Chimeric recombinases with designed DNA sequence recognition
about
Genome-scale engineering for systems and synthetic biologyHighly specific zinc finger proteins obtained by directed domain shuffling and cell-based selectionEnabling functional genomics with genome engineeringExpanding the scope of site-specific recombinases for genetic and metabolic engineeringCrystal structure of the bacteriophage P2 integrase catalytic domainMutants of Cre recombinase with improved accuracyZinc finger recombinases with adaptable DNA sequence specificityDirected evolution of recombinase specificity by split gene reassemblyModular system for the construction of zinc-finger libraries and proteins.Serine integrase chimeras with activity in E. coli and HeLa cells.Chimeric TALE recombinases with programmable DNA sequence specificityStructure-guided reprogramming of serine recombinase DNA sequence specificityTargeted plasmid integration into the human genome by an engineered zinc-finger recombinaseMeganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy.Redesigning Recombinase Specificity for Safe Harbor Sites in the Human GenomeGene therapy progress and prospects: targeted gene repair.Chimeric piggyBac transposases for genomic targeting in human cellsFinding of a highly efficient ZFN pair for Aqpep gene functioning in murine zygotesA comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cellsA chimeric Cre recombinase with regulated directionality.Synthesis of programmable integrases.A programmable Cas9-serine recombinase fusion protein that operates on DNA sequences in mammalian cellsExpanding the zinc-finger recombinase repertoire: directed evolution and mutational analysis of serine recombinase specificity determinants.Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign.Control of serine integrase recombination directionality by fusion with the directionality factor.Serine Resolvases.Manipulating piggyBac transposon chromosomal integration site selection in human cellsEvolution of variants of yeast site-specific recombinase Flp that utilize native genomic sequences as recombination target sites.Binding and catalytic contributions to site recognition by flp recombinase.Selection of bacteriophage lambda integrases with altered recombination specificity by in vitro compartmentalization.Zinc-finger recombinase activities in vitro.Genome engineering: a new approach to gene therapy for neuromuscular disorders.Synapsis and catalysis by activated Tn3 resolvase mutants.The Future of Multiplexed Eukaryotic Genome Engineering.Purification and In Vitro Characterization of Zinc Finger Recombinases.Engineering altered protein-DNA recognition specificity.Zinc-finger motif noncovalent interactions with double-stranded DNA characterized by negative-ion electrospray ionization mass spectrometry
P2860
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P2860
Chimeric recombinases with designed DNA sequence recognition
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Chimeric recombinases with designed DNA sequence recognition
@ast
Chimeric recombinases with designed DNA sequence recognition
@en
Chimeric recombinases with designed DNA sequence recognition
@nl
type
label
Chimeric recombinases with designed DNA sequence recognition
@ast
Chimeric recombinases with designed DNA sequence recognition
@en
Chimeric recombinases with designed DNA sequence recognition
@nl
prefLabel
Chimeric recombinases with designed DNA sequence recognition
@ast
Chimeric recombinases with designed DNA sequence recognition
@en
Chimeric recombinases with designed DNA sequence recognition
@nl
P2093
P2860
P3181
P356
P1476
Chimeric recombinases with designed DNA sequence recognition
@en
P2093
Aram Akopian
Martin R Boocock
P2860
P304
P3181
P356
10.1073/PNAS.1533177100
P407
P577
2003-07-01T00:00:00Z