօդուած

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2002 թվականի մարտին հրատարակված գիտական հոդված

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2002年の論文

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Stimulation of bone formation ...... din E EP4 receptor activation.

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Stimulation of bone formation ...... din E EP4 receptor activation.

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Stimulation of bone formation ...... din E EP4 receptor activation.

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Stimulation of bone formation ...... din E EP4 receptor activation.

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Stimulation of bone formation ...... din E EP4 receptor activation.

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Stimulation of bone formation ...... din E EP4 receptor activation.

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Stimulation of bone formation ...... din E EP4 receptor activation.

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Stimulation of bone formation ...... din E EP4 receptor activation.

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Stimulation of bone formation ...... din E EP4 receptor activation.

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Proceedings of the National Academy of Sciences of the United States of America

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Stimulation of bone formation ...... din E EP4 receptor activation.

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Eri Segi

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Fumitaka Ushikubi

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Hiroji Oida

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Keiji Yoshida

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Kigen Kondo

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Kojiro Yamaguchi

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Kosei Ito

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Masaharu Tanaka

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Mutsumi Matsushita

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Shuh Narumiya

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P2860

Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP(2)

Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis 1

A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia

The role of prostaglandin E receptor subtypes (EP1, EP2, EP3, and EP4) in bone resorption: an analysis using specific agonists for the respective EPs

Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3

Impaired bone resorption to prostaglandin E2 in prostaglandin E receptor EP4-knockout mice

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

Prostanoid receptors: structures, properties, and functions

Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis

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4580-4585

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10.1073/PNAS.062053399

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7

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99

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11917107

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