Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance - Wikidata - awgldk - TriplyDB

Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

http://www.wikidata.org/entity/Q24682390

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Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelin HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression CD81 promotes both the degradation of transferrin receptor 2 (TfR2) and the Tfr2-mediated maintenance of hepcidin expression Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator Neogenin-mediated hemojuvelin shedding occurs after hemojuvelin traffics to the plasma membrane A Survey of Strategies to Modulate the Bone Morphogenetic Protein Signaling Pathway: Current and Future Perspectives Laboratory use of hepcidin in renal transplant recipients Targeting BMP signalling in cardiovascular disease and anaemia Hepcidin: regulation of the master iron regulator The hepcidin-ferroportin system as a therapeutic target in anemias and iron overload disorders TGF-β signaling in C. elegans Mechanisms of mammalian iron homeostasis The role of TMPRSS6/matriptase-2 in iron regulation and anemia Tumor necrosis factor α inhibits expression of the iron regulating hormone hepcidin in murine models of innate colitis BMP signaling modulates hepcidin expression in zebrafish embryos independent of hemojuvelin Molecular basis of HFE-hemochromatosis.Hepcidin and iron regulation, 10 years later.The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin Molecular biology, genetics and biochemistry of the repulsive guidance molecule family Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin Iron regulation by hepcidin Modifying factors of the HFE hemochromatosis phenotype Maresin 1 ameliorates iron-deficient anemia in IL-10(-/-) mice with spontaneous colitis by the inhibition of hepcidin expression though the IL-6/STAT3 pathway Evidence for a lack of a direct transcriptional suppression of the iron regulatory peptide hepcidin by hypoxia-inducible factors Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis Lack of the bone morphogenetic protein BMP6 induces massive iron overload A low-molecular-weight compound K7174 represses hepcidin: possible therapeutic strategy against anemia of chronic disease Suppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 protein Hepcidin expression in the liver of rats fed a magnesium-deficient diet Pathways for the regulation of hepcidin expression in anemia of chronic disease and iron deficiency anemia in vivo Unlocking biomarker discovery: large scale application of aptamer proteomic technology for early detection of lung cancer Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism Effects of iron loading on muscle: genome-wide mRNA expression profiling in the mouse HFE mutations modulate the effect of iron on serum hepcidin-25 in chronic hemodialysis patients.Targeting the hepcidin-ferroportin axis in the diagnosis and treatment of anemias Hepcidin and sports anemia Hepcidin antagonists for potential treatments of disorders with hepcidin excess.Dragon enhances BMP signaling and increases transepithelial resistance in kidney epithelial cells.

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Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

http://www.wikidata.org/entity/Q24682390

description

2007 nî lūn-bûn

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2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2007 թվականի հուլիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年學術文章

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Modulation of bone morphogenet ...... egulates systemic iron balance

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Modulation of bone morphogenet ...... egulates systemic iron balance

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Modulation of bone morphogenet ...... egulates systemic iron balance

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Modulation of bone morphogenet ...... egulates systemic iron balance

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Modulation of bone morphogenet ...... egulates systemic iron balance

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Modulation of bone morphogenet ...... egulates systemic iron balance

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Modulation of bone morphogenet ...... egulates systemic iron balance

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Modulation of bone morphogenet ...... egulates systemic iron balance

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Modulation of bone morphogenet ...... egulates systemic iron balance

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Modulation of bone morphogenet ...... egulates systemic iron balance

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P2093

Franklin W Huang

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Herbert Y Lin

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Jodie L Babitt

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Nancy C Andrews

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Yin Xia

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Yisrael Sidis

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P2860

LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity

Hepcidin, a urinary antimicrobial peptide synthesized in the liver

DRAGON, a bone morphogenetic protein co-receptor

Interleukin-6 induces hepcidin expression through STAT3

STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

A mouse model of juvenile hemochromatosis.

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