Lack of the bone morphogenetic protein BMP6 induces massive iron overload
about
Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasisIron, hepcidin, and the metal connectionHFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expressionThe transcription factor ATOH8 is regulated by erythropoietic activity and regulates HAMP transcription and cellular pSMAD1,5,8 levelsHypoxic regulation of erythropoiesis and iron metabolismRegulation of cellular iron metabolismThe liver-specific microRNA miR-122 controls systemic iron homeostasis in miceHepcidin: A Promising Therapeutic Target for Iron Disorders: A Systematic ReviewTargeting BMP signalling in cardiovascular disease and anaemiaHepcidin: regulation of the master iron regulatorThe hepcidin-ferroportin system as a therapeutic target in anemias and iron overload disordersRegulation of Iron Metabolism by Hepcidin under Conditions of InflammationOveractive bone morphogenetic protein signaling in heterotopic ossification and Duchenne muscular dystrophyHepcidin and iron homeostasisMurine mutants in the study of systemic iron metabolism and its disorders: an update on recent advancesMechanisms of mammalian iron homeostasisThe role of TMPRSS6/matriptase-2 in iron regulation and anemiaModulation of hepcidin as therapy for primary and secondary iron overload disorders: preclinical models and approachesTumor necrosis factor α inhibits expression of the iron regulating hormone hepcidin in murine models of innate colitisBMP signaling modulates hepcidin expression in zebrafish embryos independent of hemojuvelinEffect of Erythropoietin, Iron Deficiency and Iron Overload on Liver Matriptase-2 (TMPRSS6) Protein Content in Mice and RatsMolecular basis of HFE-hemochromatosis.Hepcidin and iron regulation, 10 years later.Identification of erythroferrone as an erythroid regulator of iron metabolismIron regulation by hepcidinEvidence for a lack of a direct transcriptional suppression of the iron regulatory peptide hepcidin by hypoxia-inducible factorsAge-dependent retinal iron accumulation and degeneration in hepcidin knockout miceRole of hepcidin in the setting of hypoferremia during acute inflammationNeogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasisBmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degenerationSuppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 proteinHepcidin expression in the liver of rats fed a magnesium-deficient dietPathways for the regulation of hepcidin expression in anemia of chronic disease and iron deficiency anemia in vivoExome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload.Applications of small molecule BMP inhibitors in physiology and disease.Targeting the hepcidin-ferroportin axis in the diagnosis and treatment of anemiasHepcidin and sports anemiaHepcidin antagonists for potential treatments of disorders with hepcidin excess.Hepcidin targets ferroportin for degradation in hepatocytes.Anemic copper-deficient rats, but not mice, display low hepcidin expression and high ferroportin levels.
P2860
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P248
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P2860
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
description
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
articolo scientifico
@it
artículu científicu espublizáu en 2009
@ast
im April 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/04/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/04/01)
@nl
наукова стаття, опублікована у квітні 2009
@uk
name
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
@ast
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
@en
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
@nl
type
label
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
@ast
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
@en
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
@nl
prefLabel
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
@ast
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
@en
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
@en
P2093
Delphine Meynard
Hélène Coppin
Marie-Paule Roth
Valérie Darnaud
P2860
P2888
P304
P3181
P356
10.1038/NG.320
P407
P577
2009-04-01T00:00:00Z