Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation - Wikidata - awgldk - TriplyDB

Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation

Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation

http://www.wikidata.org/entity/Q24657890

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A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P Dendritic spines elongate after stimulation of group 1 metabotropic glutamate receptors in cultured hippocampal neurons.Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function Group 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and disease A cellular mechanism for targeting newly synthesized mRNAs to synaptic sites on dendrites A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome.Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits Molecular and cognitive predictors of the continuum of autistic behaviours in fragile X Colocalization of integrin receptors and reelin in dendritic spine postsynaptic densities of adult nonhuman primate cortex Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice.The gene encoding the fragile X RNA-binding protein is controlled by nuclear respiratory factor 2 and the CREB family of transcription factors.Dendritic mRNAs encode diversified functionalities in hippocampal pyramidal neurons Clinical and Neurobiological Relevance of Current Animal Models of Autism Spectrum Disorders.Single-Nucleotide Mutations in FMR1 Reveal Novel Functions and Regulatory Mechanisms of the Fragile X Syndrome Protein FMRP Emerging pharmacologic treatment options for fragile X syndrome Fragile X syndrome and targeted treatment trials.Dendritic spine dysgenesis in autism related disorders Unstable mutations in the FMR1 gene and the phenotypes The pathophysiology of fragile X (and what it teaches us about synapses)Channelopathies and dendritic dysfunction in fragile X syndrome.Regulatory BC1 RNA and the fragile X mental retardation protein: convergent functionality in brain Review of targeted treatments in fragile X syndrome G-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptome Fragile X mental retardation protein: A paradigm for translational control by RNA-binding proteins A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability In vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation protein Translational regulation of the human achaete-scute homologue-1 by fragile X mental retardation protein The fragile X gene and its function Identification of mRNA/protein (mRNP) complexes containing Puralpha, mStaufen, fragile X protein, and myosin Va and their association with rough endoplasmic reticulum equipped with a kinesin motor From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome Localization of FMRP-associated mRNA granules and requirement of microtubules for activity-dependent trafficking in hippocampal neurons The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif.Roles of fragile X mental retardation protein in dopaminergic stimulation-induced synapse-associated protein synthesis and subsequent alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-4-propionate (AMPA) receptor internalization Clustered coding variants in the glutamate receptor complexes of individuals with schizophrenia and bipolar disorder Positive feedback regulation of Akt-FMRP pathway protects neurons from cell death Transport of fragile X mental retardation protein via granules in neurites of PC12 cells.Exploring the zebra finch Taeniopygia guttata as a novel animal model for the speech-language deficit of fragile X syndrome Expression of fragile X mental retardation protein within the vocal control system of developing and adult male zebra finches Premutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding.Progress toward therapeutic potential for AFQ056 in Fragile X syndrome.

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P2860

Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation

http://www.wikidata.org/entity/Q24657890

description

1997 nî lūn-bûn

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1997 թուականի Մայիսին հրատարակուած գիտական յօդուած

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1997 թվականի մայիսին հրատարակված գիտական հոդված

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1997年の論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年论文

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name

Fragile X mental retardation p ...... to neurotransmitter activation

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Fragile X mental retardation p ...... to neurotransmitter activation

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Fragile X mental retardation p ...... to neurotransmitter activation

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label

Fragile X mental retardation p ...... to neurotransmitter activation

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Fragile X mental retardation p ...... to neurotransmitter activation

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Fragile X mental retardation p ...... to neurotransmitter activation

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Fragile X mental retardation p ...... to neurotransmitter activation

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Fragile X mental retardation p ...... to neurotransmitter activation

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Fragile X mental retardation p ...... to neurotransmitter activation

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Proceedings of the National Academy of Sciences of the United States of America

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Fragile X mental retardation p ...... to neurotransmitter activation

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A D Brazelton

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B Patel

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C M Spencer

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I J Weiler

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J Eberwine

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K Miyashiro

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S A Irwin

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T A Comery

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W T Greenough

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P2860

Essential role for KH domains in RNA binding: impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome

FXR1, an autosomal homolog of the fragile X mental retardation gene

Metabotropic glutamate receptors trigger postsynaptic protein synthesis

Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits

Three-dimensional structure and stability of the KH domain: molecular insights into the fragile X syndrome

Variation of the CGG repeat at the fragile X site results in genetic instability: resolution of the Sherman paradox

Characterization and localization of the FMR-1 gene product associated with fragile X syndrome

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

Metaplasticity: the plasticity of synaptic plasticity

Getting the message from the gene to the synapse: sorting and intracellular transport of RNA in neurons.

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