A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model. - Wikidata - awgldk - TriplyDB

A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model.

A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model.

http://www.wikidata.org/entity/Q33697336

about

Engineering HIV-1-resistant T-cells from short-hairpin RNA-expressing hematopoietic stem/progenitor cells in humanized BLT mice In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells Stem-cell-based gene therapy for HIV infection Targeted DNA mutagenesis for the cure of chronic viral infections Controlling HIV-1: Non-Coding RNA Gene Therapy Approaches to a Functional Cure Studies of retroviral infection in humanized mice Pre-clinical modeling of CCR5 knockout in human hematopoietic stem cells by zinc finger nucleases using humanized mice Combinatorial RNA-based gene therapy for the treatment of HIV/AIDS New generation humanized mice for virus research: comparative aspects and future prospects Gene therapy strategies for HIV/AIDS: preclinical modeling in humanized mice Hematopoietic-stem-cell-based gene therapy for HIV disease Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV Controlling the HIV/AIDS epidemic: current status and global challenges Closing the door to human immunodeficiency virus.Dynamics of HSPC repopulation in nonhuman primates revealed by a decade-long clonal-tracking study.Genetic Modulation Therapy Through Stem Cell Transplantation for Human Immunodeficiency Virus 1 Infection.CD25 preselective anti-HIV vectors for improved HIV gene therapy.Development of an efficient recombinant mosquito densovirus-mediated RNA interference system and its preliminary application in mosquito control.Transmembrane protein aptamers that inhibit CCR5 expression and HIV coreceptor function Current humanized mouse models for studying human immunology and HIV-1 immuno-pathogenesis.Chemokine receptor 5 knockout strategies.Stem cell-based anti-HIV gene therapy.Mice with human immune system components as in vivo models for infections with human pathogens.The utility of the new generation of humanized mice to study HIV-1 infection: transmission, prevention, pathogenesis, and treatment.Eradicating HIV-1 infection: seeking to clear a persistent pathogen.Modulation of Gene Expression by Polymer Nanocapsule Delivery of DNA Cassettes Encoding Small RNAs.Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells.Lentivector Knockdown of CCR5 in Hematopoietic Stem and Progenitor Cells Confers Functional and Persistent HIV-1 Resistance in Humanized Mice.Cocaine-mediated impact on HIV infection in humanized BLT mice.Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4(+) T cell resistance and enrichment.BLT humanized mice as a small animal model of HIV infection.Progress on RNAi-based molecular medicines.Novel AgoshRNA molecules for silencing of the CCR5 co-receptor for HIV-1 infection.Ectopic expression of anti-HIV-1 shRNAs protects CD8(+) T cells modified with CD4ζ CAR from HIV-1 infection and alleviates impairment of cell proliferation.Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice.A Simple Mouse Model for the Study of Human Immunodeficiency Virus.Nipah virus envelope-pseudotyped lentiviruses efficiently target ephrinB2-positive stem cell populations in vitro and bypass the liver sink when administered in vivo Using the BLT humanized mouse as a stem cell based gene therapy tumor model.HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem Cells.MicroRNA-34b promoter hypermethylation induces CREB overexpression and contributes to myeloid transformation.

P2860

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P2860

A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model.

http://www.wikidata.org/entity/Q33697336

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

A highly efficient short hairp ...... ans in the hu-BLT mouse model.

@ast

A highly efficient short hairp ...... ans in the hu-BLT mouse model.

@en

type

label

A highly efficient short hairp ...... ans in the hu-BLT mouse model.

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A highly efficient short hairp ...... ans in the hu-BLT mouse model.

@en

prefLabel

A highly efficient short hairp ...... ans in the hu-BLT mouse model.

@ast

A highly efficient short hairp ...... ans in the hu-BLT mouse model.

@en

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A highly efficient short hairp ...... ans in the hu-BLT mouse model.

@en

P2093

Angela Chen

http://www.w3.org/2001/XMLSchema#string

Balamurugan Arumugam

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Dong Sung An

http://www.w3.org/2001/XMLSchema#string

Greg Bristol

http://www.w3.org/2001/XMLSchema#string

Irvin S Y Chen

http://www.w3.org/2001/XMLSchema#string

Jerome A Zack

http://www.w3.org/2001/XMLSchema#string

Joshua Boyer

http://www.w3.org/2001/XMLSchema#string

Lauren Pokomo

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Naoya Koizumi

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Otto Yang

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P2860

Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice

T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice

Functional deletion of the CCR5 receptor by intracellular immunization produces cells that are refractory to CCR5-dependent HIV-1 infection and cell fusion

Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation

Expression profiling reveals off-target gene regulation by RNAi

Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease

Activation of the interferon system by short-interfering RNAs

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1534-1544

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scholarly article

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10.1182/BLOOD-2009-04-215855

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P433

8

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115

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40696280

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20018916

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2830759

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