Evolution of variants of yeast site-specific recombinase Flp that utilize native genomic sequences as recombination target sites.
about
Targeted DNA mutagenesis for the cure of chronic viral infectionsExpanding the scope of site-specific recombinases for genetic and metabolic engineeringUnveiling hidden catalytic contributions of the conserved His/Trp-III in tyrosine recombinases: assembly of a novel active site in Flp recombinase harboring alanine at this positionDirected evolution of recombinase specificity by split gene reassemblyHybrid lentivirus-phiC31-int-NLS vector allows site-specific recombination in murine and human cells but induces DNA damage.Structure-guided reprogramming of serine recombinase DNA sequence specificityThe partitioning and copy number control systems of the selfish yeast plasmid: an optimized molecular design for stable persistence in host cells.Redesigning Recombinase Specificity for Safe Harbor Sites in the Human GenomeChimeric piggyBac transposases for genomic targeting in human cellsRedesign of the monomer-monomer interface of Cre recombinase yields an obligate heterotetrameric complex.Vika/vox, a novel efficient and specific Cre/loxP-like site-specific recombination system.Spatially directed assembly of a heterotetrameric Cre-Lox synapse restricts recombination specificity.A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cellsEnhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign.Per aspera ad astra: When harmful chromosomal translocations become a plus value in genetic evolution. Lessons from Saccharomyces cerevisiae.Directed evolution of λ integrase activity and specificity by genetic derepression.Efficient Genome Manipulation by Variants of Site-Specific Recombinases R and TD.Selection of bacteriophage lambda integrases with altered recombination specificity by in vitro compartmentalization.A genome-wide analysis of FRT-like sequences in the human genome.Zinc-finger recombinase activities in vitro.Target-specific variants of Flp recombinase mediate genome engineering reactions in mammalian cells.Engineering of a target site-specific recombinase by a combined evolution- and structure-guided approach.Site promiscuity of coliphage HK022 integrase as a tool for gene therapy.Detection of single enzymatic events in rare or single cells using microfluidics.Site-specific chromosomal gene insertion: Flp recombinase versus Cas9 nuclease.Arm site independence of coliphage HK022 integrase in human cells.Engineering altered protein-DNA recognition specificity.
P2860
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P2860
Evolution of variants of yeast site-specific recombinase Flp that utilize native genomic sequences as recombination target sites.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Evolution of variants of yeast ...... as recombination target sites.
@en
Evolution of variants of yeast ...... as recombination target sites.
@nl
type
label
Evolution of variants of yeast ...... as recombination target sites.
@en
Evolution of variants of yeast ...... as recombination target sites.
@nl
prefLabel
Evolution of variants of yeast ...... as recombination target sites.
@en
Evolution of variants of yeast ...... as recombination target sites.
@nl
P2093
P2860
P356
P1476
Evolution of variants of yeast ...... as recombination target sites.
@en
P2093
Andrew Paek
Chien-Hui Ma
Jay H Konieczka
Makkuni Jayaram
Swetha Bolusani
Yuri Voziyanov
P2860
P304
P356
10.1093/NAR/GKL548
P407
P577
2006-09-26T00:00:00Z