Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors
about
Engineering HIV-1-resistant T-cells from short-hairpin RNA-expressing hematopoietic stem/progenitor cells in humanized BLT miceSuppression of p75 neurotrophin receptor surface expression with intrabodies influences Bcl-xL mRNA expression and neurite outgrowth in PC12 cellsOrganic small hairpin RNAs (OshR): a do-it-yourself platform for transgene-based gene silencing.Complete, gene-specific siRNA libraries: production and expression in mammalian cells.Inducible transgenic rat model for diabetes mellitus based on shRNA-mediated gene knockdown.Small interfering RNA targeting m2 gene induces effective and long term inhibition of influenza A virus replication.A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model.Artificial microRNAs as siRNA shuttles: improved safety as compared to shRNAs in vitro and in vivo.The effects of stem length and core placement on shRNA activityOff-target effects of the septin drug forchlorfenuron on nonplant eukaryotesEvaluation of RNA-knockdown strategies for modulation of cytochrome P450 reductase activity in mouse hepatocytesA single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression.Inhibition of HIV-1 infection by a unique short hairpin RNA to chemokine receptor 5 delivered into macrophages through hematopoietic progenitor cell transductionImmune activation and target organ damage are consequences of hydrodynamic treatment but not delivery of naked siRNAs in mice.Stable reduction of CCR5 by RNAi through hematopoietic stem cell transplant in non-human primates.RNA interference as a potential tool in the treatment of leukaemia.A single-chain variable fragment intrabody prevents intracellular polymerization of Z α1-antitrypsin while allowing its antiproteinase activityRNA interference in biology and diseaseFunctional knock down of VCAM1 in mice mediated by endoplasmatic reticulum retained intrabodiesEffect of Regulatory Element DNA Methylation on Tissue-Type Plasminogen Activator Gene Expression.Intraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice.The RNA interference revolution.Therapeutic short hairpin RNA expression in the liver: viral targets and vectors.Enhancing and confirming the specificity of RNAi experiments.Ethical perspectives on RNA interference therapeutics.miRNA-embedded shRNAs for Lineage-specific BCL11A Knockdown and Hemoglobin F InductionBlocking translocation of cell surface molecules from the ER to the cell surface by intracellular antibodies targeted to the ER.Minimizing variables among hairpin-based RNAi vectors reveals the potency of shRNAsOptimization and functional effects of stable short hairpin RNA expression in primary human lymphocytes via lentiviral vectors.Merging molecular imaging and RNA interference: early experience in live animalsInsulin receptor substrate-1/2 mediates IL-4-induced migration of human airway epithelial cellsChronic reduction of the cytosolic or mitochondrial NAD(P)-malic enzyme does not affect insulin secretion in a rat insulinoma cell line.RNA Interference-Induced Innate Immunity, Off-Target Effect, or Immune Adjuvant?Countering hepatitis B virus infection using RNAi: how far are we from the clinic?Prospect of induced pluripotent stem cell genetic repair to cure genetic diseases.Lentiviral vector-mediated RNA silencing in the central nervous system.Effects of transgenic sterilization constructs and their repressor compounds on hatch, developmental rate and early survival of electroporated channel catfish embryos and fry.Lentiviral vectors encoding short hairpin RNAs efficiently transduce and knockdown LINGO-1 but induce an interferon response and cytotoxicity in central nervous system neurones.Effect of ATRA and ATO on the expression of tissue factor in NB4 acute promyelocytic leukemia cells and regulatory function of the inflammatory cytokines TNF and IL-1β.TNFAIP8 overexpression: a potential predictor of lymphatic metastatic recurrence in pN0 esophageal squamous cell carcinoma after Ivor Lewis esophagectomy.
P2860
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P2860
Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Short-term cytotoxic effects a ...... vered using lentiviral vectors
@ast
Short-term cytotoxic effects a ...... vered using lentiviral vectors
@en
Short-term cytotoxic effects a ...... vered using lentiviral vectors
@nl
type
label
Short-term cytotoxic effects a ...... vered using lentiviral vectors
@ast
Short-term cytotoxic effects a ...... vered using lentiviral vectors
@en
Short-term cytotoxic effects a ...... vered using lentiviral vectors
@nl
prefLabel
Short-term cytotoxic effects a ...... vered using lentiviral vectors
@ast
Short-term cytotoxic effects a ...... vered using lentiviral vectors
@en
Short-term cytotoxic effects a ...... vered using lentiviral vectors
@nl
P2860
P356
P1476
Short-term cytotoxic effects a ...... vered using lentiviral vectors
@en
P2093
Egbert K O Kruithof
Richard J Fish
P2860
P2888
P356
10.1186/1471-2199-5-9
P407
P577
2004-08-03T00:00:00Z
P5875
P6179
1001833390