Rapid mapping of protein functional epitopes by combinatorial alanine scanning
about
O-Glycosylated 24 kDa human growth hormone has a mucin-like biantennary disialylated tetrasaccharide attached at Thr-60Origins of PDZ domain ligand specificity. Structure determination and mutagenesis of the Erbin PDZ domainStructural and functional analysis of the ligand specificity of the HtrA2/Omi PDZ domainStructural and functional analysis of the PDZ domains of human HtrA1 and HtrA3Comprehensive analysis of the factors contributing to the stability and solubility of autonomous human VH domainsToward chaperone-assisted crystallography: Protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffoldA Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein–Protein InterfacesDirected Evolution Reveals the Binding Motif Preference of the LC8/DYNLL Hub Protein and Predicts Large Numbers of Novel Binders in the Human ProteomeMolecular Basis of a Million-Fold Affinity Maturation Process in a Protein–Protein InteractionA combinatorial histidine scanning library approach to engineer highly pH-dependent protein switchesCDR-H3 Diversity Is Not Required for Antigen Recognition by Synthetic AntibodiesMonospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2Reshaping an enzyme binding pocket for enhanced and inverted stereoselectivity: use of smallest amino acid alphabets in directed evolutionIsolation of monobodies that bind specifically to the SH3 domain of the Fyn tyrosine protein kinase.Determination of binding affinity upon mutation for type I dockerin-cohesin complexes from Clostridium thermocellum and Clostridium cellulolyticum using deep sequencingThe scope of phage display for membrane proteins.Fine Epitope Mapping of Two Antibodies Neutralizing the Bordetella Adenylate Cyclase Toxin.Cross-Neutralising Nanobodies Bind to a Conserved Pocket in the Hemagglutinin Stem Region Identified Using Yeast Display and Deep Mutational Scanning.Rapid fine conformational epitope mapping using comprehensive mutagenesis and deep sequencing.A general method for scanning unnatural amino acid mutagenesis.Phage display of random peptide libraries: applications, limits, and potential.A phage display selection of engrailed homeodomain mutants and the importance of residue Q50.Sequence analysis of an artificial family of RNA-binding peptidesExploring protein-protein interactions with phage display.Predicting oligonucleotide-directed mutagenesis failures in protein engineering.Phage-display as a tool for quantifying protein stability determinants.Alternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis.Exploring the interaction between the protein kinase A catalytic subunit and caveolin-1 scaffolding domain with shotgun scanning, oligomer complementation, NMR, and dockingA protein interaction surface in nonribosomal peptide synthesis mapped by combinatorial mutagenesis and selection.Comprehensive and quantitative mapping of energy landscapes for protein-protein interactions by rapid combinatorial scanning.Fine and domain-level epitope mapping of botulinum neurotoxin type A neutralizing antibodies by yeast surface display.High-throughput analysis of the protein sequence-stability landscape using a quantitative yeast surface two-hybrid system and fragment reconstitutionNovel Bcl-2 homology-3 domain-like sequences identified from screening randomized peptide libraries for inhibitors of the pro-survival Bcl-2 proteins.Identification and characterization of beta-lactamase inhibitor protein-II (BLIP-II) interactions with beta-lactamases using phage display.Progress towards recombinant anti-infective antibodies.Contribution of light chain residues to high affinity binding in an HIV-1 antibody explored by combinatorial scanning mutagenesisHigh-resolution mapping of protein sequence-function relationships.Epitope mapping and key amino acid identification of anti-CD22 immunotoxin CAT-8015 using hybrid β-lactamase displayA mutate-and-map strategy accurately infers the base pairs of a 35-nucleotide model RNASynthetic approach to stop-codon scanning mutagenesis.
P2860
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P2860
Rapid mapping of protein functional epitopes by combinatorial alanine scanning
description
2000 nî lūn-bûn
@nan
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Rapid mapping of protein functional epitopes by combinatorial alanine scanning
@ast
Rapid mapping of protein functional epitopes by combinatorial alanine scanning
@en
Rapid mapping of protein functional epitopes by combinatorial alanine scanning
@nl
type
label
Rapid mapping of protein functional epitopes by combinatorial alanine scanning
@ast
Rapid mapping of protein functional epitopes by combinatorial alanine scanning
@en
Rapid mapping of protein functional epitopes by combinatorial alanine scanning
@nl
prefLabel
Rapid mapping of protein functional epitopes by combinatorial alanine scanning
@ast
Rapid mapping of protein functional epitopes by combinatorial alanine scanning
@en
Rapid mapping of protein functional epitopes by combinatorial alanine scanning
@nl
P2093
P2860
P3181
P356
P1476
Rapid mapping of protein functional epitopes by combinatorial alanine scanning
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.160252097
P407
P577
2000-08-01T00:00:00Z