Evolution of variants of yeast site-specific recombinase Flp that utilize native genomic sequences as recombination target sites. - Wikidata - awgldk - TriplyDB

Evolution of variants of yeast site-specific recombinase Flp that utilize native genomic sequences as recombination target sites.

Evolution of variants of yeast site-specific recombinase Flp that utilize native genomic sequences as recombination target sites.

http://www.wikidata.org/entity/Q39079092

about

Targeted DNA mutagenesis for the cure of chronic viral infections Expanding the scope of site-specific recombinases for genetic and metabolic engineering Unveiling hidden catalytic contributions of the conserved His/Trp-III in tyrosine recombinases: assembly of a novel active site in Flp recombinase harboring alanine at this position Directed evolution of recombinase specificity by split gene reassembly Hybrid lentivirus-phiC31-int-NLS vector allows site-specific recombination in murine and human cells but induces DNA damage.Structure-guided reprogramming of serine recombinase DNA sequence specificity The partitioning and copy number control systems of the selfish yeast plasmid: an optimized molecular design for stable persistence in host cells.Redesigning Recombinase Specificity for Safe Harbor Sites in the Human Genome Chimeric piggyBac transposases for genomic targeting in human cells Redesign of the monomer-monomer interface of Cre recombinase yields an obligate heterotetrameric complex.Vika/vox, a novel efficient and specific Cre/loxP-like site-specific recombination system.Spatially directed assembly of a heterotetrameric Cre-Lox synapse restricts recombination specificity.A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign.Per aspera ad astra: When harmful chromosomal translocations become a plus value in genetic evolution. Lessons from Saccharomyces cerevisiae.Directed evolution of λ integrase activity and specificity by genetic derepression.Efficient Genome Manipulation by Variants of Site-Specific Recombinases R and TD.Selection of bacteriophage lambda integrases with altered recombination specificity by in vitro compartmentalization.A genome-wide analysis of FRT-like sequences in the human genome.Zinc-finger recombinase activities in vitro.Target-specific variants of Flp recombinase mediate genome engineering reactions in mammalian cells.Engineering of a target site-specific recombinase by a combined evolution- and structure-guided approach.Site promiscuity of coliphage HK022 integrase as a tool for gene therapy.Detection of single enzymatic events in rare or single cells using microfluidics.Site-specific chromosomal gene insertion: Flp recombinase versus Cas9 nuclease.Arm site independence of coliphage HK022 integrase in human cells.Engineering altered protein-DNA recognition specificity.

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P2860

Evolution of variants of yeast site-specific recombinase Flp that utilize native genomic sequences as recombination target sites.

http://www.wikidata.org/entity/Q39079092

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

@yue

2006年論文

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2006年論文

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2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

2006年论文

@zh

2006年论文

@zh-cn

name

Evolution of variants of yeast ...... as recombination target sites.

@en

Evolution of variants of yeast ...... as recombination target sites.

@nl

type

label

Evolution of variants of yeast ...... as recombination target sites.

@en

Evolution of variants of yeast ...... as recombination target sites.

@nl

prefLabel

Evolution of variants of yeast ...... as recombination target sites.

@en

Evolution of variants of yeast ...... as recombination target sites.

@nl

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Nucleic Acids Research

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Evolution of variants of yeast ...... as recombination target sites.

@en

P2093

Andrew Paek

http://www.w3.org/2001/XMLSchema#string

Chien-Hui Ma

http://www.w3.org/2001/XMLSchema#string

Jay H Konieczka

http://www.w3.org/2001/XMLSchema#string

Makkuni Jayaram

http://www.w3.org/2001/XMLSchema#string

Swetha Bolusani

http://www.w3.org/2001/XMLSchema#string

Yuri Voziyanov

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P2860

Chimeric recombinases with designed DNA sequence recognition

Crystal structure of a Flp recombinase-Holliday junction complex: assembly of an active oligomer by helix swapping

A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water

Flexibility in DNA recombination: structure of the lambda integrase catalytic core

Molecular organization in site-specific recombination: the catalytic domain of bacteriophage HP1 integrase at 2.7 A resolution

Structure of Cre recombinase complexed with DNA in a site-specific recombination synapse

A model for the mechanism of human topoisomerase I

Conservation of structure and mechanism between eukaryotic topoisomerase I and site-specific recombinases

Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter

Gene targeting using zinc finger nucleases

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5259-5269

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10.1093/NAR/GKL548

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18

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34

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2006-09-26T00:00:00Z

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6791624

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17003057

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1635253

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