Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias
about
Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6.t(11;22)(q23;q11.2) In acute myeloid leukemia of infant twins fuses MLL with hCDCrel, a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromesDetection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitorsHuman LPP gene is fused to MLL in a secondary acute leukemia with a t(3;11) (q28;q23)Roles of retrotransposons in benign and malignant hematologic disease.Diagnostic tool for the identification of MLL rearrangements including unknown partner genesNear-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocationGenomic inverse PCR for exploration of ligated breakpoints (GIPFEL), a new method to detect translocations in leukemiaLeukemias related to treatment with DNA topoisomerase II inhibitors.Therapy related leukemias: susceptibility, prevention and treatment.Therapy-related acute lymphoblastic leukaemia with MLL rearrangements following DNA topoisomerase II inhibitors, an increasing problem: report on two new cases and review of the literature since 1992.Translocation t(X;11)(q13;q23) in B-cell chronic lymphocytic leukemia disrupts two novel genes.Proteomic identification of oncogenic chromosomal translocation partners encoding chimeric anaplastic lymphoma kinase fusion proteins.The role of Alu repeat clusters as mediators of recurrent chromosomal aberrations in tumors.Panhandle PCR for cDNA: a rapid method for isolation of MLL fusion transcripts involving unknown partner genes.Split-signal FISH for detection of chromosome aberrations in acute lymphoblastic leukemia.The MLL partial tandem duplication: evidence for recessive gain-of-function in acute myeloid leukemia identifies a novel patient subgroup for molecular-targeted therapySplit-signal FISH for detection of chromosome aberrations.Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndromeMass spectrometry-based proteomic studies of human anaplastic large cell lymphoma.Association of CYP3A4 genotype with treatment-related leukemia.Antileukemic Scalarane Sesterterpenoids and Meroditerpenoid from Carteriospongia (Phyllospongia) sp., Induce Apoptosis via Dual Inhibitory Effects on Topoisomerase II and Hsp90.Topoisomerase II and leukemia.Cryptic insertion of PML-RARA into the 3p25 locus in an acute promyelocytic leukemia with t(3;17)(p25;q21)Reciprocal DNA topoisomerase II cleavage events at 5'-TATTA-3' sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further process
P2860
Q24536146-87BF5467-29AA-4EF9-8BFF-218C1FB13E94Q24641962-18378FEE-F136-4980-9318-BBDBB7DED282Q24676265-8740E708-95F3-4F73-A98F-FBFF8E38B683Q28204405-52A75B9D-678C-45A7-ADF9-7AC9CA01B7C6Q33697456-506A4CE5-6800-4EE6-A571-ABFA05342F74Q33723050-6BD79429-2008-433D-9B1A-5C739546C6F1Q33933823-EF26DB70-6445-4959-A4FA-DACEB1799FC8Q34066349-CF79BBF4-497C-45F6-8A22-B200DD9EAFFEQ34243503-C4C4112A-A987-48BF-9943-326F51D12932Q34265193-5A85EFD3-DA2E-49F1-9790-C50B3093EB97Q34366002-610CABE0-BEC3-40F1-98E5-7EAFC5470646Q34367685-AC274477-C560-423D-B817-16D48B1F1359Q34624556-C750BDA6-0177-4106-923F-A93B722A9779Q34804028-717382CE-A9E4-47F3-A54A-DB6E997F284DQ35209776-9481B852-C428-4082-8003-0AC07B050059Q35712192-143FDB2C-AB87-4C50-BF27-9A4A02D6626BQ35847845-D6E746FF-87B9-48C0-AB28-5F3C00C55822Q36269955-60D32D08-5D6B-49CA-9C3D-3818DB6DA2DDQ36508959-ABB752D9-A0FA-4F41-8BCF-A69E8237A14EQ36511656-A685C1DA-030B-45A5-A50C-FE18E308EFA9Q36643196-3CCEE0B1-3EF2-4274-B1A5-10AAC7AFF944Q37379572-E8A6137B-9BDE-4748-8053-0215FC541550Q37652882-59EB5008-16B8-47CF-A430-17602D2A868BQ42528863-9E3F7DF9-BADE-4B39-9B79-4B60B3076F67Q44662281-4C4CD4EC-0BC7-4A65-9E40-2FEE4C32630D
P2860
Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias
@ast
Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias
@en
Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias
@nl
type
label
Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias
@ast
Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias
@en
Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias
@nl
prefLabel
Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias
@ast
Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias
@en
Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias
@nl
P2093
P2860
P3181
P356
P1476
Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias
@en
P2093
E F Rappaport
M D Megonigal
P C Nowell
P2860
P304
P3181
P356
10.1073/PNAS.94.21.11583
P407
P577
1997-10-14T00:00:00Z