The interaction of the carboxyl terminus-binding protein with the Smad corepressor TGIF is disrupted by a holoprosencephaly mutation in TGIF
about
The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif.Identification of PCTA, a TGIF antagonist that promotes PML function in TGF-beta signallingAn autoinhibitory effect of the homothorax domain of Meis2Overlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development.Nuclear speckle-associated protein Pnn/DRS binds to the transcriptional corepressor CtBP and relieves CtBP-mediated repression of the E-cadherin geneThe novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradationTgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation.Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteinsFunctional analysis of mutations in TGIF associated with holoprosencephaly.The Tgif2 gene contains a retained intron within the coding sequence.The TGF-β/Smad repressor TG-interacting factor 1 (TGIF1) plays a role in radiation-induced intestinal injury independently of a Smad signaling pathwayTGIF2 interacts with histone deacetylase 1 and represses transcriptionThe CtBP family: enigmatic and enzymatic transcriptional co-repressorsInteraction between FOG-1 and the corepressor C-terminal binding protein is dispensable for normal erythropoiesis in vivo.Embryonic fibroblasts from mice lacking Tgif were defective in cell cyclingPremature senescence and increased TGFβ signaling in the absence of Tgif1.TGIF inhibits retinoid signalingTranscriptome analysis of spermatogenically regressed, recrudescent and active phase testis of seasonally breeding wall lizards Hemidactylus flaviviridisRapid evolution of mammalian X-linked testis-expressed homeobox genesTgif1 and Tgif2 Repress Expression of the RabGAP Evi5l.Genetic and Molecular Analyses indicate independent effects of TGIFs on Nodal and Gli3 in neural tube patterning.Tgif1 and Tgif2 Regulate Axial Patterning in Mouse.Tgif1 represses apolipoprotein gene expression in liver.Inhibition of CtBP1 activity by Akt-mediated phosphorylation.Maternal Tgif is required for vascularization of the embryonic placentaDrosophila TGIF proteins are transcriptional activators.Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease.Targeted disruption of Tgif, the mouse ortholog of a human holoprosencephaly gene, does not result in holoprosencephaly in mice.Suv39h histone methyltransferases interact with Smads and cooperate in BMP-induced repression.Effects of transforming growth interacting factor on biological behaviors of gastric carcinoma cells.Adenovirus E1A: remodelling the host cell, a life or death experience.BmTGIF, a Bombyx mori homolog of Drosophila DmTGIF, regulates progression of spermatogenesis.Smad6 recruits transcription corepressor CtBP to repress bone morphogenetic protein-induced transcription.TGIF Mutations in Human Holoprosencephaly: Correlation between Genotype and PhenotypeMechanism study of peptide GMBP1 and its receptor GRP78 in modulating gastric cancer MDR by iTRAQ-based proteomic analysis.Default repression and Notch signaling: Hairless acts as an adaptor to recruit the corepressors Groucho and dCtBP to Suppressor of Hairless.The Role of CtBP1 in Oncogenic Processes and Its Potential as a Therapeutic Target.Dissection of the C-terminal region of E1A redefines the roles of CtBP and other cellular targets in oncogenic transformation.Functional similarity of Knirps CtBP-dependent and CtBP-independent transcriptional repressor activities.Corepressor CtBP and nuclear speckle protein Pnn/DRS differentially modulate transcription and splicing of the E-cadherin gene.
P2860
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P2860
The interaction of the carboxyl terminus-binding protein with the Smad corepressor TGIF is disrupted by a holoprosencephaly mutation in TGIF
description
2000 nî lūn-bûn
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2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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The interaction of the carboxy ...... prosencephaly mutation in TGIF
@ast
The interaction of the carboxy ...... prosencephaly mutation in TGIF
@en
The interaction of the carboxy ...... prosencephaly mutation in TGIF
@nl
type
label
The interaction of the carboxy ...... prosencephaly mutation in TGIF
@ast
The interaction of the carboxy ...... prosencephaly mutation in TGIF
@en
The interaction of the carboxy ...... prosencephaly mutation in TGIF
@nl
prefLabel
The interaction of the carboxy ...... prosencephaly mutation in TGIF
@ast
The interaction of the carboxy ...... prosencephaly mutation in TGIF
@en
The interaction of the carboxy ...... prosencephaly mutation in TGIF
@nl
P2860
P3181
P356
P1476
The interaction of the carboxy ...... prosencephaly mutation in TGIF
@en
P2093
T A Melhuish
P2860
P304
P3181
P356
10.1074/JBC.C000416200
P407
P50
P577
2000-12-15T00:00:00Z